RESUMO
La pérdida ósea en el sector anterior, ya sea por un defecto horizontal, vertical o combinado, actualmente es un desafío, no sólo por la integración del implante, sino por la estética involucrada. Entre las técnicas de regeneración ósea que permiten solucionar estos defectos, cabe destacar la técnica de expansión de crestas. Se presenta el caso de una paciente de 58 años con reborde atrófico, que se sometió a la expansión de crestas con colocación simultánea de implantes en sector anterior, con xenoinjerto previo a técnica de expansión de crestas con piezoeléctrico, colocación simultánea de implantes Narrow Connection SLActive Straumann. Se logró ganancia ósea y estabilidad primaria de los implantes, sin complicaciones. En escenarios seleccionados, la técnica de expansión de crestas de manera predecible permite ganancia de hueso horizontal adecuada, el éxito de los implantes con tasa de supervivencia y mínimas complicaciones intra y postoperatorias (AU)
Bone loss in the anterior sector, both a horizontal, vertical or combined defect is a challenge today; not only for the integration of the implant but also the aesthetic involved. There are techniques of bone regeneration that help us to solve this type of defects, among them we should highlight the crest expansion technique. We present the case of a 58-year-old patient with atrophic flange, who underwent the expansion of crests with simultaneous placement of implants in the anterior sector, with xenograft prior to the piezoelectric crest expansion technique, Simultaneous placement of Narrow Connection SLActive Straumann implants, bone gain and primary stability of the implants were obtained, without complications. In selected scenarios, the crest expansion technique could be considered a predictable approach that demonstrates a high implant survival rate, adequate horizontal bone gain, and minimal intra- and postoperative complications (AU)
Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Implantação Dentária Endóssea/métodos , Aumento do Rebordo Alveolar/métodos , Osteotomia/métodos , Piezocirurgia/métodos , XenoenxertosRESUMO
Se trata de paciente femenino de 22 años de edad, en quien se realizó una restauración en un molar siguiendo la filosofía de mínima intervención desde el diagnóstico hasta la obturación con un material bioactivo. Los objetivos del tratamiento fueron devolver la funcionalidad y estética de dicho molar, pero sobre todo brindar una protección a largo plazo mediante la liberación y recarga de iones de calcio, fosfato y flúor proporcionado por el material bioactivo (AU)
t is about a female patient of twenty-two years, in which a restoration was made in a molar following the philosophy of minimal intervention from diagnosis to filling with a bioactive material. The objectives of the treatment were to restore the functionality and aesthetics, but mainly to provide long-term protection through the release and recharge of calcium, phosphate and fluoride ions provided by the bioactive material used (AU)
Assuntos
Humanos , Feminino , Adulto , Materiais Biocompatíveis/uso terapêutico , Resinas Compostas/uso terapêutico , Restauração Dentária Permanente/instrumentação , Cárie Dentária/terapia , Dente Molar/lesõesRESUMO
Abstract A new cohort, known as ''Generation Z'', is nowadays studying Health Careers. These students were born between 1996 and 2012, and currently at year 2022, have between 18 and 26 years. It is necessary to comprehend their characteristics and behaviors, for a better understanding of how they learn, what do they expect from education and how to improve their academic development and potential. Generation Z is considered as the most diverse, and it requires a closer mentorship from teachers, who must be ready to help students to manage their time and resources efficiently. It is worth mentioning that Gen Z information about their professional performance is still preliminary, because they are currently studying their University programs. Thus, it will be interesting to further analyze the behavior of Generation Z in Dental Education.
Abstract Una nueva cohorte generacional, conocida como ''Generación Z'', se encuentra estudiando las Licenciaturas en el área de la Salud. Estos estudiantes nacieron entre los años de 1996 y 2012, y actualmente al año 2022, tienen entre 18 y 26 años. Es necesario comprender sus características y sus conductas, para tener un mejor entendimiento de cómo aprenden, qué esperan de la educación, y cómo se podría mejorar su desarrollo académico y su potencial. La Generación Z es conocida como la más diversa, y requiere de una mentoría cercana por parte de los profesores, quienes deben estar listos para ayudar a los estudiantes a manejar el tiempo y los recursos eficientemente. Es importante mencionar que la información referente al desempeño profesional de la Generación Z es aún preliminar, dado que actualmente están cursando sus programas universitarios. Por tanto, será interesante seguir analizando el comportamiento de la Generación Z en la Educación Odontológica.
