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1.
Surg Neurol Int ; 13: 187, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35673653

RESUMO

Background: Several approaches are described for giant meningiomas of the anterior skull base. Recently, endonasal endoscopic approaches have been described as a minimally invasive (MI) alternative. However, the extension of dissection of the nose cavity and the risks of CSF leak do not fit in the MI prerogatives. We present an operative video illustrating a MI transcortical approach through a nummular craniotomy for a giant meningioma of the anterior fossa. Case Description: We report an 83-year-old female patient. On neurological examination, she was drowsy and hemiparetic on the left side. MRI scan demonstrated a giant anterior fossa lesion (7.6 × 6.2 × 6 cm). An 1.5 diameter craniotomy was placed in the right frontal region after MRI 3D reconstruction analysis. The first step was to debulk the core of the tumor with the ultrasonic aspirator. An important aspect is that the surgeon needs to rotate its positions around the patient in a 360° fashion for a total resection. The final step was to inspect the surgical cavity with the endoscope to check for any remaining tumor. The patient was discharged home 1 day after the surgery with no new deficits. Conclusion: Giant meningiomas of the anterior fossa are a different entity. When they reach the cortical surface, the surgical approach can be different from the common skull base meningiomas. We demonstrate that a MI transcortical approach can be a safe alternative for giant meningiomas, especially for high-risk patients, as the elderly ones.

2.
World Neurosurg ; 157: 3-12, 2022 01.
Artigo em Inglês | MEDLINE | ID: mdl-34582999

RESUMO

BACKGROUND: Surgical planning for treating brain arteriovenous malformations (bAVMs) is challenging because it entails visualizing 3-dimensional (3D) relationships between the nidus, its feeding and en passage arteries, and draining veins. Surgical experience in developing the capacity to mentally visualize pathological bAVM angioarchitecture could be complemented by this software, and thus potentially lower the steep learning curve for understanding complex bAVM angioarchitecture. We evaluated the clinical application of freely available online 3D reconstruction software in facilitating visualization of AVM angioarchitecture for presurgical planning. METHODS: Preoperative Digital Imaging and Communications in Medicine magnetic resonance imaging/magnetic resonance angiography images of 56 superficial bAVMs from 2013 to 2018 were processed using open-source software Horos. 3D rendered images were compared with the surgical view to evaluate software accuracy and determine its value as a preoperative tool. 3D reconstructed images were compared with intraoperative recordings. RESULTS: A useful image identifying both the main feeding artery and draining vein was achieved in 35 of 56 cases (62.5%). Reconstructions of small AVMs (nidus ≤2 cm) and those located within the temporal or cerebellar cortex were less useful due to soft tissue artifacts. Frontal and parietal lobe lesions had significantly higher rates of identifying feeding arteries and draining veins (P < 0.05). CONCLUSION: Presurgical planning for resection of superficial bAVMs using Horos software allows for a comprehensive 3D analysis of the bAVM angioarchitecture. This technique is most useful for frontal and parietal lobe lesions, and aids the surgeon in formulating an optimal surgical strategy. The 3D reconstruction of the brain surface offers a surgical map not influenced by brain shift.


Assuntos
Malformações Arteriovenosas Intracranianas/diagnóstico por imagem , Malformações Arteriovenosas Intracranianas/cirurgia , Procedimentos Neurocirúrgicos/métodos , Planejamento de Assistência ao Paciente , Software , Adolescente , Adulto , Idoso , Angiografia Digital , Angiografia Cerebral , Artérias Cerebrais/diagnóstico por imagem , Artérias Cerebrais/cirurgia , Veias Cerebrais/diagnóstico por imagem , Veias Cerebrais/cirurgia , Criança , Pré-Escolar , Feminino , Humanos , Processamento de Imagem Assistida por Computador , Imageamento Tridimensional , Angiografia por Ressonância Magnética , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Reprodutibilidade dos Testes , Adulto Jovem
3.
Oper Neurosurg (Hagerstown) ; 13(1): 2-14, 2017 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-28931250

