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1.
Ultrason Sonochem ; 109: 106997, 2024 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-39032370

RESUMO

This study aimed to investigate the effect of ultrasound treatment times (30 min and 60 min) and levels of quinoa protein (QPE) addition (1 % and 2 %) on the quality of Chinese style reduced-salt pork meatballs, commonly known as lion's head. The water-holding capacity (WHC), gel and rheology characteristics, and protein conformation were assessed. The results indicated that extending the ultrasound treatment time and elevating the quinoa protein content caused conspicuous improvements (P<0.05) in the cooking yield, WHC, textural characteristics, color difference, and salt-soluble protein (SSP) solubility of the meatballs. Furthermore, the structural alterations induced by the ultrasound treatment combined with quinoa protein addition included enhancement in ß-sheet, ß-turn, and random coil structure contents, along with a red-shift in the intrinsic fluorescence peak. Additionally, the storage (G') and loss modulus (G'') of the raw meatballs significantly enhanced (P<0.05), indicating a denser gel structure in parallel with the microstructure. In conclusion, the findings demonstrated that ultrasound combined with quinoa protein enhanced the WHC and texture properties of Chinese style reduced-salt pork meatballs by improving SSP solubility.


Assuntos
Chenopodium quinoa , Proteínas de Plantas , Carne de Porco , Animais , Chenopodium quinoa/química , China , Culinária , Manipulação de Alimentos/métodos , Produtos da Carne/análise , Proteínas de Plantas/química , Reologia , Solubilidade , Ondas Ultrassônicas , Água/química , Carne de Porco/análise
2.
Oncotarget ; 8(5): 8818-8824, 2017 Jan 31.
Artigo em Inglês | MEDLINE | ID: mdl-27732566

RESUMO

GOAL: To share our experience of extra-levator abdominoperineal excision (ELAPE) for low rectal cancer, focusing on perineal repair with biological mesh. METHODS: We retrospectively analyzed medical records of all patients with low rectal cancer who underwent the ELAPE procedure using biological mesh for perineal repair at the Gastrointestinal Surgery of Nanjing Drum Power Hospital between January 2013 and September 2015. All patients were closely followed up to now. RESULTS: A total of 17 patients underwent ELAPE for low rectal cancer was screened. Of these, 15 patients had primary rectal cancer, 1 had local recurrent rectal cancer, and 1 had malignant melanoma. All patients underwent ELAPE successfully without intestinal perforation and got stage I healing in perineum wound without incision infection, dehiscence, cystocele perinealis, urethral dysfunction or intestinal obstruction. Perineum wound hematoma developed in just one patient and had successful percutaneous drainage in one week. During the follow-up, there was no recurrence, perineal hernia, sexual dysfunction, urinary retention, or bowel obstruction. Two patients described slight pain in the sacrococcygeal region without special handling. CONCLUSION: ELAPE is applicable to low rectal cancer. Biological mesh reconstruction of perineal defect seems to be safe and effective, with high patient compliance.


Assuntos
Diafragma da Pelve/cirurgia , Procedimentos de Cirurgia Plástica/instrumentação , Neoplasias Retais/cirurgia , Telas Cirúrgicas , Adulto , Idoso , Idoso de 80 Anos ou mais , China , Desenho de Equipamento , Feminino , Humanos , Masculino , Prontuários Médicos , Pessoa de Meia-Idade , Diafragma da Pelve/patologia , Complicações Pós-Operatórias/etiologia , Procedimentos de Cirurgia Plástica/efeitos adversos , Neoplasias Retais/patologia , Estudos Retrospectivos , Fatores de Tempo , Resultado do Tratamento , Cicatrização
3.
Asian Pac J Cancer Prev ; 15(8): 3659-65, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24870774

RESUMO

To assess inhibition mechanisms of a Phellinus igniarius (PI) extract on cancer, C57BL/6 mice were orally treated with PI extractive after or before implanting H22 (hepatocellular carcinoma ) or B16 (melanoma) cells. Mice were orally gavaged with different doses of PI for 36 days 24h after introduction of H22 or B16 cells. Mice in another group were orally treated as above daily for 42 days and implanted with H22 cells on day 7. Then the T lymphocyte, antibody, cytokine, LAK, NK cell activity in spleen, tumor cell apoptosis status and tumor inhibition in related organs, as well as the expression of iNOS and PCNA in tumor tissue were examined. The PI extract could improve animal immunity as well as inhibit cancer cell growth and metastasis with a dose-response relationship. Notably, PI's regulation with the two kinds of tumor appeared to occur in different ways, since the antibody profile and tumor metastasis demonstrated variation between animals implanted with hepatocellular carcinoma and melanoma cells.


Assuntos
Agaricales/imunologia , Anticorpos/efeitos dos fármacos , Carcinoma Hepatocelular , Citocinas/efeitos dos fármacos , Neoplasias Hepáticas , Melanoma Experimental , Linfócitos T/efeitos dos fármacos , Animais , Anticorpos/imunologia , Apoptose/efeitos dos fármacos , Linhagem Celular Tumoral/transplante , Proliferação de Células/efeitos dos fármacos , Citocinas/imunologia , Células Matadoras Ativadas por Linfocina/efeitos dos fármacos , Células Matadoras Ativadas por Linfocina/imunologia , Células Matadoras Naturais/efeitos dos fármacos , Células Matadoras Naturais/imunologia , Camundongos , Camundongos Endogâmicos C57BL , Óxido Nítrico Sintase Tipo II/efeitos dos fármacos , Óxido Nítrico Sintase Tipo II/imunologia , Antígeno Nuclear de Célula em Proliferação/efeitos dos fármacos , Antígeno Nuclear de Célula em Proliferação/imunologia , Linfócitos T/imunologia , Ensaios Antitumorais Modelo de Xenoenxerto
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