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1.
Rev. gastroenterol. Peru ; 42(3)jul. 2022.
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1423942

RESUMO

El bezoar gástrico es una tumoración por cuerpo extraño que resulta de la acumulación de material no digerible en el estómago. El tricobezoar es uno de ellos y frecuentemente se presenta en la población femenina joven que padece trastornos psiquiátricos. La presentación del bezoar gástrico es insidiosa e inespecífica, teniendo un curso inicialmente asintomático por años, hasta que alcanza un tamaño que evidencia síntomas. El método diagnóstico de elección es la endoscopía, ya que permite visualizar el bezoar y plantear el tratamiento. El abordaje terapéutico estará determinado por el tipo, tamaño y consistencia de este; sin embargo, la resolución quirúrgica es la de elección, la cual siempre debe estar asociada a tratamiento psiquiátrico para prevenir la recurrencia del cuadro. Se presenta el caso de una paciente de 19 años con el diagnóstico de tricobezoar gástrico, asociado a tricotilomanía y tricofagia como patologías de fondo, y se realiza una revisión de la literatura.


A gastric bezoar is a foreign body tumor that results from the accumulation of indigestible material in the stomach. The trichobezoar is one of them and frequently occurs in the young female population suffering from psychiatric disorders. The presentation of the gastric bezoar is insidious and nonspecific, having an initially asymptomatic course for years, until it reaches a size that shows symptoms. The diagnostic method of choice is endoscopy since it allows the bezoar to be visualized and propose the treatment. The therapeutic approach will be determined by its type, size, and consistency; however, surgical resolution is the one of choice, which must always be associated with psychiatric treatment to prevent recurrence of the condition. The case of a 19-year-old patient with a diagnosis of gastric trichobezoar, associated with trichotillomania and trichophagia as underlying pathologies is presented, and a literature review is carried out.

2.
Rev Gastroenterol Peru ; 42(3): 193-198, 2022.
Artigo em Espanhol | MEDLINE | ID: mdl-36746501

RESUMO

A gastric bezoar is a foreign body tumor that results from the accumulation of indigestible material in the stomach. The trichobezoar is one of them and frequently occurs in the young female population suffering from psychiatric disorders. The presentation of the gastric bezoar is insidious and nonspecific, having an initially asymptomatic course for years, until it reaches a size that shows symptoms. The diagnostic method of choice is endoscopy since it allows the bezoar to be visualized and propose the treatment. The therapeutic approach will be determined by its type, size, and consistency; however, surgical resolution is the one of choice, which must always be associated with psychiatric treatment to prevent recurrence of the condition. The case of a 19-year-old patient with a diagnosis of gastric trichobezoar, associated with trichotillomania and trichophagia as underlying pathologies is presented, and a literature review is carried out.


Assuntos
Bezoares , Tricotilomania , Feminino , Humanos , Adulto Jovem , Adulto , Bezoares/diagnóstico , Bezoares/diagnóstico por imagem , Estômago/cirurgia , Tricotilomania/complicações , Tricotilomania/diagnóstico , Tricotilomania/terapia , Endoscopia/efeitos adversos
4.
Neuropharmacology ; 117: 249-259, 2017 05 01.
Artigo em Inglês | MEDLINE | ID: mdl-28232061

RESUMO

Here we provide evidence that repeated immobilization stress (RIS) in rats induces a persistent increase in noradrenergic activity in the anterior aspects of the anterolateral bed nucleus of the stria terminalis (alBNST). This increase in noradrenergic activity results from both enhanced synthesis and reuptake of norepinephrine (NE). It leads to a decrease in the synaptic availability of NE, which elicits an augmented noradrenergic response to the inhibitors of NE reuptake (NRIs), such as desipramine (DMI), an antidepressant. The enduring depression-like behavior and the augmentation of the climbing behavior seen in repeatedly stressed rats following subchronic administration of DMI in the forced swimming test (FST) might be explained by a dysregulation of noradrenergic transmission observed in alBNST. Taken together, we propose that dysregulation of noradrenergic transmission such as the one described in the present work may represent a mechanism underlying major depressive disorders (MDD) with melancholic features in humans.


Assuntos
Antidepressivos Tricíclicos/farmacologia , Transtorno Depressivo/tratamento farmacológico , Desipramina/farmacologia , Norepinefrina/metabolismo , Restrição Física/psicologia , Núcleos Septais/efeitos dos fármacos , Anfetamina/farmacologia , Animais , Ansiedade/tratamento farmacológico , Ansiedade/metabolismo , Estimulantes do Sistema Nervoso Central/farmacologia , Transtorno Depressivo/metabolismo , Modelos Animais de Doenças , Espaço Extracelular/efeitos dos fármacos , Espaço Extracelular/metabolismo , Masculino , Atividade Motora/efeitos dos fármacos , Atividade Motora/fisiologia , Distribuição Aleatória , Ratos Sprague-Dawley , Núcleos Septais/metabolismo , Estresse Psicológico/tratamento farmacológico , Estresse Psicológico/metabolismo , Transmissão Sináptica/efeitos dos fármacos , Transmissão Sináptica/fisiologia
5.
Biomedica ; 36(2): 220-9, 2016 Jun 03.
Artigo em Inglês | MEDLINE | ID: mdl-27622483

