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This study aimed to analyze the knowledge of 335 dentistry students about prescription and use of drugs. The participants were divided into two groups: Group I -composed of 136 students in the last period/semester of the Dentistry course and Group II -composed of 199 students who had recently completed the discipline of Pharmacology/Therapeutics Applied to Dentistry (second semester of graduation). Students answered a questionnaire with 19 closed questions divided into three blocks of interest, Block A (5questions about their academic background); Block B (4 questions about legislation and drug prescription) and Block C (10 questions about common prescription in cases of increased risk due to comorbidities in Dentistry). The instrument was validated afterthe application of three pilot studies in 60 volunteer students who had recently completed the Pharmacology/Therapeutics Applied to Dentistry discipline. The results allowed classifying the level of knowledge as bad, moderate, good or excellent according to the stratification adopted by the authors. Most of the students interviewed were female, 22 years old. According to the results, 70% of the participants stated that the duration of the Pharmacology/Therapeutics Applied to Dentistry course was insufficient for them to feel safe when prescribing medications. The data presented showed that in block "B" only 19% of the students knew who was responsible for the prescription document. Additionally, 57% identified the mandatory items on an antimicrobial prescription. The successful rate of block "C" showed that the participants presented reasonable knowledge of most of the questions related to indication and prescription of medication both in regular and risky situations in Dentistry. The student's average knowledge regarding the indication and prescription of drugs reveals a problem in academic qualification related to drug therapy. It also highlights the need for continuing education of dental surgeons (AU).
Este estudio tuvo como objetivo analizar los conocimientos de 335 estudiantes de odontología sobre la prescripción y uso de medicamentos. Los participantes fueron divididos en dos grupos: Grupo I -compuesto por 136 estudiantes del último período/semestre de la carrera de Odontología y Grupo II -compuesto por 199 estudiantes que habían finalizado recientemente la disciplina de Farmacología/Terapéutica Aplicada a la Odontología (segundo semestre de pregrado). Los estudiantes respondieron un cuestionario con19 preguntas cerradas divididas en tres bloques de interés, Bloque A (5 preguntas sobre su formación académica); Bloque B (4 preguntas sobre legislación y prescripción de medicamentos) y Bloque C (10 preguntas sobre prescripción común en casos de mayor riesgo por comorbilidades en Odontología). El instrumento fue validado luego de la aplicación de tres estudios piloto en 60 estudiantes voluntarios que habían finalizado recientemente la disciplina Farmacología/Terapéutica Aplicada a la Odontología. Los resultados permitieron clasificar el nivel de conocimientos como malo, moderado, bueno o excelente según la estratificación adoptada por los autores. La mayoría de los estudiantes entrevistados eran mujeres, de 22 años. Según los resultados, el 70% de los participantes afirmó que la duración del curso de Farmacología/Terapéutica Aplicada a la Odontología fue insuficiente para sentirse seguros al prescribir medicamentos. Los datos presentados mostraron que en el bloque "B" sólo el 19% de los estudiantes sabían quién era el responsable del documento de prescripción. Además, el 57% identificó los artículos obligatorios en la prescripción de antimicrobianos. La tasa de éxito del bloque "C" demostró que los participantes presentaron conocimientos razonables en la mayoría de las cuestiones relacionadas con la indicación y prescripción de medicamentos tanto en situaciones habituales como de riesgo en Odontología. El conocimiento medio del estudiante sobre la indicación y prescripción de medicamentos revela un problema en la calificación académica relacionada con la farmacoterapia. También destaca la necesidad de una educación continua de los cirujanos dentistas (AU).
