RESUMO
OBJECTIVE: The aim of the present study was to compare the molecular and morphological effects of diacerein and glucosamine-chondroitin drug treatment and intra-articular injection therapy of human deciduous dental pulp stem cells (hDPSCs) in a rat knee model of induced osteoarthritis (OA). MATERIALS AND METHODS: Thirty-six adult male rats were randomly separated into six groups: Control group (without induction of OA), osteoarthritis group 60 (induction of OA, saline gavage started on day 14 and performed for 60 days, followed by euthanasia), osteoarthritis group (induction of OA and euthanasia after 14 days), diacerein group, glucosamine-chondroitin group, and mesenchymal stem cell group. The drug-treated groups were gavaged with 50 mg/kg of diacerein and 400/500 mg/kg of glucosamine-chondroitin starting on dat 14 for 60 days. The cell therapy-treated group received an intra-articular single dose of 8 × 105 hDPSCs on day 14, and euthanasia was performed after 60 days. Lateral femoral condyles were collected and prepared for immunohistochemistry and light microscopy procedures. RESULTS: The morphological features and immunoexpression of SOX-5, IHH, MMP-8, MMP-13, and Type II collagen were statistically analysed. Our data suggest that hDPSC therapy contributes more actively and effectively in the structural reorganization of lateral femoral condyles. In contrast, the glucosamine-chondroitin sulphate treatment was more effective in inflammatory control, while diacerein showed better results associated with the maintenance of the primordial cartilage. CONCLUSIONS: The positive therapeutic effect of daily administered conventional drugs can be confirmed in a rat model of OA. However, one single dose of locally administered hDPSCs provides significant improvement in tissue regeneration in an OA model.
Assuntos
Antraquinonas/uso terapêutico , Condroitina/uso terapêutico , Modelos Animais de Doenças , Glucosamina/uso terapêutico , Células-Tronco Mesenquimais/citologia , Osteoartrite/terapia , Animais , Polpa Dentária/citologia , Relação Dose-Resposta a Droga , Humanos , Injeções Intra-Articulares , Masculino , Osteoartrite/patologia , Ratos , Ratos WistarRESUMO
OBJECTIVE: The aim of the present study was to compare the molecular and morphological effects of diacerein and glucosamine-chondroitin drug treatment and intra-articular injection herapy of human deciduous dental pulp stem cells (hDPSCs) in a rat knee model of induced osteoarthritis OA. MATERIALS AND METHODS: Thirty-six adult male rats were randomly separated into six groups: Control group without induction of OA, osteoarthritis group 60 induction of OA, saline gavage started on day 14 and performed for 60 days, followed by euthanasia, osteoarthritis group induction of OA and euthanasia after 14 days, diacerein group, glucosamine-chondroitin group, and mesenchymal stem cell group. The drug-treated groups were gavaged with 50 mg/kg of diacerein and 400/500 mg/kg of glucosamine-chondroitin starting on dat 14 for 60 days. The cell therapy-treated group received an intra-articular single dose of 8 × 105 hDPSCs on day 14, and euthanasia was performed after 60 days. Lateral femoral condyles were collected and prepared for immunohistochemistry and light microscopy procedures. RESULTS: The morphological features and immunoexpression of SOX-5, IHH, MMP-8, MMP-13, and Type II collagen were statistically analysed. Our data suggest that hDPSC therapy contributes more actively and effectively in the structural reorganization of lateral femoral condyles. In contrast, the glucosamine-chondroitin sulphate treatment was more effective in inflammatory control, while diacerein showed better results associated with the maintenance of the primordial cartilage. CONCLUSIONS: The positive therapeutic effect of daily administered conventional drugs can be confirmed in a rat model of OA. However, one single dose of locally administered hDPSCs provides significant improvement in tissue regeneration in an OA model.