Assuntos
Humanos , Relação entre Gerações , Educação em Odontologia/métodos , Intervalo entre GeraçõesRESUMO
Introduction: Neuromuscular deprogramming reduces the main symptoms such as pain by 70 to 90 percent in patients with temporomandibular dysfunction, but little information is available on the effect on quality of life and sleep. Objective: Determine the effect of neuromuscular deprogramming on quality of life and sleep in patients with temporomandibular dysfunction. Methods: 55 patients with temporomandibular dysfunction were included who were neuromuscularly deprogrammed (29 women and 26 men), with an average age of 34.9 ± 16.5 years. At the beginning and end of neuromuscular deprogramming, surveys were applied to assess the level of chronic pain, perception of quality of life related to oral health, perceived stress, quantity and quality of life, anxiety and depression. Results: In 37 patients (68 percent) pain was identified on examination, and it was confirmed in the chronic pain survey. The quality of life perception score was correlated with low sleep quality (r = 0.39; p = 0.008); pain score (r = 0.48; p = 0.003); anxiety (r = 0.55; p = 0.003) and depression (r = 0.41; p = 0.006). Neuromuscular deprogramming reduced patient-reported pain levels from 9.9 to 2.9 (p = 0.001), the percentage of patients with poor sleep quality from 60 percent to 29 percent (p < 0.0001), the quality of life score from 40.7 to 23.8 (p = 0.03), and perceived stress levels from 22.1 to 19.1 (p = 0.002). Conclusions: In patients with temporomandibular dysfunction, neuromuscular deprogramming reduces the level of pain. It is related to better perception in quality of life, higher quality of sleep and decreases perceived stress.
Introducción: La desprogramación neuromuscular reduce los síntomas principales como el dolor de 70 a 90 por ciento en los pacientes con disfunción temporomandibular, pero se dispone de escasa información sobre el efecto en la calidad de vida y sueño. Objetivo: Determinar el efecto de la desprogramación neuromuscular en la calidad de vida y sueño en pacientes con disfunción temporomandibular. Métodos: Se incluyeron 55 pacientes con disfunción temporomandibular que fueron desprogramados neuromuscularmente (29 mujeres y 26 hombres), con edad promedio de 34,9 ± 16,5 años. Al inicio y final de la desprogramación neuromuscular, se aplicaron las encuestas para evaluar el nivel de dolor crónico, percepción de calidad de vida relacionada con la salud oral, estrés percibido, cantidad y calidad de vida, ansiedad y depresión. Resultados: En 37 pacientes (68 por ciento) se identificó dolor a la exploración confirmado en la encuesta de dolor crónico. El puntaje de percepción de calidad de vida se correlacionó con baja calidad de sueño (r = 0,39; p = 0,008); el puntaje de dolor (r = 0,48; p = 0,003); ansiedad (r = 0,55; p = 0,003) y depresión (r = 0,41; p = 0,006). La desprogramación neuromuscular redujo los niveles de dolor referidos por el paciente de 9,9 a 2,9 (p = 0,001), el porcentaje de pacientes con pobre calidad de sueño de 60 por ciento a 29 por ciento (p < 0,0001), el puntaje de la calidad de vida de 40,7 a 23,8 (p = 0,03) y los niveles de estrés percibido de 22,1 a 19,1 (p = 0,002). Conclusiones: En pacientes con disfunción temporomandibular, la desprogramación neuromuscular reduce el nivel de dolor, se relaciona con mejor percepción en la calidad de vida, mayor calidad de sueño y disminuye el estrés percibido(AU)
Assuntos
Humanos , Qualidade de Vida , Síndrome da Disfunção da Articulação Temporomandibular/etiologia , Saúde Bucal , Qualidade do Sono , Gestão da Qualidade Total , Dor CrônicaRESUMO
La adolescencia se caracteriza por ser un periodo de desarrollo en donde se presentan cambios biológicos, fisiológicos y psicológicos que a menudo aumentan la aparición de conductas de riesgo, como el consumo de sustancias. Se han identificado algunos factores que podrían predisponer al desarrollo de esta problemática, entre los cuales están: vulnerabilidad, problemas de autonomía, presión social, eventos traumáticos, trastornos emocionales y psiquiátricos, entre otros. Los profesionales de la salud bucal pueden ayudar a prevenir y detectar casos sospechosos de uso de sustancias, cuando se observan cambios en la apariencia de los pacientes adolescentes. El propósito de este artículo es informar acerca del impacto negativo del consumo de sustancias ilícitas en la salud bucodental de los adolescentes y del reconocimiento de los signos de alerta. Además, se propone una secuencia de atención odontológica para esta población en riesgo
A adolescência caracteriza-se como um período do desenvolvimento em que ocorrem mudanças biológicas, fisiológicas e psicológicas que muitas vezes aumentam o aparecimento de comportamentos de risco, como o uso de substâncias. Foram identificados alguns fatores que podem predispor ao desenvolvimento desse problema, dentre eles: vulnerabilidade, problemas de autonomia, pressão social, eventos traumáticos, transtornos emocionais e psiquiátricos, entre outros. Profissionais de saúde bucal podem ajudar a prevenir e detectar casos suspeitos de uso de substâncias quando são observadas alterações na aparência de pacientes adolescentes. O objetivo deste artigo é relatar o impacto negativo do uso de substâncias ilícitas na saúde bucal de adolescentes e o reconhecimento de sinais de alerta. Além disso, é proposta uma sequência de atendimento odontológico para essa população de risco
Adolescence is characterized as a period of development in which biological, physiological and psychological changes occur that often increase the appearance of risk behaviors, such as substance use. Some factors have been identified that could predispose to the development of this problem: vulnerability, autonomy issues, social pressure, traumatic events, emotional and psychiatric disorders, among others. Oral health professionals can help prevent and detect suspected cases of substance use when changes in the appearance of adolescent patients are observed. The aim of this article is to inform about the negative impact of illicit substance use on the oral health of adolescents and the recognition of warning signs. In addition, a sequence of dental care is proposed for this population at risk.
