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Vascular ; 19(2): 89-96, 2011 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-21489934

RESUMO

This study evaluated the arterial response to cobalt-chromium stents with and without polymer coating (Camouflage®, Hemoteq AG, Wuerselen, Germany) implanted in pigs. Cobalt-chromium balloon-expandable stents (4 × 16 mm) were implanted in the common carotid arteries of nine pigs. Histological analysis of endothelialization, inflammation and injury was performed one month later. All stents were successfully deployed, and all but one animal survived the 30 study days. All arteries were patent. Endothelialization was nearly complete in most sections of all carotid stents in both groups. There were mild inflammatory infiltrate and mild-to-moderate injury, which were associated with the stent shafts and not significantly different between groups. Our findings suggest that, in porcine carotid arteries, the histological response to balloon-expandable cobalt-chromium stents coated with polymer (Camouflage®, Hemoteq AG) is similar to the response to non-coated cobalt-chromium stents.


Assuntos
Artérias Carótidas , Materiais Revestidos Biocompatíveis , Reestenose Coronária/prevenção & controle , Stents Farmacológicos , Heparina/uso terapêutico , Polímeros/uso terapêutico , Animais , Artérias Carótidas/patologia , Ligas de Cromo/uso terapêutico , Materiais Revestidos Biocompatíveis/uso terapêutico , Modelos Animais de Doenças , Endotélio Vascular/patologia , Desenho de Prótese , Stents , Suínos
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