RESUMO
OBJECTIVES: External validation of the 4C and NEWS2 scores for the prediction of in-hospital mortality in COVID-19 patients, and evaluation of its operational performance in two time periods: before and after the start of the vaccination program in Colombia. METHODS: Retrospective cohort in three high complexity hospitals in the city of Medellín, Colombia, between June 2020 and April 2022. RESULTS: The areas under the ROC curve (AUC) for the 4C mortality risk score and the NEWS2 were 0.75 (95% CI 0.73-0.78) and 0.68 (95% CI 0.66-0.71), respectively. For the 4C score, the AUC for the first and second periods was 0.77 (95% CI 0.74-0.80) and 0.75 (95% CI 0.71-0.78); whilst for the NEWS2 score, it was 0.68 (95% CI 0.65-0.71) and 0.69 (95% CI 0.64-0.73). The calibration for both scores was adequate, albeit with reduced performance during the second period. CONCLUSIONS: The 4C mortality risk score proved to be the more adequate predictor of in-hospital mortality in COVID-19 patients in this Latin American population. The operational performance during both time periods remained similar, which shows its utility notwithstanding major changes, including vaccination, as the pandemic evolved.
Assuntos
Vacinas contra COVID-19 , COVID-19 , Mortalidade Hospitalar , Vacinação , Humanos , Colômbia/epidemiologia , COVID-19/mortalidade , COVID-19/prevenção & controle , Estudos Retrospectivos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Vacinação/estatística & dados numéricos , SARS-CoV-2 , Curva ROC , Medição de Risco/métodos , AdultoRESUMO
OBJECTIVE: The purpose of this study was to evaluate the nasal septum and the depth of posterior palatal arch in the different facial vertical patterns using cone-beam computed tomography (CBCT). MATERIALS AND METHODS: A total of 143 CBCTs were analysed (53 normodivergents, 26 hypodivergents, and 64 hyperdivergents) using the software Real Scan 2.2. On the coronal view, the following measurements were taken, palatal interalveolar length (PIL), palatal arch depth (PAD), maxillopalatal arch angle (MPAA), septal vertical length (SVL), deviated septal length (DSL), and deviated septal curve angle (DSCA). Using the program Stata v16.0, we obtained the mean, standard deviation and median values. The identification of significant differences between facial biotypes was performed using the one-way ANOVA test and H of Kruskal-Wallis test, considering a significance level of 0.05. RESULTS: The hypodivergent group got the highest PIL and MPAA (49.6mm and 118.1° respectively), with statistically significant differences (P<0.05) between this group and the hyperdivergent group. Statistically significant differences were found by gender for the SNMeGo, PFH, AFH, and the relationship between the facial heights, where the males had the highest values. Additionally, PIL and SVL also had the highest values for males (48.8mm and 63.6mm respectively). CONCLUSIONS: Patients presenting with greater hyperdivergence have shorter interalveolar distances and smaller maxillopalatal arch angles.
Assuntos
Tomografia Computadorizada de Feixe Cônico , Palato , Face/diagnóstico por imagem , Humanos , Masculino , Septo Nasal/diagnóstico por imagemRESUMO
OBJECTIVE: Evaluate the height, thickness and cortical density of the palatal bone of adults with different vertical facial patterns using Cone-Beam Computed Tomography (CBCT). METHODS: This study analyzed 75 CBCTs of patients between 18 and 35 years old (45 men and 30 women). The CBCTs were classified into three groups based on their facial pattern: normodivergent, hypodivergent and hyperdivergent as determined from lateral cephalograms synthesized from the CBCTs. The height, cortical thickness and cortical density of the palatal bone were measured at 4, 8, 12, 16 and 20mm posterior to the incisive foramen, and at 3, 6 and 9mm lateral to the midpalatal suture. ANOVA with Tukey post-hoc tests were used for analysis of the data, at significance level of p< 0.05. RESULTS: The hypodivergent pattern had a significant difference and the greatest height and cortical thickness of the palatal bone, followed by the hyperdivergent and the normodivergent patterns. No significant differences were found in minimum and maximum values of cortical density. CONCLUSION: The palatal bone is a favorable anatomical area to install different orthodontic temporary anchorage devices (TADs), where individuals with the hypodivergent vertical facial pattern have a higher height and cortical thickness of the palatal bone, followed by the hyperdivergent pattern and finally the normodivergent pattern. No significant differences in the cortical density of the palatal bone in the three facial patterns were found.
Assuntos
Implantes Dentários , Procedimentos de Ancoragem Ortodôntica , Adolescente , Adulto , Tomografia Computadorizada de Feixe Cônico , Face , Feminino , Humanos , Masculino , Palato/diagnóstico por imagem , Palato/cirurgia , Adulto JovemRESUMO
ABSTRACT Objective: Evaluate the height, thickness and cortical density of the palatal bone of adults with different vertical facial patterns using Cone-Beam Computed Tomography (CBCT). Methods: This study analyzed 75 CBCTs of patients between 18 and 35 years old (45 men and 30 women). The CBCTs were classified into three groups based on their facial pattern: normodivergent, hypodivergent and hyperdivergent as determined from lateral cephalograms synthesized from the CBCTs. The height, cortical thickness and cortical density of the palatal bone were measured at 4, 8, 12, 16 and 20mm posterior to the incisive foramen, and at 3, 6 and 9mm lateral to the midpalatal suture. ANOVA with Tukey post-hoc tests were used for analysis of the data, at significance level of p< 0.05. Results: The hypodivergent pattern had a significant difference and the greatest height and cortical thickness of the palatal bone, followed by the hyperdivergent and the normodivergent patterns. No significant differences were found in minimum and maximum values of cortical density. Conclusion: The palatal bone is a favorable anatomical area to install different orthodontic temporary anchorage devices (TADs), where individuals with the hypodivergent vertical facial pattern have a higher height and cortical thickness of the palatal bone, followed by the hyperdivergent pattern and finally the normodivergent pattern. No significant differences in the cortical density of the palatal bone in the three facial patterns were found.
RESUMO Objetivo: Avaliar a altura, a espessura e a densidade cortical do osso palatino em adultos com diferentes padrões faciais verticais, utilizando a tomografia computadorizada de feixe cônico (TCFC). Métodos: O presente estudo analisou 75 TCFCs de pacientes com idades entre 18 e 35 anos (45 homens e 30 mulheres). As TCFCs foram classificadas em três grupos, de acordo com seus padrões faciais: normodivergentes, hipodivergentes e hiperdivergentes, conforme determinado na radiografia cefalométrica lateral reconstruída das TCFCs. Altura, espessura e densidade cortical do osso palatino foram aferidas a 4, 8, 12, 16 e 20 mm para posterior do forame incisivo e a 3, 6 e 9 mm lateralmente à sutura transpalatina. Os testes ANOVA e post-hoc de Tukey foram utilizados para análise dos dados, com nível de significância de p< 0,05. Resultados: O padrão hipodivergente apresentou uma diferença significativa e a maior altura e espessura cortical do osso palatino, seguido pelos padrões hiperdivergente e normodivergente. Nenhuma diferença estatisticamente significativa foi encontrada nos valores mínimos e máximos da densidade cortical. Conclusão: O osso palatino é uma área anatomicamente favorável para instalar diferentes dispositivos de ancoragem temporária. Indivíduos com padrão facial vertical hipodivergente apresentam maior altura e espessura cortical do osso palatino, seguido do padrão hiperdivergente e finalmente do padrão normodivergente. Não foi encontrada qualquer diferença significativa na densidade cortical do osso palatino entre os três padrões faciais.