Assuntos
Humanos , Masculino , Feminino , Adolescente , Saúde Bucal , Transtornos Relacionados ao Uso de Substâncias , Fatores de Risco , Assistência Odontológica , Autonomia PessoalRESUMO
Una de las consecuencias de la desprogramación neuromuscular es la rotación mandibular en sentido horario, evidenciando el punto prematuro de contacto y aumentando la dimensión vertical del paciente. En pacientes clase II con componente vertical, es un problema realizar este tipo de tratamiento, ya que por lo general este efecto de posterorrotación mandibular hace el perfil más convexo, y en algunos casos genera mordida abierta anterior, la cual se debe corregir posteriormente con el tratamiento de ortodoncia, cirugía o prótesis, lo que alarga el tiempo total de tratamiento por la necesidad de control vertical. El presente caso se trata de una mujer de 45 años de edad, dolicofacial, con tendencia a mordida abierta, mordida dual, sobremordida vertical y horizontal disminuidas, motivo de consulta dolor articular, el cual no le permite continuar con sus labores diarias, el tratamiento realizado fue desprogramación neuromuscular con un guarda oclusal inferior con el propósito de aliviar sintomatología articular y control vertical con microtornillos palatinos previo a tratamiento ortodóncico (AU)
One of the effects of the neuromuscular deprogramming treatment is the mandibular clockwise rotation, making the light premature occlusal contact more evident and increasing the patient vertical dimension. In Class II patients with vertical component is difficult to treat them due to profile worsening as an effect of the clockwise rotation creating in some patient's anterior open bite, this has to be corrected later in treatment with orthodontic intrusion, surgery or prosthodontic treatment, increasing the total time of treatment with the vertical control necessity. This case report is a 45 years old patient, dolichofacial, with anterior open bite tendency, dual bite, decreased overjet and overbite, her chief complaint was temporomandibular joint dysfunction which dont allow her to do her daily duties, the treatment for her was neuromuscular deprogramming splint for the temporomandibular joint pain, and vertical control with temporary anchorage devices (miniscrews) before the orthodontic treatment (AU)
Assuntos
Humanos , Pessoa de Meia-Idade , Dimensão Vertical , Síndrome da Disfunção da Articulação Temporomandibular/terapia , Implantes Dentários , Mordida Aberta/terapia , Rotação , Placas Oclusais , Manifestações Neuromusculares , Sobremordida/terapia , Mandíbula/fisiologia , MéxicoRESUMO
Introducción: El uso de postes de fibra de vidrio es el método actual más utilizado para la reconstrucción postendodóncica. Sin embargo, su adhesión sigue siendo impredecible debido al control limitado de su técnica de cementación. Las resinas bulk-fill revelan valores de fuerza flexural similares a la dentina y su empleo en la reconstrucción postendodóncica podría ser una alternativa viable y conservadora. Objetivo: Comparar tres técnicas de reconstrucción postendodóncica al medir su resistencia a fuerzas de desalojo, clasificar el tipo de fractura y falla adhesiva, evaluar su costo y tiempo de trabajo. Material y métodos: Se realizan 18 muestras divididas en tres grupos: grupo 1: poste más cemento de un paso, grupo 2: poste más cemento de tres pasos y grupo 3: reconstrucción postendodóncica con resina bulk-fill. Resultados: En la evaluación de la fuerza al desalojo no se encontró diferencia estadísticamente significativa en los tres grupos. Respecto al comportamiento y falla adhesiva, se encontró una diferencia significativa p < 0.001, favoreciendo a los grupos 2 y 3, por su adhesión en la porción radicular. El tipo de fractura fue restaurable para los tres grupos. Respecto al tiempo y costo, fueron significativamente menores para el grupo 3. Conclusión: En nuestro estudio no existió diferencia significativa en la fuerza al desalojo en los tres grupos; sin embargo, la hubo en el comportamiento, falla adhesiva, costo y tiempo, favoreciendo mayormente al grupo 3. La técnica de reconstrucción con resina puede ser una técnica predecible, suficientemente resistente, conservadora, rápida y de menor costo
