RESUMO
The patients reviewed in this study are thirty individuals with acute amoebic hepatic abscess. They were given tinidazol, two grams a day in one dose, for three days, with the object of ascertaining if this would be adequate treatment and without important side effects. The clinical diagnosis was confirmed by X-rays of the thoraz and abdomen, laboratory studies and liver scans. This latter as well as the laboratory tests were repeated at 10 and 20 days. Several of the patients were considered to be gravely ill. In 43% of the patients there was hepatomegaly grade II or II, in 30% there was jaundice, in 64% the abscess was very large and in 30% there were several abscesses. In keeping with the guide lines previously agreed on, 28 patients were cured, or that is 93%. There were no important side effects.
Assuntos
Abscesso Hepático Amebiano/tratamento farmacológico , Nitroimidazóis/uso terapêutico , Tinidazol/uso terapêutico , Doença Aguda , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Tinidazol/efeitos adversos , Tinidazol/farmacologiaRESUMO
To know the natural history and the several clinical manifestations of amyloidosis, were reviewed retrospectively 44 cases at the Hospital General, Centro Médico Nacional, I.M.S.S. We found the secondary type in 79 per cent, primary shape in 9 per cent and 2 per cent associated with multiple myeloma. The frequency was similar in both sexes and was greater between the fifth and sixth decade of life; 34 per cent of the patients were diabetic; the symptomatology corresponded in 90 per cent of the cases to the main pathology, and only 9.9 per cent of the cases it was secondary to the amyloidosis itself; the alterations of laboratory test were not specific. The organs involved in the cases of primary amyloidosis were: spleen (100 per cent), kidney (80 per cent), heart (80 per cent), digestive tract (60 per cent), and lung (60 per cent). In the secondary shape: spleen (56 per cent), liver (41 per cent), adrenals (23 per cent) and kidney (11 per cent). Death could generally be adscribed to intercurrent pathology.