RESUMO

BACKGROUND: Although anterior temporal lobectomy may be a definitive surgical treatment for epileptic patients with mesial temporal sclerosis, it often results in verbal, visual, and cognitive dysfunction. Studies have consistently reported the advantages of selective procedures compared with a standard anterior temporal lobectomy, mainly in terms of neuropsychological outcomes. OBJECTIVE: To describe a new technique to perform a selective amygdalohippocampectomy (SAH) through a transpalpebral approach with endoscopic assistance. METHODS: A mini fronto-orbitozygomatic craniotomy through an eyelid incision was performed in 8 patients. Both a microscope and neuroendoscope were used in the surgeries. An anterior SAH was performed in 5 patients who had the diagnosis of temporal lobe epilepsy with mesial temporal sclerosis. One patient had a mesial temporal lesion suggesting a ganglioglioma. Two patients presented mesial temporal cavernomas with seizures originating from the temporal lobe. RESULTS: The anterior approach allowed removal of the amygdala and hippocampus. The image-guided system and postoperative evaluation confirmed that the amygdala may be accessed and completely removed through this route. The hippocampus was partially resected. All patients have discontinued medication with no more epileptic seizures. The patients with cavernomas and ganglioglioma also had their lesions completely removed. One-year follow-up has shown no visible scars. CONCLUSION: The anterior route for SAH is a rational and direct approach to the mesial temporal lobe. Anterior SAH is a safe, less invasive procedure that provides early identification of critical vascular and neural structures in the basal cisterns. The transpalpebral approach provides a satisfactory cosmetic outcome.


Assuntos
Tonsila do Cerebelo/cirurgia , Túnica Conjuntiva/cirurgia , Endoscopia/métodos , Hipocampo/cirurgia , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Adulto , Idoso , Tonsila do Cerebelo/diagnóstico por imagem , Neoplasias Encefálicas/complicações , Neoplasias Encefálicas/diagnóstico por imagem , Neoplasias Encefálicas/cirurgia , Transtornos Cognitivos/etiologia , Transtornos Cognitivos/cirurgia , Túnica Conjuntiva/diagnóstico por imagem , Craniotomia/métodos , Eletroencefalografia , Epilepsia do Lobo Temporal/complicações , Epilepsia do Lobo Temporal/diagnóstico por imagem , Epilepsia do Lobo Temporal/cirurgia , Feminino , Lobo Frontal/cirurgia , Hemangioma Cavernoso/complicações , Hemangioma Cavernoso/diagnóstico por imagem , Hemangioma Cavernoso/cirurgia , Hipocampo/diagnóstico por imagem , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Resultado do Tratamento
4.
Oper Neurosurg (Hagerstown) ; 13(4): 453-464, 2017 08 01.
Artigo em Inglês | MEDLINE | ID: mdl-28838124

RESUMO

BACKGROUND: Although recent technological advances have led to successful endovascular treatment, middle cerebral artery (MCA) aneurysms are still prone to surgery. Because minimally invasive options are limited and possess several functional and cosmetic drawbacks, a transpalpebral approach is proposed as a new alternative. OBJECTIVES: To describe and assess surgical results of the minimally invasive transpalpebral approach in patients with MCA aneurysms. METHODS: The data of 25 patients with unruptured MCA aneurysms from 2013 to 2016 were included in a cohort prospective database. We describe modifications of the approach and technique for MCA aneurysm clipping, in a step-by-step manner. The outcome was based on complications, procedural morbidity and mortality, and clinical and angiographic outcomes. RESULTS: All procedures were successfully performed in a standardized way, and no major complications related to the new approach were observed. Twenty-two patients were discharged the day after surgery (88%). The majority of aneurysms were 5 to 6 mm in diameter (mean, 7 mm; range 4-21 mm). All patients underwent postoperative angiographic control, which showed no significant residual neck. A 3-mo follow-up was sufficient to show no visible scars with excellent cosmetic results. The mean duration of follow-up was 16 mo. CONCLUSION: The transpalpebral approach comes as a minimally invasive, safe, definitive, and cosmetically adequate solution for MCA aneurysms at the present time.


