RESUMO

Penetration of antibiotic preparations (gentamicin, neomycin, silver sulfadiazine, mupirocin) through Omiderm, a synthetic wound covering, was tested in vitro and in 5 patients with full-thickness burns who had undergone tangential excision and split-thickness skin grafting. All antibiotic preparations tested penetrated both meshed and unmeshed Omiderm. Omiderm did not affect the zones of inhibition of antimicrobial activity as compared with controls.

Assuntos

Antibacterianos/farmacocinética , Queimaduras/tratamento farmacológico , Poliuretanos/normas , Transplante de Pele/normas , Absorção/efeitos dos fármacos , Administração Tópica , Antibacterianos/administração & dosagem , Bandagens , Queimaduras/cirurgia , Estudos de Avaliação como Assunto , Humanos , Permeabilidade/efeitos dos fármacos