Este estudo teve como objetivo analisar o conhecimento de 335 estudantes de Odontologia sobre prescrição e uso de medicamentos. Os participantes foram divididos em dois grupos: Grupo I -composto por 136 alunos do último período/semestre do curso de Odontologia e o Grupo II -composto por 199 alunos que haviam concluído recentemente a disciplina de Terapêutica Medicamentosa/Farmacologia (segundo semestre da graduação). Os estudantes responderam a um questionário com 19 perguntas fechadas dividido emtrês blocos de interesse, Bloco A (5 perguntas sobre sua formação acadêmica); Bloco B (4 perguntas sobre legislação e prescrição de medicamentos) e Bloco C (10 perguntas sobre prescrição comum em casos de risco aumentado por comorbidade em Odontologia). Oinstrumento foi validado após a aplicação de três estudos piloto em 60 alunos voluntários que recentemente haviam concluído a disciplina de Terapêutica Medicamentosa/Farmacologia. Os resultados permitiram classificar o nível de conhecimento como ruim, moderado, bom ou excelente de acordo com a estratificação adotada pelos autores. A maioria dos alunos entrevistados era do sexo feminino, com 22 anos de idade. De acordo com os resultados, 70% dos participantes afirmaram que a duração da disciplina Farmacologia/Terapêutica Aplicada à Odontologia foi insuficiente para que se sentissem seguros ao prescrever medicamentos. Os dados apresentados mostraram que no bloco "B" apenas 19% dos alunos sabiam quem é o responsável pelo documento de prescrição. Além disso, 57% identificaram os itens obrigatórios em uma prescrição antimicrobiana. O índice de sucesso do bloco "C" mostrou que os participantes apresentaram conhecimento razoável envolvendo as questões sobre indicação e prescrição de medicamentos tanto em situaçõesregulares quanto em situações de risco na Odontologia. O conhecimento médio dos alunos quanto à indicação e prescrição de medicamentos revela um problema na formação acadêmica relacionada à terapia medicamentosa (AU).
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Humanos , Masculino , Feminino , Adolescente , Adulto , Farmacologia , Prescrições de Medicamentos , Estudantes de Odontologia , Conhecimentos, Atitudes e Prática em Saúde , Distribuição de Qui-Quadrado , Inquéritos e Questionários , Uso de MedicamentosRESUMO
OBJECTIVE: To compare the effect of photobiomodulation (PBM) and transcutaneous electrical nerve stimulation (TENS) in the treatment of burning mouth. MATERIALS AND METHODS: Randomized clinical trial of 25 patients with burning mouth treated by TENS (n=12) and PBM (n=13). The patients were treated weekly for 8 weeks. Two-factor ANOVA was used to determine whether the two interventions promoted significant differences in symptoms (measured with a visual analogue scale), unstimulated salivary flow, xerostomia, and dysgeusia between T0 (baseline), T1 (after the 4th treatment session), T2 (after the 8th treatment session), and T3 (30 days after the end of treatment). RESULTS: Intragroup comparison of VAS scores for pain showed a significant difference between T0xT1, T0xT2, and T0xT3 in the TENS group and between T0xT2 and T0xT3 in the PBM group (pË0.001). Intergroup comparison of VAS scores for pain between T2xT3 showed a better response to PBM than to TENS (p=0.003). Patients of the TENS group showed an increase in salivary flow between T1 and T2 (p=0.052). There were no expressive variations in xerostomia or dysgeusia in the two groups analyzed. CONCLUSION: TENS and PBM were effective in reducing the symptoms of burning mouth during and after treatment. The PBM group showed a better response during follow-up. TRIAL REGISTRATION: This clinical trial was registered at http://clinicaltrials.gov (Number: NCT05816200). CLINICAL RELEVANCE: TENS was found to be a safe and effective therapy for burning mouth. Trial registration number (TRN) and date of registration: This clinical trial was registered at http://clinicaltrials.gov (Number: NCT05816200; date: May 08, 2023).
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Introduction: Stevens-Johnson syndrome (SJS) is caused by a delayed immune response triggered by the association of genetic and environmental factors. This reaction can be mediated mainly by some drugs. Objective: The purpose of this article is to report the case of a patient with SJS associated with carbamazepine. Case report: A man was hospitalized complaining of odynophagia, whitish plaques in the mouth and swelling of the lips. Clinical examination revealed ulcerated and erosive lesions involving the buccal mucosa, lips, tongue and hard palate. The lips were swollen and with hemorrhagic crusts. Papular and purplish-colored lesions were observed on the skin. The patient reported that the lesions started 10 days ago, coinciding with the start of carbamazepine use. The diagnosis of SJS was established based on clinical information and the patient treated with support therapy. Conclusion: SJS is a clinical condition that affects the oral mucosa and can be triggered by the use of carbamazepine. (AU)
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Humanos , Masculino , Adulto , Carbamazepina , Síndrome de Stevens-Johnson , Hipersensibilidade a Drogas , Hipersensibilidade , Mucosa BucalRESUMO
MYH9 disease is a rare genetic disorder in which there is a mutation in the gene for the non-muscle myosin heavy chain IIA. It initially causes macrothrombocytopenia followed by other clinical manifestations. When the patient reaches adulthood, he can develop chronic kidney failure. Thus, the risk of suffering a hemorrhage, difficulty in repairing and, infections increases in individuals with this disease. In addition, the use of drugs in these patients should be carefully evaluated. An adult patient sought dental care with a complaint associated with a tooth with advanced dental caries. He had severe thrombocytopenia (7000 platelets/mm3 ), hearing loss, and chronic kidney failure. The diagnosis of MYH9 disease was confirmed through genotyping. After clinical examination, extraction was planned. Local and systemic procedures were used to prevent hemorrhage, especially postoperatively. Although the patient had an infection at the surgical wound site and no episode of postoperative bleeding, the repair process occurred normally. The purpose of this article is to report the surgical management of a patient with MYH9 disease.
