Assuntos
Laparoscópios , Esterilização Tubária/instrumentação , Adulto , Feminino , Humanos , Pessoa de Meia-Idade , GravidezAssuntos
Laparoscopia , Métodos , Ciência , Adulto , Estudos de Avaliação como Assunto , Feminino , Humanos , Gravidez , Complicações na Gravidez , Esterilização TubáriaRESUMO
PIP: Prostaglandins (PGs) are unsaturated fatty acids with 20 carbon atoms; they are to be found in most human and animal tissues. There are 13 known PGs divided into 4 groups, E, F, A, and B. This article describes the use of PGF2alpha in a case of missed abortion. The patient, aged 22, was 9 months pregnant according to the date of last menstruation; the abdominal examination revealed uterine size corresponding to a 3 months' pregnancy; no fetal cardiac sign was present. Intravenous infusion of PGF2alpha was started with a dose of 25 mcg/minute for the first 30 minutes, then at a dose of 50 mcg/minute. Contractions started 1 hour 35 minutes after infusion, and continued irregularly. The patient aborted suddenly and completely at 10 hours 25 minutes after beginning of infusion; total quantity of PGF2alpha used was of 35 mg. A series of unpleasant side effects accompanied the procedure, starting at about 2 hours 10 minutes after starting PG infusion, precardial pain, nausea and vomiting; there was no diarrhea. The mechanism of PGs in inducing abortion is still unknown; administration can be intrauterine, besides intravenous, and, apparently, PGE1 is much more powerful than PGF2alpha.^ieng