RESUMO

Formation of Venecuelan equine encephalomyelitis virus (VEE) aggregates induced by UV-light has been studied. The high doses of UV-irradiation induced the protein-protein cross-links resulting in formation of fast sedimenting viral structures. The latter structures are supposed to be presented by the aggregates of several virions linked by the UV-light induced RNA-protein and protein-protein covalent bonds. The lesions in the fine structure of virion envelope was registered by the electron microscopy technique.

Assuntos

Vírus da Encefalite Equina Venezuelana/efeitos da radiação , Raios Ultravioleta , Vírus da Encefalite Equina Venezuelana/metabolismo , Vírus da Encefalite Equina Venezuelana/ultraestrutura , Substâncias Macromoleculares , Microscopia Eletrônica , RNA Viral/metabolismo , RNA Viral/efeitos da radiação , Proteínas Virais/efeitos da radiação , Proteínas Virais/ultraestrutura