RESUMO
Copitarsia sp. (Hampson) (Lepidoptera: Noctuidae: Cuculliinae) is a quarantine pest in different countries and affects diverse crops of economic importance in South America. The development of ethological control strategies is an important issue that requires knowing the reproductive behavior of the species involved. Therefore, the aim of this study was to establish the reproductive behavior of Copitarsia uncilata (Burgos & Leiva) and to evaluate the attractiveness of synthetic pheromone compounds under laboratory conditions. Observations of nocturnal reproductive behavior of males and females were performed for 7 days in order to register the courtship, mating, and oviposition time. Once the period of the highest reproductive activity was identified, flight behavior and attraction of virgin males were evaluated in a wind tunnel towards synthetic compounds previously reported as commercial pheromones for Copitarsia species, namely (Z)-tetradec-9-enyl acetate (Z9-14Ac), (Z)-tetradec-9-enol (Z9-14OH), and their mixture (Z9-14Ac + Z9-14OH at 4:1 ratio), in comparison with virgin females and clean air flow. We observed that reproductive behavior occurs during the first third of the scotophase and begins on the second day after adult emergence. Highest proportion of courtship and mating occurs on days 2 and 3 after emergence, and oviposition starts the night immediately after the first mating. Wind tunnel assessments showed that males were highly attracted to calling females compared with the blend of synthetic pheromone compounds, with 89% and 12% of males landing at the source, respectively. Moreover, males also showed a low response to the isolated compounds (Z9-14Ac 14% and Z9-14OH 4%).
Assuntos
Mariposas/fisiologia , Atrativos Sexuais/química , Comportamento Sexual Animal , Animais , Feminino , Voo Animal , Masculino , OviposiçãoRESUMO
In Colombia, Copitarsia uncilata Burgos & Leiva has been reported as a pest of ornamental flowers. The leafworm causes serious economic losses to farmers because the shipments are intercepted at the detection sites. The identification and subsequent synthesis of the sex pheromone compounds can lead to the use of semiochemicals as an important strategy to complement the pest management. This paper identifies and characterizes the chemical components of the female sexual gland of C. uncilata at three different age stages in order to relate the effect of age on the gland extract composition. Eggs and larvae were collected from commercial crops. The specimens were reared and sexed. Pheromone glands of intact females were excised at (a) 1-2, (b) 3-4, and (c) 5-6 days old. The extracts were analyzed using GC-MS after two extraction time points: 20 min and 8 days. The extracts from the third age stage showed an increase in concentration for 35% of the compounds after 8 days of storage. The relative abundance as a function of the female age showed two trends: an upward trend, where the relative abundances of the compounds increased through the age stages, while some compounds shown a downward trend. Within the first trend, mostly of the compounds were found to be related with infochemicals type structures, where tetradec-9-en-1-yl acetate (within several C-14 long-chain alcohols) is the main one. The 9-14:Ac quadrupled concentration through the ages is possibly related to the increased length of calling period as female moth age.
Assuntos
Lepidópteros/química , Feromônios/química , Atrativos Sexuais/química , Animais , Feminino , Cromatografia Gasosa-Espectrometria de Massas , Larva , MariposasRESUMO
Introducción: Un porcentaje significativo de personas que adquieren una lesión cerebral necesita programas de rehabilitación ambulatoria. En Chile predomina aún un modelo biomédico de rehabilitación, no obstante, las nuevas guías clínicas recomiendan un abordaje interdisciplinario que considere las necesidades del paciente y su familia. Actualmente existe un vacío respecto a cómo operacionalizar intervenciones eficaces que respondan a este paradigma. Objetivo: Encontrar evidencia que permita el desarrollo y evaluación de enfoques en neurorehabilitación ambulatoria de personas con lesión cerebral adquirida y las posibles metodologías de operacionalización de estos. Metodología: Revisión inductiva y conceptual de la literatura. Resultados: En la literatura chilena no existe evidencia empírica ni desarrollos sistemáticos sobre los fundamentos y la efectividad de los programas de rehabilitación ambulatoria para estas personas. En la literatura internacional se destacan tres enfoques: el enfoque holista, el centrado en el cliente y el basado en la planificación de metas. Si bien tales enfoques permiten guiar las acciones de los equipos, la evidencia de su efectividad, en base al criterio de expertos y pequeños estudios longitudinales y de caso único, es aun limitada. Conclusiones: Esencial a la construcción de identidad de un equipo de rehabilitación es determinar los principios y enfoques que sustente su labor. La complejidad y diversidad de los pacientes en la fase ambulatoria requiere que los equipos posean claros fundamentos para guiar la constante toma de decisiones. Es necesaria la evaluación de la eficacia de los programas de rehabilitación ambulatoria en Chile, desarrollando metodologías acordes a la naturaleza multifactorial del fenómeno.
