RESUMO

Leprosy is a chronic disease with clinical presentations according to the immunologic spectrum. Lepromatous form is the most advanced, with the highest transmissibility and risk of causing disabilities. Lucio's phenomenon is a rare manifestation among lepromatous patients with a rapid and severe evolution and high mortality. It is difficult to differentiate from ulcerative/necrotic erythema nodosum leprosum and has no consensus on how it should be treated. This article is a qualitative review of the literature after the introduction of multidrug therapy, aiming to bring consensus related to the clinical, laboratory and histopathological diagnostic criteria of the disease and its management.

Assuntos

Eritema Nodoso , Hanseníase Virchowiana , Hanseníase Multibacilar , Hanseníase , Quimioterapia Combinada , Eritema Nodoso/diagnóstico , Eritema Nodoso/terapia , Humanos , Hansenostáticos/uso terapêutico , Hanseníase/diagnóstico , Hanseníase/tratamento farmacológico , Hanseníase Virchowiana/diagnóstico , Hanseníase Virchowiana/tratamento farmacológico , Hanseníase Virchowiana/patologia , Hanseníase Multibacilar/tratamento farmacológico

Assuntos

Linfócitos B/patologia , Líquen Plano Bucal/imunologia , Líquen Plano Bucal/patologia , Idoso , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade