RESUMO
Antibodies to human T lymphotropic virus type I has been detected in subjects of different human ethnicities all around the world. Etiological relationship between the virus and human diseases has been claimed by many investigators. Amplified and sequenced region of the long terminal repeat of human T lymphotropic virus type I obtained from nucleic acid extracted from serum samples of Japanese and Brazilian patients with cancer of uterine cervix and normal Brazilian subjects, all seropositives for the virus, showed minor genetic variations when compared to the Japanese prototype.
RESUMO
HTLV-I seroprevalences of 3.63% (02/55), 12.19% (10/82) and 13.88% (10/72) were demonstrated among Tiryio, Mekranoiti and Xicrin Amazonian Indians, respectively, by the Western blotting enzyme assay (WBEI). By indirect immunoelectron microscopy (IIEM), 2 Tiriyo, 9 Mekranoiti and 6 Xicrin Amerindians were reactive. Of 44 serum samples from Japanese immigrants, none reacted by any of the techniques before mentioned. One, 8 and 6 serum samples from Tiryio, Mekranoiti and Xicrin Indians, respectively, were both WBEI and IIEM positive. Our results strongly suggest that HTLV-I and/or an HTLV-I antigenic variant circulate (s) among populations living in the Amazon region of Brazil.
Assuntos
Anticorpos Anti-HTLV-I/sangue , Infecções por HTLV-I/etnologia , Infecções por HTLV-I/imunologia , Indígenas Sul-Americanos , Western Blotting , Brasil/epidemiologia , Humanos , Imuno-Histoquímica , Indígenas Sul-Americanos/estatística & dados numéricos , Japão/etnologia , Microscopia Imunoeletrônica , Prevalência , Estudos SoroepidemiológicosRESUMO
HTLV-I seroprevalences of 3.63% (02/55), 12.19% (10/82) and 13.88% (10/72) were demonstrated among Tiryio, Mekranoiti and Xicrin Amazonian Indians, respectively, by the Western blotting enzyme assay (WBEI). By indirect immunoelectron microscopy (IIEM), 2 Tiriyo, 9 Mekranoiti and 6 Xicrin Amerindians were reactive. Of 44 serum samples from Japanese immigrants, none reacted by any of the techniques before mentioned. One, 8 and 6 serum samples from Tiryio, Mekranoiti and Xicrin Indians, respectively, were both WBEI and IIEM positive. Our results strongly suggest that HTLV-I and/or an HTLV-I antigenic variant circulate (s) among populations living in the Amazon region of Brazil