Introduction: The use of fiberglass posts is the current method most used for post-endodontic reconstruction. However, its adhesion remains unpredictable due to the limited control of its cementing technique. Bulkfill resins reveal values of flexural strength similar to dentin and their use in post-endodontic reconstruction could be a viable and conservative alternative. Objective: Compare three post-endodontic reconstruction techniques by measuring their resistance to eviction forces, classifying the type of fracture and adhesive failure, evaluating their cost and time of work. Material and methods: 18 samples are divided into 3 groups: group 1: post plus cement of 1 step, group 2: post plus cement of 3 steps and group 3: post-endodontic reconstruction with bulk-fill resin. Results: In the evaluation of the force to the eviction, no statistically significant difference was found in the 3 groups. Regarding the behavior and adhesive failure, a significant difference was found p < 0.001, favoring groups 2 and 3, due to its adhesion in the root portion. The type of fracture was restorable for the 3 groups. Regarding time and cost, they were significantly lower for group 3. Conclusion: In our study there was no significant difference in the force to the eviction in the three groups, however there was in the behavior, adhesive failure, cost and time, favoring mainly the group 3. The technique of reconstruction with resin can be a predictable technique, Sufficiently resistant, conservative, fast and of lower cost (AU)
Assuntos
Técnica para Retentor Intrarradicular , Resinas Compostas , Restauração Dentária Permanente , Colagem Dentária , Vidro , MéxicoRESUMO
En endodoncia la tomografía cone-beam (CBCT) permite el diagnóstico y planifi cación de tratamientos. Se presenta un caso en que se detectó una desviación del conducto radicular y perforación al instalar un poste, las cuales no fueron identifi cadas en la radiografía convencional. La tomografía cone-beam facilitó el diagnóstico y la defi nición del plan de tratamiento, el cual se realizó bajo microscopio y con ultrasonido para remover los materiales de obturación previos (gutapercha y poste). Las perforaciones iatrogénicas son causa de mal pronóstico en los tratamientos endodóncicos. El cone-beam es una herramienta que permite observar tridimensionalmente los conductos radiculares, lo que facilita el diagnóstico y tratamiento a seguir (AU)
Cone-beam (CBCT) tomography is more often used in endodontics, to improve diagnosis and treatment planifi cation. In the present study we were able to detect a deviation of the root canal and perforation during the colocation of a poste, which wasn't possible with conventional radiograph. The endodontic treatment was guided with cone-beam and was executed under microscope; help out with ultrasonic tips to remove the previous obturation materials (gutta-percha and post) to also detect the original tract and to clean and desinfect the original root canal. Iatrogenic perforations cause poor prognosis of the endodontic treatments. CBCT is a tool that allows observing three-dimensional the root canals; which facilitates the diagnosis and treatment planning (AU)
Assuntos
Humanos , Masculino , Adulto , Tomografia Computadorizada de Feixe Cônico , Doença Iatrogênica , Tratamento do Canal Radicular , Raiz Dentária , Terapia por Ultrassom , Diagnóstico por Imagem , México , Microscopia , Planejamento de Assistência ao Paciente , Prognóstico , Materiais Restauradores do Canal RadicularRESUMO
Introducción: Los procedimientos de acabado y pulido de las restauraciones dentarias son fases determinantes en la práctica odontológica,ya que las superficies bien acabadas y pulidas aumentan la longevidadde la restauración, disminuyen la acumulación de placa y reducen las modificaciones del color marginal a la restauración y superficie. Objetivo: El propósito de este estudio fue evaluar tres diferentes sistemas de pulido: discos Sof-Lex, copas pulidoras Jiff y y sistema de un solopaso OptraPol, en función de la superficie obtenida en tres marcas deresinas estéticas nanohíbridas para zona anterior y posterior...
Introduction: The procedures for finishing and polishing dental restorations are crucial phases in dental practice, as well-fi nished andwell-polished surfaces increase the longevity of the restoration andreduce the buildup of plaque and marginal color changes in both therestoration and the surface. Objective: The purpose of this study wasto evaluate three diff erent polishing systems: Sof-Lex, Jiff y® polishercups, and the OptraPol one-step system, based on the surface obtainedusing three brands of cosmetic nanohybrid resins in the anterior and posterior regions...
Assuntos
Estética Dentária , Nanoestruturas , Polimento Dentário/métodos , Resinas Compostas/química , Propriedades de Superfície , Análise de Variância , Teste de Materiais , Microscopia de Força Atômica/métodos , Interpretação Estatística de DadosRESUMO
Introducción: En muchas ocasiones, el sitio edéntulo del paciente no cuenta con el sufi ciente volumen óseo para albergar un implante. El injerto óseo autólogo en bloque (IOAB) es una opción para acondicionar al individuo y poder realizar la colocación del implante. Objetivo: Determinar el porcentaje de éxito y fracaso de los IOAB y sus factores relacionados...
