1.
Acta Haematol
; 92(3): 154-6, 1994.
Artigo
em Inglês
| MEDLINE
| ID: mdl-7871957
RESUMO
We report a case of Felty's syndrome in which neutropenia was corrected by a short-term treatment with recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF, 5 micrograms/kg/day s.c. for 14 days). Absolute neutrophil counts rose from 0.1 to 2.2 x 10(9)/l and remained > 1.0 x 10(9)/l 8 weeks after discontinuation of the GM-CSF therapy. A flare-up of arthritis and a decrease in platelet counts were observed.
Assuntos
Síndrome de Felty/tratamento farmacológico , Fator Estimulador de Colônias de Granulócitos e Macrófagos/administração & dosagem , Neutropenia/tratamento farmacológico , Adulto , Eosinófilos/efeitos dos fármacos , Síndrome de Felty/sangue , Síndrome de Felty/complicações , Feminino , Humanos , Contagem de Leucócitos/efeitos dos fármacos , Neutropenia/sangue , Neutropenia/etiologia , Neutrófilos/efeitos dos fármacos , Proteínas Recombinantes/administração & dosagem , Indução de Remissão , Fatores de Tempo
2.
Rev Hosp Clin Fac Med Sao Paulo
; 44(4): 167-70, 1989.
Artigo
em Português
| MEDLINE
| ID: mdl-2696069
RESUMO
Aplastic anemia is a condition characterized by bone marrow hipoplasia and pancytopenia. Various etiologic agents are related to the acquired form of this disease but in many cases the causative agents remain obscure. Severe aplastic anemia has been treated by immunosuppression and allogeneic marrow transplantation.