Assuntos
Craniotomia/métodos , Aneurisma Intracraniano/cirurgia , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Órbita/cirurgia , Adulto , Idoso , Angiografia Digital , Angiografia por Tomografia Computadorizada , Pálpebras/cirurgia , Feminino , Humanos , Aneurisma Intracraniano/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Neuronavegação , Estudos Prospectivos , Estudos Retrospectivos , Resultado do Tratamento
5.
J Surg Case Rep ; 2015(11)2015 Nov 03.
Artigo em Inglês | MEDLINE | ID: mdl-26537390

RESUMO

The endoscopic technique has been described as a minimally invasive method for spontaneous hematoma evacuation, as a safe and effective treatment. Nevertheless, to our knowledge, there is no description of a technical report of traumatic intracerebral hematoma removal using the neuroendoscope. A 47-year-old man was admitted sustaining 13 points in Glasgow coma scale with brain computed tomography (CT) scan showing a temporal contusion. Guided by a 3D reconstructed CT, using the program OsiriX®, the posterior limit of the hematoma was identified. A burr hole was placed at the posterior temporal region, and we used the neuroendoscope to assist the hematoma evacuation. The postoperative tomography showed adequate hematoma removal. He was discharged from hospital 48 h after surgery. Two weeks later, he was conscious and oriented temporally. This endoscopic-assisted technique can provide safe removal of traumatic hematomas of the temporal lobe.

6.
Sensors (Basel) ; 13(5): 6477-91, 2013 May 16.
Artigo em Inglês | MEDLINE | ID: mdl-23681091

RESUMO

The evaluation of patients in the emergency room department (ER) through more accurate imaging methods such as computed tomography (CT) has revolutionized their assistance in the early 80s. However, despite technical improvements seen during the last decade, surgical planning in the ER has not followed the development of image acquisition methods. The authors present their experience with DICOM image processing as a navigation method in the ER. The authors present 18 patients treated in the Emergency Department of the Hospital das Clínicas of the University of Sao Paulo. All patients were submitted to volumetric CT. We present patients with epidural hematomas, acute/subacute subdural hematomas and contusional hematomas. Using a specific program to analyze images in DICOM format (OsiriX(®)), the authors performed the appropriate surgical planning. The use of 3D surgical planning made it possible to perform procedures more accurately and less invasively, enabling better postoperative outcomes. All sorts of neurosurgical emergency pathologies can be treated appropriately with no waste of time. The three-dimensional processing of images in the preoperative evaluation is easy and possible even within the emergency care. It should be used as a tool to reduce the surgical trauma and it may dispense methods of navigation in many cases.


Assuntos
Serviço Hospitalar de Emergência , Imageamento Tridimensional/métodos , Neuronavegação/métodos , Procedimentos Neurocirúrgicos/métodos , Software , Adulto , Hematoma/patologia , Hematoma/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Tomografia Computadorizada por Raios X
7.
Mov Disord ; 27(12): 1559-63, 2012 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-23038611

RESUMO

BACKGROUND: Thalamotomies and pallidotomies were commonly performed before the deep brain stimulation (DBS) era. Although ablative procedures can lead to significant dystonia improvement, longer periods of analysis reveal disease progression and functional deterioration. Today, the same patients seek additional treatment possibilities. METHODS: Four patients with generalized dystonia who previously had undergone bilateral pallidotomy came to our service seeking additional treatment because of dystonic symptom progression. Bilateral subthalamic nucleus DBS (B-STN-DBS) was the treatment of choice. The patients were evaluated with the Burke-Fahn-Marsden Dystonia Rating Scale (BFMDRS) and the Unified Dystonia Rating Scale (UDRS) before and 2 years after surgery. RESULTS: All patients showed significant functional improvement, averaging 65.3% in BFMDRS (P = .014) and 69.2% in UDRS (P = .025). CONCLUSIONS: These results suggest that B-STN-DBS may be an interesting treatment option for generalized dystonia, even for patients who have already undergone bilateral pallidotomy.