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Cárie Dentária , Perda Auditiva Neurossensorial , Falência Renal Crônica , Trombocitopenia , Adulto , Masculino , Humanos , Cadeias Pesadas de Miosina/genética , Proteínas Motores Moleculares/genética , Perda Auditiva Neurossensorial/genética , Perda Auditiva Neurossensorial/cirurgia , Perda Auditiva Neurossensorial/complicações , Trombocitopenia/complicações , Trombocitopenia/genética , Mutação , Falência Renal Crônica/complicaçõesRESUMO
BACKGROUND/PURPOSE: Actually, many individuals have opted for the vegetarian diet. The objective of this study was to evaluate the impact of the vegetarian diet on the oral epithelium through cytopathology. METHODS: Oral smears of the tongue and buccal mucosa of 60 adult subjects (30 vegetarians and 30 controls) were collected. Smears were analyzed morphologically and for three morphometric variables: nucleus area (NA), cytoplasm area (CA) and nucleus/cytoplasm ratio. RESULTS: Vegetarians were classified as ovolactovegetarian (53.3%), vegans (30%) and strict vegetarians (16.7%). The NA and CA of the epithelial cells of vegetarian individuals were smaller when compared to controls both in the region of the buccal mucosa and tongue. However, there was no statistically significant difference according to the Student's t-test. For the NA/CA ratio, cells in the oral mucosa region were larger for vegetarians compared to controls. For the tongue, both groups had the same value and the Mann-Whitney U test confirmed that there is no difference between the groups for this cytomorphometric variable. RESULTS: Vegan individuals had a smaller (but not larger) area of CA when compared to controls for the tongue (vegan = 2604.2 ± 179.2 versus control = 3256.7 ± 463.8 p = 0.013). Most smears showed normal epithelial cells and some individuals had changes of an inflammatory nature, mainly in the tongue. CONCLUSION: Despite the small sample size, the results of this study raise the hypothesis that the vegetarian diet (especially the vegan diet) can compromise the thickness of the oral epithelium of the tongue.
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Dieta Vegetariana , Mucosa Bucal , Adulto , Dieta , Dieta Vegana , Humanos , Veganos , VegetarianosRESUMO
This study aimed to analyze Facebook's use as a pedagogical tool for teaching didactics for graduate students in Dentistry. Seventy-two adult students participated in this study. These students attended theoretical classes, developed practical activities by Facebook, and evaluated the course through a questionnaire. Tasks were analyzed concerning the following criteria: time torespond to assignments and whether they have been finished or not. Additionally, post type and students' reactions to posts were also evaluated. Forty-three (59.8%) students have considered Facebook as a good pedagogical resource. Only 5 (22%) students answered that they had some difficulty in responding to the assignments of the course through Facebook. Most students completed their tasks through Facebook. However, in general, most students only fulfilled the assignments close to the deadline. The main reactions of the students were likes and comments. Despite its limitations, Facebook seems to be a great pedagogical resource to be inserted in post-graduate education. In addition, the students still show little participation even being in the virtual environment of Facebook (AU).
O objetivo deste estudo foi analisar a utilização do Facebook como ferramenta pedagógica para o ensino de didática para alunos de graduação em Odontologia. Setenta e dois alunos adultos participaram da pesquisa. Esses alunos participaram de aulas teóricas, desenvolveram atividades práticas no Facebook e avaliaram o curso por meio de um questionário. As tarefas foram analisadas em relação aos seguintes critérios: tempo para responder às atividades e se elas foram realizadas de forma completa ou incompleta. Além disso, os tipos de postagens e as reações dos alunos às postagens também foram avaliados. Quarenta e três (59,8%) alunos consideraram o Facebook um bom recurso pedagógico. Apenas 5 (22%) alunos responderam que tiveram alguma dificuldade em responder às atividades do curso pelo Facebook. A maioria dos alunos concluiu suas tarefas por meio do Facebook. No entanto, em geral, a maioria dos alunos só cumpriu astarefas perto do prazo. As principais reações dos alunos foram curtidas e comentários. Apesar de suas limitações, o Facebook parece ser um grande recurso pedagógico a ser inserido na pós-graduação. Além disso, os alunos ainda se mostram pouco participativos mesmo estando no ambiente virtual do Facebook (AU).