Introduction: Very often, there is insufficient bone volume available in the edentulous site of a patient to allow dental implant placement. One way to prepare such patients for an implant placement is to usean autologous bone block (ABB) graft. Objective: To determine the success and failure rates of ABB grafts and their associated factors...
Assuntos
Humanos , Masculino , Adulto , Feminino , Adulto Jovem , Pessoa de Meia-Idade , Implantação Dentária Endóssea/métodos , Transplante Autólogo/instrumentação , Transplante Autólogo/métodos , Transplante Ósseo/métodos , Epidemiologia Descritiva , Falha de Restauração Dentária/estatística & dados numéricos , México , Estudos Retrospectivos , Fatores de Risco , Interpretação Estatística de Dados , Resultado do TratamentoRESUMO
El tratamiento y pronóstico de las lesiones endoperiodontales depende del diagnóstico oportuno y preciso de la enfermedad endodóntica y/o periodontal. Cuando se trata de lesiones endodónticas primarias con involucración periodontal secundaria, la estrategia de tratamiento debe ser primeramente enfocada a la infección pulpar, al debridamiento y desinfección de los conductos radiculares. El objetivo de este estudio es demostrar la capacidad de reparación de una lesión endoperiodontal mediante terapia endodóntica no quirúrgica, sin posterior terapia periodontal. El caso es un paciente masculino de 10 años con necrosis pulpar del órgano dentario 46 con involucración periodontal mediante lesión en furca, la cual reparó completamente en tres meses tras el tratamiento endodóntico. Estos hallazgos se confirman radiográficamente y por la disminución de la profundidad sondeable en la zona de la lesión. Se concluye que en este tipo de casos, con involucración endodóntica primaria, la necesidad del tratamiento periodontal quirúrgico o no quirúrgico será determinada exclusivamente por la falta de reparación de la lesión por largos periodos de tiempo.
he treatment and prognosis of endo-periodontal lesions depend on the timely and accurate diagnosis of the endodontic and/or periodontal disease. In the case of primary endodontic lesions with secondary peri-odontal involvement, the treatment strategy should be focused primarily on the pulp infection and the debridement and disinfection of root canals. The aim of this study is to demonstrate the repair capacity of an endo-periodontal lesion treated with nonsurgical endodontic root therapy and no subsequent periodontal treatment. The case involves a 10-year-old male patient with pulpal necrosis and apical periodontitis of tooth 46; periodontal furcation involvement was also evident. The diagnosis was a primary endodontic lesion with secondary periodontal involvement. The furcation defect healed completely within three months of non-surgical root canal treatment, a fact confi rmed by X-rays and by the reduction in the probing depth in the area of the lesion. We conclude that in cases such as this, where there is primary endodontic involvement, surgical or non-surgical periodontal treatment should be considered exclusively if the periodontal lesion persists for long periods of time.
Assuntos
Humanos , Masculino , Criança , Defeitos da Furca/terapia , Doenças da Polpa Dentária/terapia , Doenças Periodontais/terapia , Necrose da Polpa Dentária/terapia , Tratamento do Canal Radicular/métodos , Cicatrização/fisiologia , Faculdades de Odontologia , Seguimentos , México , Dente Molar/lesões , Dente Molar , Resultado do TratamentoRESUMO
BACKGROUND: Pulse oximetry has been suggested as a screening test for congenital heart disease (CHD) in asymptomatic newborns. However, most newborns in Mexico are discharged from the hospital without this evaluation. OBJECTIVE: To evaluate pulse oximetry as a screening test for critical congenital heart disease (CCHD) in term newborns. METHODS: We conducted a cross-sectional study in term newborns between July 2010 and April 2011. Pulse oximetry was determined before hospital discharge; in case of post-ductal oxygen saturation < 95%, a Doppler echocardiogram was performed. RESULTS: From 1,037 newborns screened, two had CCHD, one had pulmonary atresia and ventricular septal defect, and one Ebstein´s anomaly. Minor CHD was present in 10 babies. The overall prevalence of CHD was 11.5 per 1000 live births, and the prevalence of CCHD was 3.9 per 1000 live births. For those with critical disease, pulse oximetry had a sensitivity of 100%, specificity 98.8%, positive predictive value 14.2%, negative predictive value 100%, and positive likelihood ratio of 86.2. In regression analysis, oxygen saturation, respiratory frequency, and postnatal age were related with CCHD. CONCLUSIONS: Pulse oximetry had a good sensitivity and specificity for the identification of critical congenital heart disease in term newborns. Low oxygen saturation, higher respiratory frequency, and early postnatal age were related with congenital heart disease.