Assuntos
Estimulação Encefálica Profunda/métodos , Distúrbios Distônicos/terapia , Palidotomia/métodos , Núcleo Subtalâmico/fisiologia , Adulto , Feminino , Lateralidade Funcional , Humanos , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento , Adulto Jovem
8.
Funct Neurol ; 27(4): 207-16, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-23597434

RESUMO

Neurogenic neuroprotection is a promising approach for treating patients with ischemic brain lesions. In rats, stimulation of the deep brain nuclei has been shown to reduce the volume of focal infarction. In this context, protection of neural tissue can be a rapid intervention that has a relatively long-lasting effect, making fastigial nucleus stimulation (FNS) a potentially valuable method for clinical application. Although the mechanisms of neuroprotection induced by FNS remain partially unclear, important data have been presented in the last two decades. A 1-h electrical FNS reduced, by 59%, infarctions triggered by permanent occlusion of the middle cerebral artery in Fisher rats. The acute effect of electrical FNS is likely mediated by a prolonged opening of potassium channels, and the sustained effect appears to be linked to inhibition of the apoptotic cascade. A better understanding of the neuronal circuitry underlying neurogenic neuroprotection may contribute to improving neurological outcomes in ischemic brain insults.


Assuntos
Infarto Encefálico/prevenção & controle , Núcleos Cerebelares/fisiologia , Estimulação Encefálica Profunda/métodos , Animais , Infarto Encefálico/etiologia , Núcleos Cerebelares/anatomia & histologia , Núcleos Cerebelares/metabolismo , Circulação Cerebrovascular/fisiologia , Modelos Animais de Doenças , Encefalite/etiologia , Encefalite/prevenção & controle , Humanos , Infarto da Artéria Cerebral Média/complicações , Vias Neurais/fisiologia , Lobo Parietal/fisiologia
9.
J. bras. neurocir ; 21(3): 182-186, 2010.
Artigo em Português | LILACS | ID: lil-579602

RESUMO

Aspergilose do sistema nervoso central (SNC) é uma doença rara. O uso de corticosteróides tem elevado o número de casos na atualidade. Trata-se de uma doença com uma elevada taxa de letalidade e deve ser tratada de forma agressiva.Métodos: A literatura foi revisada, sendo identificados 38 casos envolvendo aneurismas cerebrais causadas por Aspergillus.Conclusão: A infecção por Aspergillus é muito rara no mundo, mas sua frequência vem se elevando porque a falha de imunocompetência está crescendo. Não há uma apresentação específica desta doença, tornando o diagnóstico muito difícil.O prognóstico é ruim, portanto a doença deve ser tratada precocemente.


Assuntos
Humanos , Masculino , Feminino , Aneurisma Infectado , Aspergillus fumigatus , Aneurisma Intracraniano
10.
Arq Neuropsiquiatr ; 67(1): 74-7, 2009 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-19330216

RESUMO

OBJECTIVE: In the majority of cases, the correct treatment of brain lesions is possible only when the histopathological diagnosis is made. Several deep-seated lesions near eloquent areas are not safely approached by the classical neurosurgical procedures. These patients can get benefit by a minimally invasive procedure. METHOD: We present a series of 176 consecutive patients submitted to stereotactic biopsies due to a great variety of brain lesions. RESULTS: Histological diagnosis found in this series: glioma in 40.1% of the patients, other neoplasms in 12.2% and infectious or inflammatory diseases in 29.1 %. The result was inconclusive in 5.2% of the procedures. One patient died (0.6%) and two (1.2%) presented operative complications. The criteria, advantages and risks of the stereotactic biopsies are discussed. CONCLUSION: The efficacy of the method is adequate and morbid-mortality rates were low.