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Humanos , Masculino , Feminino , Adulto , Estudantes de Odontologia/psicologia , Educação em Odontologia , Mídias Sociais/instrumentação , Redes Sociais Online , Inquéritos e Questionários/estatística & dados numéricos , Interpretação Estatística de Dados , Aprendizagem Baseada em Problemas/métodosRESUMO
Epilepsy is defined as a group of symptoms resulting from several neuronal complications ranging from changes in consciousness and motor activity to sensory phenomena and aberrant behaviors. This health problem has been associated with cases of stigma that can seriously affect the patient's quality of life. This study's main objectivewas to investigate the knowledge and attitudes regarding the treatmentof patients diagnosed with epilepsy by undergraduate dentistry students. The methodology was based on applyinga structured questionnaire with 17 close-endedquestions that evaluated information such as sociodemographic data, knowledge about epilepsy and social tolerance. The sample consisted of 397 students enrolled in the Dentistry course atFederal University of Paranáand divided into: group 1, students attending the 1st to the 7th semester of the course,and group 2, students in the last semester of the course. Group 1 students had more opportunities to care for patients with epilepsy than group 2. Most students expressed positive attitudes towardliving with people suffering from epilepsy and considered that they could not exercise certain professional activities. The question with the least number of correct answers dealt with the treatment of patients with the disease. Students' knowledge of epilepsy was low. However, the level of positive attitudes towardliving with this type of patient was considered high (AU).
A epilepsia é definida como um complexo de sintomas resultantes de diversas complicações neuronais que variam de alterações da consciência e da atividade motora até fenômenos sensoriais e comportamentos aberrantes. Esse problema de saúde tem sido associado a casos de estigma que podem repercutir seriamente na qualidade de vida do paciente. Este estudo teve por objetivo principal investigar o conhecimento e as atitudes em relação ao manejo de pacientes com diagnóstico de epilepsia dos estudantes de graduação do curso de Odontologia. A metodologia foi baseada na aplicação de um questionário estruturado com 17 perguntas fechadas que avaliaram informações como dados sociodemográficos, conhecimento sobre epilepsia e tolerância social. A amostra foi composta por 397 estudantes matriculados no curso de Odontologia da Universidade Federal do Paraná e dividida em: grupo 1, alunos cursando do 1º até o 7º semestre do curso e grupo 2, alunos do último semestre do curso. Os estudantes dogrupo 1 tiveram mais oportunidades para atender pacientes com epilepsia do que os do grupo 2. A maioria dos estudantes manifestou atitudes positivas em relação ao convívio com pessoas que sofrem de epilepsia e considerou que elas não poderiam exercer determinadas atividades profissionais. A questão com menor número de acertos tratava do tratamento de pacientes com a doença. O conhecimento dos estudantes em relação à epilepsia foi baixo. Porém, o nível de atitudes positivas em relação ao convívio com esse tipo de paciente foi considerado alto (AU).
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Humanos , Masculino , Feminino , Estudantes de Odontologia , Conhecimentos, Atitudes e Prática em Saúde , Educação em Odontologia , Epilepsia/diagnóstico , Qualidade de Vida , Distribuição de Qui-Quadrado , Inquéritos e Questionários , Estatísticas não ParamétricasRESUMO
AIM: Lyophilized demineralized dentin matrix (LDDM) consists of a type 1 collagen complex matrix containing growth factors and no mineral crystals. Although the efficacy of LDDM for bone grafting is well known, there is limited evidence on the biological response to human lyophilized DDM. Therefore, the aim of this study was to evaluate the biological response of subcutaneous tissues in rats to powdered LDDM, mineral trioxide aggregate (MTA), and Biodentine implanted using polyethylene tubes. METHODS: Forty Wistar rats were divided into four groups (n = 10 each) depending on the experimental time intervals and were placed in polyethylene tubes containing LDDM, MTA, biodentine, and one empty control. After 3, 7, 15, and 30 observation days, the animals were sacrificed and quantitative and qualitative analysis of the subcutaneous tissue samples was carried out. The intensity of the inflammatory response was scored from 0 (no response) to 3 (severe response), and the data were statistically analyzed using ANOVA and Bonferroni tests (p < 0.05). RESULTS: All groups exhibited moderate inflammation after 3 and 7 days of observation, with presence of inflammatory infiltrate predominantly consisting of macrophages and angioblastic proliferation being observed. After 15 observation days, the control group exhibited mild inflammation and a predominance of fibroblasts, and this differed significantly from the remaining cement groups that exhibited moderate inflammation. After 30 days of observation, all groups exhibited a mild inflammatory response, predominance of fibroblasts, and a greater amount of collagen fibers. CONCLUSION: Within the limitations of this study, it can be concluded that LDDM exhibited an acceptable biological response similar to MTA and Biodentine in the subcutaneous tissues of rats.