Introduction: A significant percentage of people who acquire a Brain Injury need outpatient rehabilitation programs. In Chile the rehabilitation field is in a transitional stage. Even though the biomedical model is predominant in rehabilitation, the clinical guidelines have begun to recommend an interdisciplinary approach that considers patients needs and their families. Now-a-days, there is a gap on how to operationalize effective interventions responding to this paradigm. Objectives: To find evidence that sustains the development and assessment of outpatient neurorehabilitation approaches of people with brain injury and, to describe the possible operationalization methodologies of these. Methodology: Inductive and conceptual review of literature. Results: In Chilean Literature does not exist empirical evidence nor systematic developments on the foundations and effectiveness of outpatient rehabilitation programs for people with brain injury. International Literature describes three approaches: holistic, client centered, and goal-based. While such approaches can guide the team actions, the evidence of their effectiveness, based on expert criteria and small longitudinal studies and single case studies is still limited. Conclusions: For the development of a rehabilitation team identity, it is essential to determine the principles and approaches that support their work. Due to complexity and diversity of patients in the ambulatory phase, it is crucial that teams have clear foundations to guide the constant decision making. The evaluation of the effectiveness of ambulatory programs in Chile is a necessity; also it is to develop methodologies according to the nature of the phenomenon.
Assuntos
Humanos , Assistência Ambulatorial , Equipe de Assistência ao Paciente , Reabilitação/métodos , Lesões Encefálicas Traumáticas/reabilitação , Modelos TeóricosRESUMO
Autoimmune chronic lymphocytic thyroiditis appears in two forms, goitrous and atrophic. The evidence available is not enough to prove that the goitrous precedes the atrophic form, but immunogenetic analysis suggests that they may be distinct entities. The distribution of HLA class II alleles DRB1* and DQB1* was verified in patients from the region of Campinas, São Paulo, Brazil with both forms of thyroiditis. Ninety-one patients with primary hypothyroidism through autoimmune thyroiditis were classified as goitrous - 54 patients, 42.27 +/- 11.72 years old, having had hypothyroidism for 8.57 +/- 6.63 years - or atrophic - 37 patients, 42.72 +/- 12.01 years old, hypothyroidism for 6.73 +/- 4.07 years. The distribution of class II alleles was determined, DRB1* and DQB1* were genotyped after purifying DNA blood samples using the DNAzol technique, and the low-resolution PCR-SSP system was utilized for determination of generic alleles. Chi-square and Fisher's exact test were utilized to compare the distribution frequency of HLA alleles and the significant p-values were subjected to Bonferroni correction. We have demonstrated that the DRB1*04 allele is associated with autoimmune thyroiditis, and that there are genotypic differences regarding the presentation forms with a strong association between DRB1*04 and DQB1*03 and the atrophic form only.
Assuntos
Alelos , Antígenos HLA-DQ/genética , Antígenos HLA-DR/genética , Hipotireoidismo/genética , Glândula Tireoide/imunologia , Tireoidite Autoimune/genética , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Atrofia , Doenças Autoimunes/genética , Brasil , Distribuição de Qui-Quadrado , Feminino , Frequência do Gene , Predisposição Genética para Doença , Bócio/genética , Bócio/imunologia , Cadeias beta de HLA-DQ , Cadeias HLA-DRB1 , Teste de Histocompatibilidade , Humanos , Hipotireoidismo/imunologia , Masculino , Pessoa de Meia-Idade , Razão de Chances , Polimorfismo Genético , Valores de Referência , Linfócitos T/imunologia , Tireoidite Autoimune/classificação , Tireoidite Autoimune/imunologiaRESUMO
OBJECTIVE: To describe the response to exercise of normal subjects and patients with chronic obstructive pulmonary disease (COPD) in Bogota, Colombia (altitude: 2640 m; atmospheric pressure: 560 mm Hg) and compare it with data published on COPD patients at sea level. Healthy people increase their minute ventilation to attenuate hypoxemia (PaCO2: 30 mm Hg; PaO2: 63 mm Hg). MATERIAL AND METHOD: A descriptive study was carried out on healthy subjects and COPD patients. Exercise limitation was determined by an incremental test on a cycle ergometer. RESULTS: The study enrolled 16 healthy subjects and 25 COPD patients (forced expiratory volume in 1 second: 43.3% [SD 13%]). Minute ventilation at rest was greater in COPD patients compared with healthy subjects, it was not adequately sustained during exercise, and there was a reduction in peak oxygen uptake (53.0% [15%]). At peak exercise, inspiratory capacity decreased (-0.62 [0.34] L), the ratio of minute ventilation to maximal voluntary ventilation increased, and severe hypoxemia occurred (PaO2: 49.9 [9.9] mm Hg). There was significant correlation between hypoxemia and the percentage of predicted peak oxygen uptake (r=0.60), leg fatigue (r=-0.62), percentage of predicted peak inspiratory capacity (r=0.61), and the percentage of predicted peak tidal volume (r=0.49). Minute ventilation at rest was shown to be higher, there was a greater reduction in the inspiratory capacity during exercise, and hypoxemia was more severe at rest and during exercise for patients with COPD in Bogota, compared with those at sea level. CONCLUSIONS: Patients with COPD living in Bogota were shown to have lower tolerance to exercise evidenced by ventilatory limitation and severe hypoxemia. Increased minute ventilation at rest, greater reduction in inspiratory capacity, and severity of hypoxemia during exercise were the main differences between COPD in Bogota and at sea level.
