RESUMO

Oleoma is a non-allergic, foreign body type granulomatous reaction. It appears as response to oily exogenous substances injected to the dermis or subcutis for aesthetical purposes. Treatment for localized lesions is surgical. When they are multiple, steroids may show some result. Newer therapeutic possibilities are being introduced and colchicine constitutes an alternative that is financially accessible and safe in moderate doses for certain dermatological illnesses. We present two women with oleoma on the legs treated with oral colchicine. This option was due to the extension of the clinical picture, which would not have a good surgical outcome. There was significant improvement in one patient, while we had to interrupt the medication in the other because of side effects.

RESUMO

A doença de Grover, ou dermatose acantolítica transitória, consiste em uma dermatose papulovesiculosa pruriginosa, caracterizada histologicamente por acantólise. A maior parte dos casos está representada por homens brancos acima de 40 anos de idade. Não existeetiologia conhecida, mas o calor e o suor excessivos são descritos com frequência como fatores desencadeantes ou agravantes. O diagnóstico é feito por suspeição clínica e confirmado pela biópsia das lesões cutâneas. Neste estudo é relatado o caso de um paciente de 53 anos de idade, com doença de Grover associada à infestação por Sarcoptes scabiei.

Grover?s disease, or transient acantholytic dermatosis, consists of a papulovesicular pruritic dermatosis histologically characterized by acantholysis. Most cases are represented by white men above 40 years of age. There is no known etiology; however, heat and excessive sweating are frequently described as triggering or aggravating factors. The diagnosis is made by clinical suspicion and confirmed by biopsy of cutaneous lesions. In this study the case of a 53-year-old patient is reported with Grover?s disease associated with infestation by Sarcoptes scabiei.