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BACKGROUND: This study aimed to investigate the morphology and chemical composition of dental caries related to ionizing radiation (DCIR), an aggressive and progressive disease that affects dental hard tissues. MATERIALS AND METHODS: Eight human teeth with DCIR were paired with sixteen control teeth (8 teeth with conventional caries and 8 without caries) and included in this study. An analysis of the morphology of the lesions was performed using the following techniques: periapical radiography, cone beam computed tomography, computed microtomography, and scanning electron microscopy. The chemical composition was assessed using X-ray dispersive spectroscopy. RESULTS: There was more demineralization in DCIR lesions when compared to conventional dental caries, even though there was no cavitation in the cervical region of the teeth. The superficial roughness and topography of DCIR lesions were similar to those of healthy teeth. On the other hand, lesions of conventional dental caries showed greater surface and topographic irregularity when compared to DCIR and healthy teeth (p = 0.001). Calcium (Ca) and phosphorus (P) levels were lower in DCIR lesions when compared to controls. However, higher levels of carbon (C) have been observed in DCIR lesions. There was a greater loss of the mineral matrix in DCIR followed by conventional caries. The reduction in the mineral matrix (Ca and P) was compatible with the imaging patterns observed in teeth with DCIR and conventional caries. CONCLUSION: Despite their rapid evolution, DCIR presents an irregular, apparently intact surface with significant changes in the amount of Ca, P, and C.
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BACKGROUND: Schizophrenia (SCZ) presents complex challenges related to diagnosis and clinical monitoring. The study of conditions associated with SCZ can be facilitated by using potential markers and patterns that provide information to support the diagnosis and oral health. METHODS: The salivary composition of patients diagnosed with SCZ (nâ¯=â¯50) was evaluated and compared to the control (nâ¯=â¯50). Saliva samples from male patients were collected and clinical parameters were evaluated. The concentration of total proteins and amylase were determined and salivary macro- and microelements were quantified by ICP OES and ICP-MS. Exploratory data analysis based on artificial intelligence tools was used in the investigation. RESULTS: There was a significant increase in the salivary concentrations of Al, Fe, Li, Mg, Na, and V, higher prevalence of caries (pâ¯<â¯0.001), periodontal disease (pâ¯<â¯0.001), and reduced salivary flow rate (pâ¯=â¯0.019) in SCZ patients. Also, samples were grouped into six clusters. As, Co, Cr, Cu, Mn, Mo, Ni, Se, and Sr were correlated with each other, while Fe, K, Li, Ti, and V showed the highest concentrations in the samples distributed in the clusters with the highest association between SZC patients and controls. CONCLUSIONS: The results obtained indicate changes in salivary flow, organic composition, and levels of macro- and microelements in SCZ patients. Salivary concentrations of Fe, Mg, and Na may be related to oral conditions, higher prevalence of caries, and periodontal disease. The exploratory analysis showed different patterns in the salivary composition of SCZ patients impacted by associations between oral health conditions and the use of medications. Future studies are encouraged to confirm the results investigated in this study.
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Metais/química , Saliva/química , Esquizofrenia/metabolismo , Oligoelementos/análise , Adolescente , Adulto , Idoso , Inteligência Artificial , Estudos de Casos e Controles , Humanos , Masculino , Espectrometria de Massas , Metais/metabolismo , Pessoa de Meia-Idade , Saúde Bucal , Saliva/metabolismoRESUMO
AIMS: The aim of the present study was to evaluate the taste perception in patients with upper complete dentures. METHODS AND RESULTS: One hundred seventy male and female patients (45-83 years old) upper denture wearers were evaluated for their gustatory function by the paper strips technique in relation to the four basic tastes. The taste test was performed with and without the presence of the denture on the palate. Through Shapiro-Wilk and Kolmogorov-Smirnov tests, the results were analyzed by their normal distribution. The t-test for paired samples was used to evaluate if there was a statistical difference on the taste perception and itself revealed that there is a significant difference (p < 0.01) when the taste perception was analyzed for the absence and presence of the prosthesis (alone and compared) (p < 0.01). The results revealed that patients with dentures had great difficulty to recognize the bitter taste, followed by the salty, sweet, and sour. CONCLUSION: The presence of the denture was able to modify the perception of taste when compared to its absence, especially for the bitter taste.