Assuntos
Cardiopatias Congênitas/diagnóstico , Triagem Neonatal/métodos , Oximetria/métodos , Estudos Transversais , Feminino , Cardiopatias Congênitas/epidemiologia , Cardiopatias Congênitas/fisiopatologia , Humanos , Recém-Nascido , Masculino , México/epidemiologia , Valor Preditivo dos Testes , Prevalência , Análise de Regressão , Sensibilidade e EspecificidadeRESUMO
Aim of the Study. To compare the effect of glossopharyngeal nerve block with topical anesthesia on the tolerance of patients to upper gastrointestinal endoscopy. Methods. We performed a clinical trial in one hundred patients undergoing upper gastrointestinal endoscopy. Subjects were randomly assigned to one of the following two groups: (1) treatment with bilateral glossopharyngeal nerve block (GFNB) and intravenous midazolam or (2) treatment with topical anesthetic (TASS) and intravenous midazolam. We evaluated sedation, tolerance to the procedure, hemodynamic stability, and adverse symptoms. Results. We studied 46 men and 54 women, from 17 to 78 years of age. The procedure was reported without discomfort in 48 patients (88%) in the GFNB group and 32 (64%) in the TAAS group; 6 patients (12%) in GFNB group and 18 (36%) in TAAS group reported the procedure as little discomfort (χ (2) = 3.95, P = 0.04). There was no difference in frequency of nausea (4% in both groups) and retching, 4% versus 8% for GFNB and TASS group, respectively (P = 0.55). Conclusions. The use of glossopharyngeal nerve block provides greater comfort and tolerance to the patient undergoing upper gastrointestinal endoscopy. It also reduces the need for sedation.
RESUMO
BACKGROUND: Recent studies have reported an increase in the prevalence of obesity and metabolic syndrome in children and adolescents. However, few have focused how diabetes mellitus and metabolic syndrome together in parents can influence on obesity and metabolic disturbances in offspring. OBJECTIVE: To know the risk obesity and metabolic disturbance in children, adolescents, and young adults whose parents have diabetes mellitus and metabolic syndrome. METHODS: A comparative survey was made in healthy children of parents with diabetes mellitus and metabolic syndrome compared with offspring of healthy parents. We performed anthropometry and evaluated blood pressure, glucose, total cholesterol, HDL cholesterol, and triglycerides levels in plasma. We registered parent antecedents to diabetes mellitus and metabolic syndrome and investigated the prevalence of overweight, obesity, and metabolic disturbances in offspring. RESULTS: We studied 259 subjects of 7 to 20 years of age. The prevalence of overweight and obesity was 27% and 37%, respectively. The highest proportion of BMI >95th of the entire group was found in offspring with both diabetic parents. Glucose and total cholesterol levels were lower in the group with healthy parents compared with the group with diabetic mother and metabolic syndrome but with healthy father. HDL cholesterol was higher in the group with both healthy parents than in the group with diabetic mother and metabolic syndrome but healthy father. CONCLUSIONS: The offspring of parents with diabetes plus metabolic syndrome showed higher proportion of variables related to metabolic syndrome compared with healthy parents.
Assuntos
Diabetes Mellitus/genética , Pai , Síndrome Metabólica/genética , Mães , Obesidade/genética , Adolescente , Análise de Variância , Biomarcadores/sangue , Glicemia/análise , Pressão Sanguínea/genética , Índice de Massa Corporal , Estudos de Casos e Controles , Distribuição de Qui-Quadrado , Criança , Colesterol/sangue , HDL-Colesterol/sangue , Diabetes Mellitus/sangue , Diabetes Mellitus/epidemiologia , Diabetes Mellitus/fisiopatologia , Feminino , Predisposição Genética para Doença , Humanos , Masculino , Síndrome Metabólica/sangue , Síndrome Metabólica/epidemiologia , Síndrome Metabólica/fisiopatologia , México/epidemiologia , Obesidade/sangue , Obesidade/epidemiologia , Obesidade/fisiopatologia , Linhagem , Fenótipo , Prevalência , Medição de Risco , Fatores de Risco , Fatores de Tempo , Triglicerídeos/sangue , Adulto JovemRESUMO
OBJECTIVE: Intensified management of gestational diabetes mellitus can normalize birth weight. However, it is still unknown whether intrauterine exposure to maternal diabetes is a risk factor for changing hormone levels involved in the development of insulin resistance in these infants. We compared insulin and leptin levels in appropriate for gestational age (AGA) infants of diabetic and non diabetic mothers. METHODS: We performed a cross-sectional study in the department of Neonatology of the Hospital of Gynecology-Pediatrics, in Leon, Mexico. We evaluated 182 full term AGA newborns (86 infants of diabetic and 96 of non-diabetic mothers). A venous blood sample was taken from cord blood immediately after the separation of the placenta and glucose, insulin and leptin levels were measured. In all diabetic mothers HbA1c was also evaluated immediately post-partum. FINDINGS: Leptin, insulin and insulin resistance index were significantly higher in infants of diabetic mothers. Leptin levels were positive correlated with insulin, parents' body mass index and age in the entire group. In infants of diabetic mothers only insulin levels showed a significantly correlation, whereas in those of non-diabetic mothers only mothers' age was significantly correlated with leptin levels. CONCLUSION: AGA infants of diabetic mothers showed higher leptin, insulin levels and insulin resistance index than those of non-diabetic mothers.
