RESUMO
OBJECTIVE: This work investigates the relationship between early body composition changes and neurodevelopment at 1 year age corrected for prematurity (CA). STUDY DESIGN: A prospective, longitudinal study to measure body composition weekly in 34 very low birth weight preterm infants using air displacement plethysmography, beginning when infants stabilized after birth until discharge. Neurodevelopmental testing (Bayley Scales of Infant Development-III) was performed at 12 months CA. Linear mixed effects models were used to obtain inpatient subject-specific changes in fat-free mass (FFM) and fat mass (FM), which were then used as predictors of Bayley subscale scores in subsequent linear regression models, adjusting for potential confounders. Protein and energy provision were calculated for the first week of life. RESULTS: Greater FFM gains while inpatient were associated with improved cognitive and motor scores at 12 months CA (P = .002 for both). These relationships remained significant when adjusting for birth weight, gestational age, and intraventricular hemorrhage (P ≤ .05 for both). Similar analysis was performed for FM gains without significant findings. Increased provision of protein and calories during the first week of life was positively associated with FFM gains (P ≤ .01 for both), but not FM gains (P ≥ .2 for both), throughout hospitalization. CONCLUSIONS: Increased FFM gains, but not FM gains, during hospitalization are associated with improved neurodevelopment at 12 months CA. As early FM gains may be associated with long-term risk, more research is needed to develop strategies that optimize FFM gains while minimizing FM gains in very low birth weight preterm infants.
Assuntos
Composição Corporal , Cognição , Recém-Nascido Prematuro/crescimento & desenvolvimento , Recém-Nascido de muito Baixo Peso , Desempenho Psicomotor , Feminino , Humanos , Lactente , Recém-Nascido , Modelos Lineares , Estudos Longitudinais , Masculino , Pletismografia de Impedância , Estudos ProspectivosRESUMO
OBJECTIVE: To investigate the relationship between maternal prepregnancy body mass index and early infant growth and body composition. STUDY DESIGN: Prospective cohort study performed at a university hospital/surrounding community. Ninety-seven nondiabetic mothers with singleton, term, healthy infants completed study visits at 2 weeks and 3 months of age. Before pregnancy, 59 mothers were normal weight, 18 were overweight, and 20 were obese. Infant anthropometrics and body composition via air-displacement plethysmography were measured. Infant feeding information and maternal prepregnancy weight were self-reported. Additional data were obtained via self-report and the medical record. Main outcome measures were change in weight, length, fat-free mass, and fat mass from 2 weeks to 3 months of age. Analysis was done via multivariate linear regression. RESULTS: At 2 weeks, anthropometrics and body composition did not differ across maternal body mass index groups. At 3 months, infants of overweight or obese mothers had gained less weight (P = .02), grew less in length (P = .01), and gained less fat mass (P = .01). Adjustment for breastfeeding status and regression to the mean via conditional change variables did not alter the results. The results were not altered after adjusting for maternal glucose values from a 50-g glucose challenge and for maternal smoking in a subset including 80% of the women. CONCLUSIONS: Maternal overweight/obesity is associated with early deceleration in linear growth and adipose tissue accrual; replication of these findings is needed.
Assuntos
Adiposidade , Estatura , Desenvolvimento Infantil , Obesidade , Complicações na Gravidez , Aumento de Peso , Adulto , Índice de Massa Corporal , Aleitamento Materno , Estudos de Coortes , Feminino , Humanos , Lactente , Modelos Lineares , Masculino , Análise Multivariada , Sobrepeso , Pletismografia , Gravidez , Estudos Prospectivos , AutorrelatoRESUMO
Projections for the year 2030 show that Latinos are expected to make the largest population increase. Cultural values create expectation levels about what will happen to the elderly. Acculturation is a concept that has been studied extensively, yet the relationship between age and acculturation has not been a focus of study. The present study has proposed an alternate way of scoring the ARSMA-II based on receiver operating characteristics. Specifically, this approach looks at participants' responses to two individual items to determine the level of acculturation of the older adults. It is a quicker method and one that could save healthcare providers a great deal of time as well as help them better understand their clients' level of acculturation; thus, being able to provide the appropriate educational materials.