RESUMO
Surveys for respiratory virus antibodies in the Jamaican population have shown that adenovirus, respiratory syncytical virus and parainfluenza types 1 and 3 virus antibodies are acquired early in life. The incidence of haemagglutination-inhibiting antibodies to parainfluenza viruses increases rapidly with age and almost all adults possess parainfluenza type 3 antibody, usually in high titre. Parainfluenza type 1 antibodies are only slightly less common. Complement-fixing antibodies to the adenovirus group were also observed to increase in incidence with age. Complement-fixing antibody to respiratory syncytial virus was less common in Jamaican sera than antibody to the other respiratory viruses described here. The highest titres were observed in the youngest age-group. (Summary)
Assuntos
Humanos , Picornaviridae , Adenovírus Humanos , Vírus Sinciciais Respiratórios , Anticorpos Antivirais , Jamaica , Soros ImunesRESUMO
The results presented in this paper described a survey for hemagglutination-inhibiting antibodies to one type C and 2 type B influenza viruses in Jamaica sera. Antibodies to all 3 strains were found to be very common and the distribution by age of influenza B antibodies indicates that infections by the type B viruses occur in Jamaica primarily in the 5-to 9-year and 10- to 14 year age groups. A fairly widespread immunity to influenza B infection is evident in early adult life. The incidence and titer levels of hemagglutination-inhibiting antibodies to type C influenza virus increase throughout life. Primary infections is acquired during childhood and the increasing antibody titer levels with age suggest that reinfections are not uncommon. (AU)
Assuntos
Humanos , Pré-Escolar , Criança , Adolescente , Adulto , Pessoa de Meia-Idade , Idoso , Anticorpos/análise , Influenza Humana/epidemiologia , Fatores Etários , Testes de Inibição da Hemaglutinação , JamaicaRESUMO
The incidence and level of hemagglutination-inhibiting antibodies to 4 group A infleunza viruses in the population of Jamaica has shown that there is an approximately similar age distribution of antibodies to the different infleunza strains as has been encountered else-where. Antibody titres to A/Swine/1976/31 were highest in sera from older Jamaicans; antibodies titres to A1/Fort Manmouth/1/47 were maximal in the younger segment of the population and antibody titres to A/Puerto Rico/8/34 reached their highest levels in sera from intermediate age groups. The greatest incidences and levels of hemagluttination-inhibiting antibody in almost all age groups were observed against infleunza A2/Jamaica/2/63, a locally recovered type A2 strain.(Summary)
Assuntos
Humanos , Pré-Escolar , Criança , Adolescente , Adulto , Pessoa de Meia-Idade , Idoso , Anticorpos/análise , Influenza Humana/epidemiologia , Fatores Etários , Testes de Inibição da Hemaglutinação , Testes de Hemaglutinação , Soros Imunes , Jamaica , SuínosRESUMO
A survey of respiratory viruses and their antibodies in the Caribbean island of Jamaica has revealed that infleunza A, B and C viruses, parainfleunza type 1 and 3 viruses, respiratory syncytial virus and several types of adenovirus are causing respiratory infections in the Jamaican population. Respiratory virus infections were detected in Jamaica more frequently in the cooler months of the year, October through March, than in the warmer months. Adenoviruses were observed to be causing infections at all times of the year, but some evidence that parainfleunza type 1 infections are occurring at intervals only was obtained. Almost all infections by respiratory syncytial virus were obtained in infants and young children with severe lower respiratory tract disease.(Summary)
Assuntos
Humanos , Pré-Escolar , Criança , Adolescente , Masculino , Feminino , Infecções por Adenoviridae/epidemiologia , Infecções por Enterovirus/epidemiologia , Infecções por Herpesviridae/epidemiologia , Influenza Humana/epidemiologia , Infecções por Orthomyxoviridae/epidemiologia , Infecções Respiratórias/etiologia , Fatores Etários , Testes de Fixação de Complemento , Testes de Inibição da Hemaglutinação , Jamaica , Testes de Neutralização , /epidemiologia , Estações do Ano , Cultura de VírusRESUMO
This thesis describes a survey for respiratory viruses and their antibodies carried out at the Department of Microbiology, U. W. I., Mona from January, 1964 to June, 1966. The thesis is designed to show that representatives of the newer groups of viruses known to be associated with respiratory infections in humans are present in Jamaica, and to give indication of the prevalence of these viruses and their epidemiological behaviour in a tropical area. Two different approaches were made to the problem. Specimens from over 500 patients of ll ages and both sexes, suffering from both mild and severe respiratory infections were examined for the presence of respiratory viruses and their antibodies. Virus infection was detected in 67 (12.14 percent ) of these patients. Members of all the major groups of respiratory viruses, except rhinoviruses, were cultivated and serological conversions to many of them were also observed. Infections in children were found to be fairly common. Secondly, a series of surveys for antibodies to respiratory viruses in the general population were undertaken. Particular attention was paid to group A influenza viruses and their epidemic behaviour. Antibodies to type A2/Jamaica/2/63 influenza virus were widespread in the population, and there was a definite age-distribution of haemagglutination-inhibiting antibodies to certain other influenza strains. Antibodies to type C influenza virus were very common in the population of Jamaica. Antibodies to the parainfluenza viruses were also not infrequent in the sera of Jamaicans and evidence was obtained to show that these viruses and also respiratory syncytial virus caused frequent infections in infants and young children. Similarly, adenovirus antibodies were found to be acquired by the population at an early age (AU)
Assuntos
Humanos , Lactente , Criança , Adulto , Infecções Respiratórias/etiologia , Vírus/isolamento & purificação , Sorologia , Anticorpos Antivirais/isolamento & purificação , Testes de Inibição da Hemaglutinação , Testes de Fixação de Complemento , Testes de Neutralização , /isolamento & purificação , Gammainfluenzavirus/isolamento & purificação , /isolamento & purificação , Vírus Sinciciais Respiratórios/isolamento & purificação , Adenovírus Humanos/isolamento & purificação , Jamaica , Clima , Fatores EtáriosRESUMO
Several viral agents were involved. Influenza A and B were isolated during epidemic periods, and there have been recent isolations of Adenovirus, para-influenza and Respiratory Syncytial viruses from clinical cases (AU)
Assuntos
Humanos , Infecções Respiratórias , Sistema Respiratório , Viroses/etiologia , Jamaica/epidemiologiaRESUMO
A brief report on the isolation in Jamaica of five strains of Adenovirus, since February 1964, included a description of the techniques being used routinely, details of the Adenoviruses so far isolated and studied, together with some indication of other work being carried out in the field of respiratory virology in Jamaica (AU)