RESUMO
O extrato aquoso de Stryphnodendron adstringens é tradicionalmente utilizado no Brasil como cicatrizante. Estudo clínico conduzido por seis meses teve por objetivo avaliar a eficácia de um medicamento na forma de pomada, contendo 3% de fitocomplexo fenólico de barbatimão na cicatrização de úlceras de decúbito. Foram submetidos ao protocolo clínico 27 pacientes apresentando um total de 51 úlceras, classificadas de acordo com a área e grau de profundidade (I a III) da lesão. Em média a cicatrização das lesões de grau I e II ocorreu num período de 3 a 6 semanas e as de grau III entre 10 e 18 semanas. Durante a realização do estudo 100% das lesões tratadas com o medicamento cicatrizaram completamente.
RESUMO
AIM: To compare a new root canal sealer based on Copaifera multijuga oil-resin (Biosealer) using three other established sealers (Sealer 26, Endofill and AH plus) in terms of their physicochemical properties. METHODOLOGY: The study was carried out according to the requirements of Specification Number 57 of the American Dental Association (ADA) and consisted of the following tests: setting time, flow, film thickness, dimensional stability, radiopacity and solubility/disintegration. Data were analysed statistically using anova and Tukey's test for multiple comparisons. The significance level was set at 5% for all analyses. RESULTS: Sealer 26 and AH Plus had the longest setting time (P < 0.05). All materials presented flow in with the ADA's guidelines. Regarding film thickness, Sealer 26 did not have a satisfactory performance, as it had a higher mean value than the maximum allowed by the ADA (0.05 mm), being significantly different from the other materials (P < 0.05), which had mean values for film thickness in accordance with the ADA's recommendations. Regarding the solubility and disintegration, only Endofill did not meet the ADA's specifications and presented the worst results of all materials (P < 0.05). Sealer 26 presented the greatest dimensional changes and differed significantly from all other sealers (P < 0.05). Biosealer had the lowest radiopacity values and was significantly different from the other sealers (P < 0.05). CONCLUSION: The experimental sealer based on Copaifera multijuga oil-resin presented satisfactory results in the physicochemical tests required by the ADA.
Assuntos
Fabaceae , Fitoterapia , Óleos de Plantas , Resinas Vegetais , Materiais Restauradores do Canal Radicular , Análise de Variância , Meios de Contraste , Teste de Materiais , Materiais Restauradores do Canal Radicular/química , Solubilidade , Estatísticas não Paramétricas , ViscosidadeRESUMO
The aim of this research was to evaluate the susceptibility profile of Pseudomonas spp. and the prevalence of bacterial samples isolated from horizontal surfaces surrounding wash-basins used by dentists in several adjoined consulting-rooms, at points next to and at a distance from the basin, before and after surgical procedures. Our results showed a high percentage of Gram-positive cocci and Gram-negative bacilli; 34.66% were Staphylococcus spp. and 30.12% were non-fermentative Gram-negative bacilli among which Pseudomonas spp. (40.90%) was the commonest genus. Analysis of the susceptibility profile of Pseudomonas spp. isolates by determining the minimal inhibitory concentration (MIC) of 14 antibiotics showed a great variation among the strains and high rates of resistance to cefazolin, ceftazidime and aztreonan. Of the 14 antibiotics tested, 59.03% were found to be active against all the environmental isolates. Strains were resistant to aztreonan (62.82%), while susceptibility to third generation cephalosporins was variable
Assuntos
Bactérias Gram-Negativas , Bactérias Gram-Negativas/isolamento & purificação , Bactérias Gram-Positivas , Bactérias Gram-Positivas/isolamento & purificação , Consultórios Odontológicos , Infecções por Pseudomonas/epidemiologia , Pseudomonas aeruginosaRESUMO
The work describes the biocompatibility and biodegradation studies of anionic collagen membranes casted form collagen gels collagen, that were selective hydrolyzed at the carboxyamide groups, as a function of the degree of cross-links induced by glutaraldehyde. Independently from the degree of cross-links, all membranes studied were characterized by a similar inflammatory response, inversely dependent on glutaraldehyde reaction time, that decreased from the time of the implant. Cell alterations, mineralization or contact necrosis were not observed in any of the membranes studied. Rates for membrane tissue biodegradation were directly related to glutaraldehyde reaction time, and ranged from 30 to periods longer than 60 days, associated with good biocompatibility. Although other properties must be considered, their use in the treatment of periodontal diseases, the biological behavior observed with the 8 h GA cross-linked membrane suggests that, anionic collagen membrane described in this work may be of potential use, not only in association with guided tissue regeneration technique for periodontal tissue reconstruction, but also in other collagen biomaterial applications where controlled biodegradability is required.
Assuntos
Materiais Biocompatíveis , Colágeno/química , Reagentes de Ligações Cruzadas , Glutaral , Membranas Artificiais , Tendões , Animais , Biodegradação Ambiental , Bovinos , Colágeno/farmacocinética , Estabilidade de Medicamentos , Géis , Temperatura Alta , Masculino , Próteses e Implantes , Ratos , TermodinâmicaRESUMO
The authors verified histologically in 20 no dentates patients, the influence of complete dentures on the hard palate mucosa. The patients were divided in two groups: I. Patients that never used complete dentures; II. Patients that were using complete dentures when this research was realized. New prosthesis were made for each one of the 20 patients. Immediately before they received the new prosthesis and ninety days after this, biopsies were realized. The circunferencial pieces of the hard palate mucosa were fixed in formol 10% and coloured with Hematoxylin/Eosin and Mallory's Tricomic for histomorphologic analysis and measuring of the stratum corneum of the epithelium. It was made the statistical analysis and the results showed that: 1. In normal conditions, the utilization of the full dentures produces the reduce of the thickness of the stratum corneum. This was more observed in Group I. 2. The range difference of the thickness of the stratum corneum between the first and the second biopsies in the groups I and II (4.86 microns and 2.18 microns) were not statistically significant. 3. With the use of complete dentures the stratum corneum of the epithelium showed tendence to parakeratinization.