RESUMO
A 5 1/2 year-old boy was hospitalized with clinical and laboratory evidence of pancreatitis. Four days later the classic signs and symptoms of Kawasaki disease developed. This case suggests that Kawasaki disease should be included in the differential diagnosis of acute pancreatitis in children.
Assuntos
Síndrome de Linfonodos Mucocutâneos/diagnóstico , Pancreatite/diagnóstico , Doença Aguda , Pré-Escolar , Humanos , Masculino , Síndrome de Linfonodos Mucocutâneos/complicações , Pancreatite/complicaçõesAssuntos
Síndrome da Imunodeficiência Adquirida/complicações , Linfoma de Burkitt/complicações , Síndrome da Imunodeficiência Adquirida/microbiologia , Síndrome da Imunodeficiência Adquirida/patologia , Linfoma de Burkitt/microbiologia , Linfoma de Burkitt/patologia , Pré-Escolar , DNA , Herpesvirus Humano 4/isolamento & purificação , Humanos , Masculino , Hibridização de Ácido NucleicoRESUMO
A 5-month-old Amish infant boy with chronic granulomatous disease underwent bone marrow transplantation from his 5-year-old, histocompatible brother after a preconditioning regimen of busulfan 2 mg/kg/day for 4 days, followed by cyclophosphamide 50 mg/kg/day for 4 days. At the time of bone marrow transplantation, he was free of infection, and remained so throughout the course of the transplant. He was engrafted promptly, with complete reversal of the neutrophil function defect and no sign of graft-versus-host disease. This was followed by loss of the erythroid graft and deterioration in neutrophil function over a period of 9 months. Sixteen months after transplantation, he is free of infection and growing normally, with essentially no evidence for neutrophil engraftment.