Assuntos
Altitude , Exercício Físico/fisiologia , Doença Pulmonar Obstrutiva Crônica/fisiopatologia , Ventilação Pulmonar/fisiologia , Gasometria , Colômbia , Teste de Esforço , Feminino , Humanos , Medidas de Volume Pulmonar , Masculino , Pessoa de Meia-Idade , Oxigênio/sangue , Doença Pulmonar Obstrutiva Crônica/diagnóstico , Fenômenos Fisiológicos Respiratórios , Descanso , EspirometriaRESUMO
El tratamiento abdominal se ha convertido en un problema emergente y dentro de éste el órgano más frecuentemente lesionado este riñón. El objetivo de nuestro trabajo fue caracterizar epidemiológicamente y analizar la conducta terapéutica de los traumas renales ingresados a nuestro servicio. Se analizaron retrospectivamente las fichas clínicas de 42 pacientes ingresados por traumatismo abdominal complicado en el Servicio de Urgencia del Hospital San Borja Arriarán entre los años 1984 a 2001. De los pacientes con trauma renal se analizó la información referente a exámenes clínicos e imagenológicos, su clasificación, su tratamiento y complicaciones. De los 42 traumas abdominales hubo 13 casos con compromiso renal, los exámenes realizados fueron análisis de orina en todos los casos, ecografía renal en 9,TAC en 6 UIV en 5 angiografía renal en un caso. La frecuencia de las lesiones fue: 5 Grado 2, 1 Grado 3, 5 Grado 4, 1 Grado 5. La relación hombre mujer fue de 3,6: 1 con un promedio de edad de 9 años 6 meses, los mecanismos de lesión más frecuentes fueron caídas de altura, golpe directo y atropello (con 4 casos cada uno), el manejo fue expectante en 10 casos y de resolución quirúrgica de urgencia en 3. En 3 pacientes en que se mantuvo conducta expectante debió realizarse una cirugía electiva por complicaciones. Se realizaron 2 nefrectomías y una heminefrectomía. El promedio de estadía hospitalaria fue de 15 días, siendo 31 para los pacientes con cirugía y de 6 días para los que no quirúrgicos. Nuestro trabajo concuerda con la literatura en que el riñón más frecuentemente lesionado en los traumas abdominales. Existe una clara diferencia en cuanto al sexo, siendo el grupo más afectado los hombres entre 7 a 12 años. Dentro de los exámenes realizados, la ecografía es uno de los más solicitados. Se observa a través de los años analizados una tendencia hacia un manejo conservador para las lesiones renales.
Assuntos
Humanos , Criança , Rim , Neoplasias AbdominaisRESUMO
Se analizan y discuten los diferentes conceptos de extensión por prevención de la preparación que se han desarrollado desde 1881 hasta 1999. La introducción de nuevos conocimientos en diversas áreas de la odontología hicieron que los postulados de Black en ese particular se cuestinaran tanto en la enseñanza como en la práctica clínica
Assuntos
Preparo da Cavidade Dentária/tendências , Odontologia Preventiva , Restauração Dentária Permanente/tendências , Fissuras Dentárias , Preparo da Cavidade Dentária/história , Restauração Dentária Permanente/históriaRESUMO
Infecçöes bacterianas crônicas ou de repetiçäo däo início e perpetuam o ciclo vicioso de lesäo das vias aéreas através da estimulaçäo dos mecanismos inflamatórios, desencadeada pelos produtos bacterianos e pela invasäo bacteriana recorrente. As exacerbaçöes agudas de bronquite crônica(EABC) säo caracterizadas por quadro abrupto de tosse,aumento da dispnéia e aumento no volume de escarro produzido. Em dois terços ou mais dos casos típicos de EABC säo isolados patógenos bacterianos. O patógeno predominante é o H. influenzae, o qual se encontra nitidamente associado ao círculo vicioso de inflamaçäo e infecçäo de repetiçäo. Entre outros patógenos comumente encontrados se incluem Moraxella catarrhalis, muitas das quais resistentes às aminopenicilinas devido à produçäo de ß-lactamase e, também, Streptococcus pneumoniae, em relaçäo aos quais se tem observado aumento no número de cepas resistentes à penicilina e macrolídeos, em âmbito mundial...