Assuntos
Biópsia/métodos , Neoplasias Encefálicas/patologia , Encéfalo/patologia , Glioma/patologia , Técnicas Estereotáxicas , Adolescente , Adulto , Idoso de 80 Anos ou mais , Biópsia/efeitos adversos , Biópsia/mortalidade , Neoplasias Encefálicas/cirurgia , Criança , Glioma/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Técnicas Estereotáxicas/efeitos adversos , Técnicas Estereotáxicas/mortalidade , Adulto Jovem
11.
Arq. neuropsiquiatr ; Arq. neuropsiquiatr;67(1): 74-77, Mar. 2009. tab
Artigo em Inglês | LILACS | ID: lil-509111

RESUMO

OBJECTIVE: In the majority of cases, the correct treatment of brain lesions is possible only when the histopathological diagnosis is made. Several deep-seated lesions near eloquent areas are not safely approached by the classical neurosurgical procedures. These patients can get benefit by a minimally invasive procedure. METHOD: We present a series of 176 consecutive patients submitted to stereotactic biopsies due to a great variety of brain lesions. RESULTS: Histological diagnosis found in this series: glioma in 40.1 percent of the patients, other neoplasms in 12.2 percent and infectious or inflammatory diseases in 29.1 percent. The result was inconclusive in 5.2 percent of the procedures. One patient died (0.6 percent) and two (1.2 percent) presented operative complications. The criteria, advantages and risks of the stereotactic biopsies are discussed. CONCLUSION: The efficacy of the method is adequate and morbid-mortality rates were low.


OBJETIVO: O diagnóstico anatomopatológico das lesões encefálicas é muitas vezes necessário para a instituição do tratamento adequado. Entretanto, muitas lesões localizadas profundamente no encéfalo ou em centros nervosos de grande importância funcional não podem ser acessadas sem riscos, com a aplicação dos procedimentos neurocirúrgicos habituais. MÉTODO: Apresentamos uma série de 176 doentes submetidos a biópsias estereotáxicas de lesões encefálicas. RESULTADOS: Em 40,1 por cento dos casos, o diagnóstico foi de glioma, em 12,2 por cento de outras neoplasias e em 29,1 por cento, de doenças infecciosas ou inflamatórias. O resultado foi inconclusivo em 5,2 por cento dos doentes. Um (0,6 por cento) doente faleceu e dois (1,2 por cento) apresentaram graves complicações operatórias. Os critérios de seleção, as vantagens e os riscos da biópsia estereotáxica são discutidos. CONCLUSÃO: A eficácia do método é boa e a morbimortalidade das biópsias estereotáxicas é baixa.


Assuntos
Adolescente , Adulto , Idoso de 80 Anos ou mais , Criança , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Biópsia/métodos , Neoplasias Encefálicas/patologia , Encéfalo/patologia , Glioma/patologia , Técnicas Estereotáxicas , Biópsia/efeitos adversos , Biópsia/mortalidade , Neoplasias Encefálicas/cirurgia , Glioma/cirurgia , Técnicas Estereotáxicas/efeitos adversos , Técnicas Estereotáxicas/mortalidade , Adulto Jovem
12.
Surg Neurol ; 65 Suppl 1: S1:10-1:13, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-16427436

RESUMO

BACKGROUND: The purpose of this article was to assess if high-risk, mildly head-injured patients with normal CT scan present an outcome similar to the group with "low-risk MHI." METHODS: A total of 379 hospital charts of inpatients with Glasgow Coma Scale scores of 13, 14, and 15 were reviewed. Information regarding age, fGCS, trauma mechanism, cranial CT scan findings, hospital course, and follow-up using the GOS were obtained from all patients. RESULTS: Patients were separated in 3 groups: fGCS 13 (46 patients), fGCS 14 (138 patients), and fGCS 15 (195 patients). The groups with different scores on fGCS did not differ regarding CT scan abnormalities, surgical treatment, or outcome. Patients were also separated in 2 groups based on CT scan findings: 266 patients had CT interpreted as abnormal and 113 had CT interpreted as normal. The 2 groups differed statistically regarding surgical treatment and scores on GOS (P < .05). There was no statistically significant difference between the 2 groups regarding sex, trauma mechanism, fGCS, or age. CONCLUSIONS: Our findings support the idea that a normal cranial CT scan in patients with fGCS scores of 13 or higher ascertain a low-risk MHI outcome and, therefore, such patients must be included in this category of traumatic brain injury. On the other hand, patients with cranial CT scan abnormalities should be included in the group with moderate head injury.