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Percepção Gustatória , Paladar , Idoso , Idoso de 80 Anos ou mais , Prótese Total , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , PalatoRESUMO
BACKGROUND: Saliva is a complex secretion produced daily by the salivary glands. Saliva consists mainly of water, enzymes, ions and amino acids and performs several important functions in oral health. OBJECTIVE: The aim of this study was to investigate the flow rate and concentrations of amylase and total proteins in the saliva of hospitalized patients due to AIDS complications. METHODS: Ninety-three men and women (20-64 years of age) were divided into two groups (46 HIV-infected patients and 47 controls) and had salivary flow rate and levels of amylase enzyme and total proteins evaluated. RESULT: The mean salivary flow rate was lower in individuals with HIV when compared to controls (P < 0.05). No significant difference between amylase enzyme levels and total proteins were observed in the saliva of patients with HIV infection when compared to controls. CONCLUSION: Individuals with HIV / AIDS infection (in hospital treatment) suffer no interference in levels of amylase and total salivary proteins, but they have significantly reduced salivary flow.
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Infecções por HIV/complicações , Soropositividade para HIV/complicações , Saliva/metabolismo , Proteínas e Peptídeos Salivares/metabolismo , Salivação/fisiologia , Xerostomia/complicações , alfa-Amilases/metabolismo , Adolescente , Adulto , Idoso , Amilases/análise , Amilases/metabolismo , Fármacos Anti-HIV/uso terapêutico , Terapia Antirretroviral de Alta Atividade/efeitos adversos , Estudos de Casos e Controles , Feminino , Infecções por HIV/sangue , Infecções por HIV/tratamento farmacológico , Soropositividade para HIV/tratamento farmacológico , Humanos , Masculino , Pessoa de Meia-Idade , Glândulas Salivares/metabolismo , Proteínas e Peptídeos Salivares/análise , Taxa Secretória/efeitos dos fármacos , Taxa Secretória/fisiologia , Xerostomia/etiologia , Adulto Jovem , alfa-Amilases/análiseRESUMO
AIMS: The aim of this study was to compare individuals with and without schizophrenia through the characteristics of the palate, such as width, length, depth, palate shape, and upper dental arch shape. METHODS AND RESULTS: The sample was divided into one case group (n = 45) and two control groups (n = 90; 45 individuals each group). Groups were paired by variables: sex, age, and malocclusion type. All analyses were performed on upper dental arch plaster models. All individuals were male and the mean age was 28.56 (SD: 7.82) years. The frequency of the malocclusion type observed was 54.1% (Class I), 22.2% (Class II), and 23.7% (Class III). Statistically significant difference was observed between the case and control groups for the variables palate shape (P = .004) and upper dental arch shape (P = .003). The case group had a higher frequency of the deep or grooved palate shape (57.8%) and parabolic dental arch shape (48.9%). There was no statistically significant difference for the palate width, length, and depth (P > .05). CONCLUSIONS: There was an evidence that the deep or grooved palate shape and parabolic dental arch shape are morphological characteristics of the palate in men with schizophrenia.
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Arco Dental , Má Oclusão , Palato , Esquizofrenia , Adulto , Humanos , Masculino , Maxila , Palato/anormalidadesRESUMO
AIMS: To assess dental maturation in children with amelogenesis imperfecta (AI) and compare their estimated dental age with the age of non-AI children. METHODS AND RESULTS: Panoramic radiographs of children with (n = 27) and without (n = 54) AI were retrospectively collected in the ratio of 1:2. The former consisted of case group, while the latter figured as control group. Both groups were paired by sex and age (P > .05). Dental maturation was assessed in each radiograph using Demirjian's staging technique and Willems' method. Intra- and interexaminer reproducibility reached >0.8. The mean estimated dental age in subjects with AI was 12.5 ± 2.69 years, while in subjects without AI it was 11.73 ± 2.48 years (P = .21). The comparison of mean chronological (12.26 ± 2.6 years) and estimated dental age (12.5 ± 2.69 years) in subjects with AI did not reveal statistically significant differences (P = .38). CONCLUSION: This study highlights the similarity of dental maturation between subjects with and without AI from the radiographic perspective of crown-root formation.
