RESUMO

The outcomes of mild hyperphenylalaninemia (MHP) in three children of two sisters were compared. The IQ of the child from an untreated pregnancy was 105; the developmental quotients of the two infant offspring from treated and untreated pregnancies were 122 and 114, respectively. The IQ of the sister with untreated MHP was 101; that of the sister who received dietary treatment for MHP during infancy was 90. Thus MHP and maternal MHP appear to have been clinically inconsequential in this family.

Assuntos

Inteligência , Fenilalanina/sangue , Complicações na Gravidez , Adulto , Desenvolvimento Infantil , Diabetes Gestacional/sangue , Diabetes Gestacional/tratamento farmacológico , Feminino , Genótipo , Humanos , Lactente , Recém-Nascido , Inteligência/genética , Masculino , Fenilalanina/genética , Fenilcetonúrias/sangue , Fenilcetonúrias/dietoterapia , Fenilcetonúrias/genética , Gravidez