Assuntos
Traumatismos Craniocerebrais/diagnóstico por imagem , Escala de Coma de Glasgow , Tomografia Computadorizada por Raios X , Adulto , Traumatismos Craniocerebrais/cirurgia , Feminino , Seguimentos , Humanos , Masculino , Valor Preditivo dos Testes , Estudos Retrospectivos , Fatores de Risco , Resultado do Tratamento
13.
J. bras. neurocir ; 16(1): 35-37, 2005.
Artigo em Português | LILACS | ID: lil-456152

RESUMO

A craniectomia fronto-temporoparietal com duraplastia éuma das opções terapêuticas nos acidentes vasculares cerebraisdo tipo isquêmico (AVCi) com evolução maligna, ou seja, comhipertensão intracraniana refratária, de modo a preservar avida do paciente. O objetivo desta nota técnica é a descriçãode uma técnica de duraplastia destinada a evitar a extrusão dematerial encefálico pelas bordas da abertura dural e o conseqüenteprejuízo do retorno venoso. Material e método: Foirealizada craniectomia fronto-temporoparietal em dez cadáveresadultos frescos, conforme técnica convencional. Um retalho depericrânio, com 12 cm de diâmetro, foi retirado e posicionadosobre a dura-máter, no local a se realizar a abertura dural. Apósa realização de pontos cardeais, cada lado da abertura duralfoi realizado, enquanto simultaneamente suturado o retalhode pericrânio, de modo a evitar a teórica extrusão de tecido encefálico, com bom resultado fi nal. Discussão: A opção pelotratamento cirúrgico, nos casos de AVCi com evolução maligna,permanece um ponto controverso. Nuances técnicas na realizaçãoda craniectomia e duraplastia podem, teoricamente, infl uirno edema perilesional que agrava esta doença com evoluçãotão grave. Um ponto fundamental é o diâmetro mínimo de 12cm para a duraplastia; buscou-se com a descrição desta técnicamelhorar, ainda mais, as condições para que estes pacientestenham melhor evolução. Este estudo cadavérico demonstrauma técnica de fácil execução e bom resultado fi nal; aguardam-se resultados de sua aplicação clínica para verififi car suaverdadeira eficácia.


Assuntos
Humanos , Masculino , Feminino , Adulto , Craniotomia , Infarto , Hipertensão Intracraniana , Artéria Cerebral Média
14.
Neurosurg Focus ; 16(2): ECP1, 2004 Feb 15.
Artigo em Inglês | MEDLINE | ID: mdl-15209492

RESUMO

OBJECT: The authors present their experience in the management of posterior fossa epidural hematoma (PFEDH), which involved an aggressive diagnostic approach with the extensive use of head computerized tomography (CT) scanning. METHODS: The authors treated 43 cases of PFEDH in one of the largest health centers in Brazil. Diagnosis was established in all patients with the aid of CT scanning because the clinical manifestations were frequently nonspecific. Cases were stratified by clinical course, Glasgow Coma Scale score, and their radiological status. Based on clinical and radiological parameters the patients underwent surgical or conservative management. CONCLUSIONS: Compared with outcomes reported in the available literature, good outcome was found in this series. This is primarily due to the broad use of CT scanning for diagnostic and observational purposes, which, in the authors' opinion, led to early diagnosis and prompt treatment.