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Determinação da Idade pelos Dentes , Amelogênese Imperfeita , Estudos de Casos e Controles , Criança , Humanos , Radiografia Panorâmica , Reprodutibilidade dos Testes , Estudos RetrospectivosRESUMO
INTRODUCTION: Pulp stones are mineral structures that develop in the pulp tissue triggered by several clinical conditions. The exact biochemical process behind the occurrence of pulp stones is uncertain. This study aimed to perform a structural and crystallographic characterization of pulp stones and dentin from extracted human teeth. METHODS: The sample consisted of 13 erupted and unerupted permanent human teeth diagnosed with pulp stones. The teeth were analyzed with scanning electron microscopy with secondary and backscattered electrons, energy-dispersive spectroscopy, micro-Raman spectroscopy, micro-X-ray diffraction, and inductively coupled plasma atomic emission spectroscopy. RESULTS: The pulp stones revealed a heterogeneous morphology and structure compared with each other. Compared with the adjacent dentin, the pulp stones had a similar structure. From a chemical point of view, oxygen, calcium, carbon, and phosphorus were the most prevalent chemical elements in the inner part of the stones, whereas on the surface carbon, nitrogen, sulfur, chlorine, aluminum, potassium, zinc, copper, and lead were the most prevalent. Copper, iron, and zinc were higher in the stones than the dentin (P < .05). Statistically significant differences between the chemical structure of stones from erupted and unerupted teeth were not detected (P > .05). CONCLUSIONS: Pulp stones have structural and chemical properties that are similar to dentin. Variations in morphology are common.
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Calcificações da Polpa Dentária , Polpa Dentária , Calcificações da Polpa Dentária/diagnóstico por imagem , Cavidade Pulpar , Dentina , Humanos , Microscopia Eletrônica de VarreduraRESUMO
AIMS: This study aimed to investigate the morphology of the palate, palatal rugae pattern, and dental arch form in patients with schizophrenia. METHODS AND RESULTS: An observational case-control study was designed following the STROBE statement and checklist. The sample consisted of 132 patients (39 diagnosed with schizophrenia and 93 controls). Dental casts of the patients were classified based on the pattern of their palatal rugae, their dental arch form, and the area of their palate. The palatal rugae in patients with schizophrenia had a more random distribution and shape compared to the control group (P = .027). Oval dental arches were the most prevalent in both groups (P = .473). The palate area was slightly larger in the control group (3.2318 ± 0.549 mm2 ) compared with the group of patients with schizophrenia (3.060 ± 0.470 mm2 ) (P = .090). CONCLUSION: Palatal rugae pattern may feature as a potential minor physical anomaly for schizophrenia. Additional studies with alternative sampling and classification systems are necessary to understand this finding and its applications in practice.
Assuntos
Arco Dental , Esquizofrenia , Estudos de Casos e Controles , Humanos , Mucosa Bucal , Palato DuroRESUMO
BACKGROUND: This study investigated the association between sociodemographic, behavioral, oral health, variables of drug consumption, and the short version of the Oral Health Impact Profile (OHIP-14), in Southern Brazilian drug users. METHODS: In this cross-sectional study, 202 drug users aged 18 or over admitted for treatment at the Institute for Research and Treatment of Alcoholism (Instituto de Pesquisa e Tratamento do Alcoolismo -IPTA) from the municipality of Campo Largo, PR, Brazil, from 2012 to 2014, were involved. They answered a questionnaire and were examined by a calibrated researcher. Data were collected and bivariate (Chi-square test) and multivariate (logistic regression and Wald's test) analyses were performed. RESULTS: There was statistical difference (P<0.05) in bivariate analysis and the worst impacts were reported by non-whites, those who reported feeling metallic taste in mouth and tooth mobility, which use cigarettes for over 15 yr and consume more than 3 g of crack/day, with DMFT >10, and number of teeth in mouth ≤27. In the multivariate analysis, statistical difference remained, except for ethnicity (P=0.207). CONCLUSION: Self-perception of oral health was associated with the variables explored, which suggests the need for strategies focused on this population.
