RESUMO

Bocavirus was found in 11.6% of hospitalized children and 13% of ambulatory patients with exacerbations of asthma, and respiratory syncytial virus was found in 13.5% and 17.7%, respectively. In addition, influenza A virus was detected in 2.6% of hospitalized children and 14.1% (P<.001) of ambulatory-treated patients. Thus, the influenza burden in asthma may be underestimated.

Assuntos

Asma/complicações , Influenza Humana/complicações , Adolescente , Assistência Ambulatorial/estatística & dados numéricos , Criança , Pré-Escolar , Hospitalização/estatística & dados numéricos , Humanos , Lactente , Estudos Prospectivos , Índice de Gravidade de Doença

RESUMO

Real-time polymerase chain reaction for human bocavirus (HBoV) was performed in nasopharyngeal aspirate specimens from 166 children over 2 years of age hospitalized for severe asthma exacerbation. Whereas HBoV was detected in 21 of these children (13%), it was found in only 1 of 50 ambulatory children with stable asthma (2%), suggesting a major role of HBoV in acute exacerbations in asthmatic children.

Assuntos

Asma/virologia , Bocavirus/isolamento & purificação , Nasofaringe/virologia , Infecções por Parvoviridae/epidemiologia , Adolescente , Bocavirus/genética , Criança , Pré-Escolar , DNA Viral/isolamento & purificação , Feminino , Hospitalização , Humanos , Masculino , Reação em Cadeia da Polimerase , Estudos Prospectivos , Estações do Ano , Índice de Gravidade de Doença