RESUMO
Arcanobacterium haemolyticum was cultured from pharyngeal specimens obtained from 12 of 129 children with pharyngotonsillitis, some of whom had a scarlatiniform rash. This organism should be considered to be a cause of infections that are clinically similar to those caused by beta-hemolytic streptococci.
Assuntos
Corynebacterium/isolamento & purificação , Faringite/microbiologia , Escarlatina/microbiologia , Infecções Estreptocócicas/microbiologia , Streptococcus pyogenes , Tonsilite/microbiologia , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , Faringe/microbiologia , Estudos Prospectivos , Streptococcus pyogenes/isolamento & purificaçãoRESUMO
The 24 hr variations of plasma growth hormone (GH) and/or GH secretion provoked by oral glucose load or by insulin-induced hypoglycemia were studied in five microcephalic children. Low levels of GH and, especially, complete lack of secretory episodes were detected in three of the five children, two of whom were brothers. GH deficiency may constitute the principal or a contributing factor of impaired growth in some microcephalic children. A possible association between the cerebral abnomality and the pituitary hypofunction is suggested. An analogy is made between the present cases and the neuroendocrine complexes reported as Kallmann's and de Morsier's syndromes, respectively.