RESUMO

INTRODUCTION: Despite the reduction of poverty in Perú, the prevalence of anemia in the country remains high.  OBJECTIVE: To identify socio-demographic, child and maternal-child care factors associated with anemia in children between 6 and 35 months in Perú.  MATERIALS AND METHODS: We conducted an analytical and descriptive study that included registered data from the national survey on demography and family health, 2007-2013, on children between 6 and 35 months old, including the measurement of blood hemoglobin. Anemia was confirmed by hemoglobin-altitude corrected values below 11 mg/dl. We used multivariate logistic regression models to assess potential associated factors for anemia.  RESULTS: Anemia prevalence was high (47.9%). Twelve factors were independently associated with anemia in children: Socio-demographic factors such as living outside Lima and Callao, in a low socioeconomic household, and having an adolescent mother with low education level; child-related factors as being male, younger than 24 months of age, and having fever in the previous two weeks, and maternal-child care factors such as lack of prenatal control in the first trimester of pregnancy, lack or short period of iron supplementation during pregnancy, house delivery, anemia detection at the moment of the survey, and lack of intestinal anti-parasite preventive treatment in the child.  CONCLUSIONS: The analysis of survey data provided valuable information about factors associated with anemia in children between 6 and 35 months, which can be used to increase the coverage and effectiveness of maternal-child care practices.


Assuntos
Anemia/epidemiologia , Hemoglobinas/química , Criança , Humanos , Mães , Peru , Pobreza , Prevalência
6.
Vaccine ; 34(39): 4738-4743, 2016 09 07.
Artigo em Inglês | MEDLINE | ID: mdl-27521230

RESUMO

Streptococcus pneumoniae is the leading cause of bacterial pneumonia, meningitis and sepsis in children worldwide. Despite available evidence on pneumococcal conjugate vaccine (PCV) impact on pneumonia hospitalizations in children, studies demonstrating PCV impact in morbidity and mortality in middle-income countries are still scarce. Given the disease burden, PCV7 was introduced in Peru in 2009, and then switched to PCV10 in late 2011. National public healthcare system provides care for 60% of the population, and national hospitalization, outpatient and mortality data are available. We thus aimed to assess the effects of routine PCV vaccination on pneumonia hospitalization and mortality, and acute otitis media (AOM) and all cause pneumonia outpatient visits in children under one year of age in Peru. We conducted a segmented time-series analysis using outcome-specific regression models. Study period was from January 2006 to December 2012. Data sources included the National information systems for hospitalization, mortality, outpatient visits, and RENACE, the national database of aggregated weekly notifications of pneumonia and other acute respiratory diseases (both hospitalized and non-hospitalized). Study outcomes included community acquired pneumonia outpatient visits, hospitalizations and deaths (ICD10 codes J12-J18); and AOM outpatient visits (H65-H67). Monthly age- and sex-specific admission, outpatient visit, and mortality rates per 100,000 children aged <1year, as well as weekly rates for pneumonia and AOM recorded in RENACE were estimated. After PCV introduction, we observed significant vaccine impact in morbidity and mortality in children aged <1year. Vaccine effectiveness was 26.2% (95% CI 16.9-34.4) for AOM visits, 35% (95% CI 8.6-53.8) for mortality due to pneumonia, and 20.6% (95% CI 10.6-29.5) for weekly cases of pneumonia hospitalization and outpatient visits notified to RENACE. We used secondary data sources which are usually developed for other non-epidemiologic purposes. Despite some data limitations, our results clearly demonstrate the overall benefit of PCV vaccination in Peru.


Assuntos
Vacina Pneumocócica Conjugada Heptavalente/uso terapêutico , Infecções Pneumocócicas/prevenção & controle , Vacinas Pneumocócicas/uso terapêutico , Pneumonia/prevenção & controle , Vacina Pneumocócica Conjugada Heptavalente/administração & dosagem , Hospitalização/estatística & dados numéricos , Humanos , Programas de Imunização , Lactente , Análise de Séries Temporais Interrompida , Morbidade , Otite Média/epidemiologia , Otite Média/prevenção & controle , Peru/epidemiologia , Infecções Pneumocócicas/mortalidade , Vacinas Pneumocócicas/administração & dosagem , Pneumonia/mortalidade
7.
Biomédica (Bogotá) ; Biomédica (Bogotá);36(2): 220-229, jun. 2016. tab
Artigo em Espanhol | LILACS | ID: lil-791111