Assuntos
Humanos , Antibacterianos/uso terapêutico , Bronquite , Pneumopatias Obstrutivas/tratamento farmacológico , Cefalosporinas/uso terapêutico , Macrolídeos/uso terapêutico , Penicilinas/uso terapêuticoRESUMO
El hematoma subdural agudo se debe habitualmente a un traumatismo de cráneo y ocasionalmente a la rotura de un aneurisma o una malformación vascular en el espacio subdural.Se presenta el caso de un paciente con cefalea súbita intensa que posteriormente deteriora su sensorio.No tuvo historia de traumatismo de cráneo.Se efectuó el diagnóstico tomográfico de hematoma subdural agudo y en el acto quirúrgico se indentificó un sangrado activo arterial sin malformación asociada.La entidad hematoma subdural agudo espontáneo de origen arterial es revisada
Assuntos
Humanos , Adulto , Hematoma Subdural/diagnóstico , Tomografia Computadorizada por Raios X , Ruptura Espontânea/diagnósticoRESUMO
El hematoma subdural agudo se debe habitualmente a un traumatismo de cráneo y ocasionalmente a la rotura de un aneurisma o una malformación vascular en el espacio subdural.Se presenta el caso de un paciente con cefalea súbita intensa que posteriormente deteriora su sensorio.No tuvo historia de traumatismo de cráneo.Se efectuó el diagnóstico tomográfico de hematoma subdural agudo y en el acto quirúrgico se indentificó un sangrado activo arterial sin malformación asociada.La entidad hematoma subdural agudo espontáneo de origen arterial es revisada
Assuntos
Humanos , Adulto , Hematoma Subdural/diagnóstico , Ruptura Espontânea/diagnóstico , Tomografia Computadorizada por Raios XRESUMO
OBJECTIVE: To investigate if exposure to firewood smoke and other indoor pollutants is a potential risk factor for obstructive airways disease (OAD) among women in Bogota in whom cigarette smoking and other known risk factors may not be the most frequent. DESIGN AND SETTING: We conducted a hospital-based case-control study to identify risk factors for OAD among women in Bogota. An interview was conducted using a modified questionnaire recommended by the American Thoracic Society for epidemiologic studies. PATIENTS: We compared 104 OAD cases with 104 controls matched by hospital and frequency matched by age. ANALYSIS: The odds ratio (OR) was used as the basic statistic to evaluate risk. Multivariate analysis (MA) was conducted by the Mantel-Haenszel procedure and by logistic regression. MAIN RESULTS: Univariate analysis showed that tobacco use (OR = 2.22; p < 0.01), wood use for cooking (OR = 3.43; p < 0.001), passive smoking (OR = 2.05; p = 0.01), and gasoline use for cooking (OR = 0.52; p = 0.02) were associated with OAD. Trends for years of tobacco use and years of wood cooking were present (p < 0.05). After MA, variables remained significant except gasoline use. CONCLUSIONS: This study showed that among elderly women of low socioeconomic status in Bogota, woodsmoke exposure is associated with the development of OAD and may help explain around 50% of all OAD cases. The role of passive smoking remains to be clarified. This work may set the basis for interventional studies in similar settings.