RESUMO
BACKGROUND: Iron overload can affect cardiac structure and function by the production of free radicals in addition to iron deposits in heart muscle. The purpose of this study was to compare traditional and non-traditional cardiovascular risk factors (CVRF) in children and adolescents on renal replacement with and without iron overload. Also, we evaluated the relationships between iron overload and left ventricular mass (LVM). METHODS: First, in a cross-sectional study, we evaluated traditional and non-traditional CVRF in 143 children and adolescents, 48 on peritoneal dialysis (PD), 53 on hemodialysis (HD) and 42 after renal transplantation according to iron overload. In a second phase with a case-control study, we measured LVM in 12 case patients and 12 matched controls. RESULTS: Iron overload was identified in 15 patients (10.5%), 11 in HD and 4 in PD (P = 0.002). The group with iron overload had lower body mass index (17 versus 19; P = 0.01), total cholesterol (132 versus 165 mg/dL; P = 0.03) and hemoglobin (8.5 versus 10.6 g/dL; P = 0.003) but higher interleukin (IL)-6 levels (4.8 versus 3.6 ng/L; P = 0.04) and hypertension diagnosis (79 versus 48%; P < 0.001) than those without iron overload. Ferritin showed a positive correlation with C-reactive protein (CRP) and IL-6 levels. In a subgroup of 24 patients (12 with and 12 without iron overload), LVM was not different. However, ferritin levels showed a borderline positive correlation (r = 0.44, P = 0.05) with LVM. CONCLUSION: Children and adolescents with iron overload show more CVRFs, especially if they received replacement therapy with HD. Ferritin is related to CRP and IL-6 levels.
Assuntos
Doenças Cardiovasculares/etiologia , Sobrecarga de Ferro/etiologia , Falência Renal Crônica/complicações , Transplante de Rim , Diálise Renal/efeitos adversos , Adolescente , Proteína C-Reativa/metabolismo , Estudos de Casos e Controles , Criança , Pré-Escolar , Estudos Transversais , Feminino , Ferritinas/sangue , Humanos , Interleucina-6/sangue , Falência Renal Crônica/terapia , Masculino , Prognóstico , Fatores de RiscoRESUMO
BACKGROUND: Adhesion molecules in sepsis syndrome are correlated with the severity of illness and may be considered as predictors of survival outcome in adults. However, only few studies have been performed in infants and none using international criteria for sepsis. OBJECTIVE: To determine whether adhesion molecules during the first 7 days of the disease could predict sepsis outcome and its severity. MATERIAL AND METHODS: We performed a prospective study in 88 infants with sepsis and 30 controls. Soluble intercellular adhesion molecule (ICAM)-1, vascular cell adhesion molecule (VCAM)-1, and E-selectin levels were determined at days 1, 3 and 7 of follow-up in those patients with sepsis and only one determination in the control group. The main outcome measure was mortality during 10 days of monitoring. RESULTS: Positive hemoculture was reported in 64(72.7%). ICAM-1, VCAM-1, and E-selectin levels were higher in the group of sepsis than in the control group. However, no association was found between ICAM-1, VCAM-1 or E-selectin levels with sepsis severity. Mortality linked to sepsis was observed in 9 patients (10.2%). In the logistic regression analysis, those variables positively associated with mortality were the increase in ICAM-1 levels > 250 ng/mL between day 1 to 3, number of amines and the baseline severity of sepsis. However, we did not identify in those patients who died a specific pattern in adhesion molecules levels during follow up. CONCLUSIONS: ICAM-1 levels, number of amines and severity of sepsis levels predict mortality during 10 days of monitoring in infants younger than 1 year of age with sepsis.