Assuntos
Fossa Craniana Posterior/lesões , Hematoma Epidural Craniano/cirurgia , Acidentes por Quedas , Acidentes de Trânsito , Adolescente , Adulto , Lesões Encefálicas/complicações , Brasil/epidemiologia , Criança , Pré-Escolar , Feminino , Escala de Coma de Glasgow , Hematoma Epidural Craniano/diagnóstico , Hematoma Epidural Craniano/diagnóstico por imagem , Humanos , Hidrocefalia/etiologia , Hidrocefalia/cirurgia , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Tomografia Computadorizada por Raios X , Resultado do Tratamento
15.
J Neurosurg Anesthesiol ; 15(2): 144-50, 2003 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-12658001

RESUMO

Neurogenic pulmonary edema (NPE) is an underdiagnosed clinical entity. Its pathophysiology is multifactorial but largely unknown. We report two cases of NPE and review the literature on NPE cases reported since 1990. A 21-year-old man had a seizure episode following cranioplasty. He became increasingly dyspneic, and clinical and laboratory signs of respiratory failure were evident. Chest radiography and computed tomography showed bilateral diffuse infiltrates. After supportive measures were taken, complete respiratory recovery occurred in 72 hours. A 52-year-old woman had several seizure episodes following subarachnoid hemorrhage due to a cavernoma. She became increasingly dyspneic upon arrival at the hospital. After tracheostomy and oxygen support were established, chest radiography showed bilateral diffuse infiltrates. Respiratory recovery was excellent, and the patient was eupneic with normal results of chest radiography 48 hours later. Fourteen reports (21 cases) were found. Thirteen patients were female, and the mean age of the patients was 31.6 years. The most frequent underlying factor was subarachnoid hemorrhage (42.9%). Symptom onset occurred <4 hours after the neurologic event in 71.4% of cases. One third of the patients presented with pink frothy sputum. Chest radiography showed bilateral diffuse infiltrates in 90.5% of cases. Supportive measures included oxygen support and vasoactive drugs. Recovery was usually very rapid: 52.4% of patients recovered in <72 hours. Almost 10% of patients died of NPE. Our two cases had clinical and laboratory features in common with most NPE cases. Physicians should remember NPE when neurologic patients suddenly become dyspneic. The mortality rate is high, but surviving patients usually recover very quickly.


Assuntos
Edema Pulmonar/etiologia , Doença Aguda , Adulto , Sistema Nervoso Autônomo/fisiopatologia , Traumatismos Craniocerebrais/complicações , Cuidados Críticos , Epilepsia Tônico-Clônica/complicações , Feminino , Cefaleia/diagnóstico por imagem , Cefaleia/etiologia , Humanos , Masculino , Pessoa de Meia-Idade , Edema Pulmonar/diagnóstico por imagem , Edema Pulmonar/terapia , Tomografia Computadorizada por Raios X , Resultado do Tratamento
16.
J. bras. neurocir ; 14(1): 13-18, 2003.
Artigo em Português | LILACS | ID: lil-456050

RESUMO

Os autores avaliam as dificuldades clínicas pré-operatórias,as complicações e as condutas para o manuseio deriscos nas cirurgias de meningiomas em pacientes idosos.Foram estudados 34 pacientes de 1994 a 2002 com 65 a 86anos de idade. Todos os casos apresentavam algum tipo decomorbidade, estando entre as mais freqüentes: insuficiênciacoronariana, insuficiência cardíaca congestiva, enfisema pulmonar,osteoartrose cervical, diabetes melito e artrite reumatóidedo idoso. A localização mais comum foi parassagitalposterior e convexidade frontal (6 casos cada). Quanto àmorbidade cirúrgica, 2 casos apresentaram déficit motorpermanente e 3 casos foram reabordados para descompressãodevido a infarto venoso extenso por trombose de seio. Trêspacientes morreram no período pós-operatório por associaçãoentre edema cerebral por infarto venoso e complicaçõesde ordem pulmonar. Conclui-se que a cirurgia dosmeningiomas em idosos deve ser meticulosamente programadadevido às co-morbidades inerentes, mas não deve sernegligenciada simplesmente em virtude da idade do paciente.


Assuntos
Humanos , Masculino , Feminino , Idoso , Edema Encefálico , Neoplasias Encefálicas , Meningioma
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