Assuntos
Poluentes Atmosféricos/efeitos adversos , Poluição do Ar em Ambientes Fechados/efeitos adversos , Exposição Ambiental , Pneumopatias Obstrutivas/etiologia , Fumaça/efeitos adversos , Madeira , Adulto , Fatores Etários , Idoso , Estudos de Casos e Controles , Colômbia , Culinária , Feminino , Gasolina/efeitos adversos , Humanos , Modelos Logísticos , Pessoa de Meia-Idade , Análise Multivariada , Razão de Chances , Fatores de Risco , Fumar/efeitos adversos , Classe Social , Inquéritos e Questionários , Poluição por Fumaça de Tabaco/efeitos adversosRESUMO
This paper describes the early lexical development of a group of 328 normal Spanish-speaking children aged 0;8 to 2;7. First the development and structure of a new parent report instrument, Inventario del Desarollo de Habilidades Communicativas is described. Then five studies carried out with the instrument are presented. In the first study vocabulary development of Spanish-speaking infants and toddlers is compared to that of English-speaking infants and toddlers. The English data were gathered using a comparable parental report, the MacArthur Communicative Development Inventories. In the second study the general characteristics of Spanish language acquisition, and the effects of various demographic factors on that process, are examined. Study 3 examines the differential effects of three methods of collecting the data (mail-in, personal interview, and clinic waiting room administration). Studies 4 and 5 document the reliability and validity of the instrument. Results show that the trajectories of development are very similar for Spanish- and English-speaking children in this age range, that children from varying social groups develop similarly, and that mail-in and personal interview administration techniques produce comparable results. Inventories administered in a medical clinic waiting room, on the other hand, produced lower estimates of toddler vocabulary than the other two models.
Assuntos
Desenvolvimento Infantil , Linguagem Infantil , Desenvolvimento da Linguagem , Pré-Escolar , Comparação Transcultural , Feminino , Hispânico ou Latino , Humanos , Lactente , Masculino , Estados Unidos/etnologia , Comportamento Verbal , VocabulárioAssuntos
Humanos , Masculino , Feminino , Embolização Terapêutica/métodos , Hemoptise/terapia , Doença Aguda , Adolescente , Adulto , Idoso , Angiografia Digital , Embolização Terapêutica/instrumentação , Resumo em Inglês , Hemoptise/diagnóstico por imagem , Pessoa de Meia-Idade , Radiografia Intervencionista/métodos , Recidiva , Indução de Remissão , Falha de TratamentoAssuntos
Humanos , Masculino , Feminino , Embolização Terapêutica/métodos , Hemoptise/terapia , Doença Aguda , Adolescente , Adulto , Idoso , Angiografia Digital , Resumo em Inglês , Embolização Terapêutica/instrumentação , Hemoptise , Pessoa de Meia-Idade , Recidiva , Indução de Remissão , Radiografia Intervencionista/métodos , Falha de TratamentoRESUMO
We studied 18 patients, 9 women and 9 men, ranging in age from 18 to 76 years. The main symptom was hemoptysis and the underlying pathology was tuberculosis, actinomycosis, lung cancer, metastatic carcinoma and systemic lupus. Nonsurgical patients, with recurrent hemoptysis or massive bleeding were selected. The embolization substances were spongostan, avitene (R) and PVA; they all produce temporary as well as persistent hemostasis. The procedure was successful in 16 patients. In two patients the embolization was not performed, one for technical reasons and the other because the vessel to be treated was the source of an anterior spinal artery. It is considered that the endovascular treatment constitutes an alternative for hemoptysis, even during the acute period, mainly in the management of nonsurgical patients.
Assuntos
Embolização Terapêutica/métodos , Hemoptise/terapia , Doença Aguda , Adolescente , Adulto , Idoso , Angiografia Digital , Embolização Terapêutica/instrumentação , Feminino , Hemoptise/diagnóstico por imagem , Humanos , Masculino , Pessoa de Meia-Idade , Radiografia Intervencionista/métodos , Recidiva , Indução de Remissão , Falha de TratamentoRESUMO
We studied 18 patients, 9 women and 9 men, ranging in age from 18 to 76 years. The main symptom was hemoptysis and the underlying pathology was tuberculosis, actinomycosis, lung cancer, metastatic carcinoma and systemic lupus. Nonsurgical patients, with recurrent hemoptysis or massive bleeding were selected. The embolization substances were spongostan, avitene (R) and PVA; they all produce temporary as well as persistent hemostasis. The procedure was successful in 16 patients. In two patients the embolization was not performed, one for technical reasons and the other because the vessel to be treated was the source of an anterior spinal artery. It is considered that the endovascular treatment constitutes an alternative for hemoptysis, even during the acute period, mainly in the management of nonsurgical patients.