Assuntos
Selectina E/sangue , Mortalidade Hospitalar , Molécula 1 de Adesão Intercelular/sangue , Sepse/sangue , Molécula 1 de Adesão de Célula Vascular/sangue , Bacteriemia/sangue , Bacteriemia/mortalidade , Biomarcadores , Ensaio de Imunoadsorção Enzimática , Feminino , Hospitais Gerais/estatística & dados numéricos , Humanos , Lactente , Unidades de Terapia Intensiva Pediátrica/estatística & dados numéricos , Modelos Logísticos , Masculino , México/epidemiologia , Insuficiência de Múltiplos Órgãos/sangue , Insuficiência de Múltiplos Órgãos/mortalidade , Estudos Prospectivos , Sepse/mortalidade , Choque Séptico/sangue , Choque Séptico/mortalidade , Resultado do TratamentoRESUMO
The authorities of the High Medical Specialized Units (HMSUs) Obstetric/Gynecology Service (OB/GYN) and Intensive Care Unit (ICU) elaborated a strategy, which included the organization and interrelation of both hospital services and the implementation of an Epidemiologic Monitoring Program for all critical complicated pregnancies. This plan consisted in an assignment of personnel for special care, immediate communication with heads of services to coordinate the attention and to facilitate the resources for medical attention in these patients, as well as daily follow up by the authorities until complete resolution. Through epidemiological monitoring, 274 cases of pregnant women with high risk of mortality were identified during 2005, and 437 during 2006 (increased 59 %). The admittance to ICU for this reason in 2003 was 17; in 2005 was 24 and in 2006 was 42 (147 % from 2003 to 2006). Maternal deaths diminished from: 3/17 (17.6 %) to 1/24 (4.1 %) to 2/42 (4.7 %) during the same years, respectively. The maternal death rate from 2004 to 2006 was: 33.2, 17.4, and 22 per 100,000 newborns, respectively, below the national and institutional average. The coordination between the Headquarters and the HMSUs that take care of obstetrical patients helped diminution maternal death over this period.
Assuntos
Mortalidade Materna , Complicações na Gravidez/mortalidade , Complicações na Gravidez/prevenção & controle , Feminino , Humanos , Vigilância da População , Gravidez , Cuidado Pré-NatalRESUMO
OBJECTIVE: To estimate autonomic balance and pulmonary function in obese women according to their baseline weight and weight gain during pregnancy. DESIGN: A cohort study. SETTING: Hospital of Gynecology and Obstetrics in Leon, Mexico. POPULATION: One hundred and seventy-eight healthy pregnant women (88 obese and 90 non-obese). METHODS: At first visit of pregnancy and in the third trimester blood pressure, anthropometric measurements, glucose, insulin, and leptin levels were evaluated and spirometry, oximetry, and 60 minutes electrocardiograph monitoring were performed. MAIN OUTCOME MEASURES: Heart rate variability and pulmonary function. RESULTS: Blood pressure levels, glucose, insulin, and leptin levels were higher in obese women, whereas total power of heart rate variability was lower in this group than in non-obese women at the beginning of pregnancy. In the third trimester, the standard deviation of all the normal R-R intervals was lower in obese women, whereas blood pressure and glucose levels remain higher. In the multiple regression analysis, the change in forced expiratory volume at 1 second/forced vital capacity (FEV1/FVC) ratio and leptin levels independently of weight gain were associated to low-frequency/high-frequency (LF/HF) index at third trimester (R2=0.21; p<0.001 for the model) only in obese women. CONCLUSIONS: LF/HF index at third trimester of pregnancy is associated with increase in leptin levels and decrease in FEV1/FVC in obese women independently of weight gain.
Assuntos
Volume Expiratório Forçado , Frequência Cardíaca/fisiologia , Leptina/sangue , Obesidade/fisiopatologia , Complicações na Gravidez/fisiopatologia , Capacidade Vital , Glicemia/análise , Pressão Sanguínea , Estudos de Coortes , Feminino , Humanos , Pulmão/fisiologia , Obesidade/sangue , Gravidez/sangue , Gravidez/fisiologia , Complicações na Gravidez/sangue , Análise de RegressãoRESUMO
BACKGROUND: The Holt-Oram syndrome (HOS) is characterized by skeletal abnormalities, frequently accompanied by congenital cardiac defects. It was first described by Holt and Oram in 1960. It has a prevalence of 0.95/10,000 live newborns. The syndrome shows a dominant autosomic heritance with high penetrance. A mutation in the transcription gene factor TBX5 has been identified. This factor has been shown to be important in the heart and upper extremities development. CLINICAL CASE: A 17 year-old boy with muscle-skeletal abnormalities in forearms and hands, with implantation defects of thumbs and narrow shoulders as well as wide atrial septal defect type osteum secundum. He also showed portal cavernomatosus degeneration which conditioned portal extrahepatic hypertension and esophageal varicose veins. The diagnosis was established by clinical, radiological and auxiliary studies. His parents were also studied, and they did not show abnormalities. CONCLUSIONS: Two previous cases have been reported in the Mexican medical literature, both due to de novo genetic mutation. However, none has been associated with portal cavernomatosus degeneration and portal hypertension.