RESUMO
OBJECTIVE: To assess the genotoxicity and cytotoxicity produced by X-rays in the epithelium of the oral mucosa of infants exposed to panoramic radiography. METHODS: The sample consisted of 30 healthy children, 19 females and 11 males, ranging in age from 4 to 10 years (average of 7 years of age). Oral mucosa cells were collected by liquid-based cytology immediately before and after seven days following the exposure to panoramic radiography. Smears were processed and stained using the modified Feulgen Rossenbeck technique. Bud and broken egg nuclear projections, changes in the form of micronuclei, and genotoxic and cytotoxic changes of pyknosis, karyorrhexis and karyolysis were analyzed and quantified. RESULTS: The frequency of pyknosis, buds and broken eggs was significantly higher after exposure to X-rays (p<0.05), but there was no statistically significant difference regarding gender, as well as in the other changes studied. CONCLUSIONS: Exposure to X-rays emitted during submission to panoramic radiography may induce cell death in the epithelium of children's oral mucosa. No evidence was found for a significant genotoxic effect.
OBJETIVO: Analisar a genotoxicidade e a citotoxicidade produzidas por raios X no epitélio da mucosa oral de crianças durante a obtenção da radiografia panorâmica. MÉTODOS: A amostra foi constituída por 30 crianças saudáveis, sendo 19 do sexo feminino e 11 do masculino, com faixa etária de 4 a 10 anos (média de 7 anos de idade). As células epiteliais da mucosa oral foram coletadas por meio de citologia esfoliativa em base líquida imediatamente antes e após sete dias da obtenção da radiografia panorâmica. Os esfregaços foram processados e corados utilizando a técnica de Feulgen Rossenbeck modificada. Foram analisadas e quantificadas projeções nucleares dos tipos bud e broken egg, alterações genotóxicas na forma de micronúcleo e alterações citotóxicas dos tipos picnose, cariólise e cariorrexe. RESULTADOS: A frequência de picnose, bud e broken egg foi significativamente maior após a exposição aos raios X (p<0,05), porém não houve diferença estatisticamente significante em relação ao sexo, bem como nas demais alterações estudadas. CONCLUSÕES: A exposição aos raios X emitidos durante a obtenção da radiografia panorâmica pode induzir à morte celular no epitélio da mucosa oral de crianças. Não foi encontrado indício significativo de efeito genotóxico.
Assuntos
Dano ao DNA , Mucosa Bucal/citologia , Mucosa Bucal/efeitos da radiação , Radiografia Panorâmica/efeitos adversos , Criança , Pré-Escolar , Feminino , Humanos , MasculinoRESUMO
RESUMO Objetivo: Analisar a genotoxicidade e a citotoxicidade produzidas por raios X no epitélio da mucosa oral de crianças durante a obtenção da radiografia panorâmica. Métodos: A amostra foi constituída por 30 crianças saudáveis, sendo 19 do sexo feminino e 11 do masculino, com faixa etária de 4 a 10 anos (média de 7 anos de idade). As células epiteliais da mucosa oral foram coletadas por meio de citologia esfoliativa em base líquida imediatamente antes e após sete dias da obtenção da radiografia panorâmica. Os esfregaços foram processados e corados utilizando a técnica de Feulgen Rossenbeck modificada. Foram analisadas e quantificadas projeções nucleares dos tipos bud e broken egg, alterações genotóxicas na forma de micronúcleo e alterações citotóxicas dos tipos picnose, cariólise e cariorrexe. Resultados: A frequência de picnose, bud e broken egg foi significativamente maior após a exposição aos raios X (p<0,05), porém não houve diferença estatisticamente significante em relação ao sexo, bem como nas demais alterações estudadas. Conclusões: A exposição aos raios X emitidos durante a obtenção da radiografia panorâmica pode induzir à morte celular no epitélio da mucosa oral de crianças. Não foi encontrado indício significativo de efeito genotóxico.
ABSTRACT Objective: To assess the genotoxicity and cytotoxicity produced by X-rays in the epithelium of the oral mucosa of infants exposed to panoramic radiography. Methods: The sample consisted of 30 healthy children, 19 females and 11 males, ranging in age from 4 to 10 years (average of 7 years of age). Oral mucosa cells were collected by liquid-based cytology immediately before and after seven days following the exposure to panoramic radiography. Smears were processed and stained using the modified Feulgen Rossenbeck technique. Bud and broken egg nuclear projections, changes in the form of micronuclei, and genotoxic and cytotoxic changes of pyknosis, karyorrhexis and karyolysis were analyzed and quantified. Results: The frequency of pyknosis, buds and broken eggs was significantly higher after exposure to X-rays (p<0.05), but there was no statistically significant difference regarding gender, as well as in the other changes studied. Conclusions: Exposure to X-rays emitted during submission to panoramic radiography may induce cell death in the epithelium of children's oral mucosa. No evidence was found for a significant genotoxic effect.