RESUMO

Introducción. A pesar de la disminución de la pobreza en Perú, la prevalencia de la anemia infantil en el país continúa siendo alta. Objetivo. Determinar los factores sociodemográficos y las características del cuidado materno-infantil asociadas con la anemia en niños de seis a 35 meses de edad en Perú. Materiales y métodos. Se hizo un estudio observacional que incluyó los datos sobre hemoglobina sanguínea registrados en la Encuesta Demográfica y de Salud Familiar (ENDES), 2007-2013, en niños entre los seis y los 35 meses de edad. Mediante un análisis multivariado de regresión logística, se identificaron los factores asociados con la anemia, definida como una hemoglobina corregida por altitud, menor de 11 mg/dl. Resultados. La prevalencia de anemia fue alta (47,9 %). Se identificaron doce factores asociados con la anemia: factores sociodemográficos como vivir fuera de Lima y Callao; en un hogar con bajo nivel socioeconómico; tener una madre adolescente y con bajo nivel educativo; ser de sexo masculino con edad menor de 24 meses y antecedentes de fiebre reciente, y factores relacionados con el cuidado materno-infantil como la falta de control prenatal en el primer trimestre, la falta de suplemento de hierro durante el embarazo o administrado durante un periodo breve, parto en el domicilio, diagnóstico de anemia en la madre en el momento de la encuesta y ausencia de tratamiento antiparasitario preventivo en el niño. Conclusiones. La ENDES proporcionó información valiosa sobre los factores asociados con la anemia en niños de seis a 35 meses, cuyo conocimiento debe mejorar la cobertura y la efectividad de prácticas adecuadas de cuidado materno-infantil.


Introduction: Despite the reduction of poverty in Perú, the prevalence of anemia in the country remains high. Objective: To identify socio-demographic, child and maternal-child care factors associated with anemia in children between 6 and 35 months in Perú. Materials and methods: We conducted an analytical and descriptive study that included registered data from the national survey on demography and family health, 2007-2013, on children between 6 and 35 months old, including the measurement of blood hemoglobin. Anemia was confirmed by hemoglobin-altitude corrected values below 11 mg/dl. We used multivariate logistic regression models to assess potential associated factors for anemia. Results: Anemia prevalence was high (47.9%). Twelve factors were independently associated with anemia in children: Socio-demographic factors such as living outside Lima and Callao, in a low socioeconomic household, and having an adolescent mother with low education level; child-related factors as being male, younger than 24 months of age, and having fever in the previous two weeks, and maternal-child care factors such as lack of prenatal control in the first trimester of pregnancy, lack or short period of iron supplementation during pregnancy, house delivery, anemia detection at the moment of the survey, and lack of intestinal anti-parasite preventive treatment in the child. Conclusions: The analysis of survey data provided valuable information about factors associated with anemia in children between 6 and 35 months, which can be used to increase the coverage and effectiveness of maternal-child care practices.


Assuntos
Anemia/prevenção & controle , Saúde da Criança , Cuidado da Criança , Ciências da Nutrição Infantil , Bem-Estar Materno
8.
Rev. neuro-psiquiatr. (Impr.) ; 77(2): 86-94, abr. 2014. tab
Artigo em Espanhol | LILACS-Express | LILACS, LIPECS | ID: lil-722540

RESUMO

Objetivos: Explorar los factores asociados a mortalidad en pacientes con infarto cerebral que fueron hospitalizados en el Instituto Nacional de Ciencias Neurológicas. Material y Métodos: Se revisaron las historias clínicas de pacientes con diagnóstico de infarto cerebral hospitalizados en el Instituto Nacional de Ciencias Neurológicas, durante Enero del 2008 hasta Diciembre del 2009. Se describen las variables demográficas y clínicas de los pacientes, además se utilizó el modelo de regresión logística para explorar los factores asociados a mortalidad en los pacientes. Resultados: Se analizaron 461 historias clínicas de pacientes con infarto cerebral. El promedio de edad fue de 67 años, el 56% fueron hombres. La mortalidad fue del 7,6%, IC 95% (5,3-10,4); los factores asociados a mortalidad que tuvieron significancia estadística fueron: el déficit sensitivo OR=2,7, cefalea OR=2,75, trastorno de conciencia OR=12, escala NIHSS al ingreso OR=1,25 y el territorio vascular anterior OR=2,65. Conclusiones: en éste estudio exploratorio los factores asociados a mortalidad intrahospitalaria por infarto cerebral fueron la presencia de déficit sensitivo, cefalea, pérdida de conciencia, déficit neurológico severo y territorio vascular de la circulación anterior.


Objectives: To explore associated factors to mortality of patients with cerebral infarction. Methods: We reviewed clinical records of patients with diagnosis of cerebral infarction hospitalized at the Instituto Nacional de Ciencias Neurologicas, January 2008 to December 2010. We describe the demographic and clinical variables. In addition, the logistic regression model was used to determine the factors associated with mortality in these patients. Results: We reviewed clinical records of 461 patients with brain infarction. The median age was 67 years and 56% were men. We calculated a ratio of 7.6% dead, 95% IC (5.3-10.4); the factors significantly associated are the sensitive deficit OR = 2.7, headache OR = 2.75, consciousness disorder OR = 12, NIHSS scale OR = 1.25 and anterior vascular territory OR = 2.65. Conclusions: in this exploratory study factors associated with mortality by cerebral infarction were the presence of sensitive deficit, headache, loss of consciousness, severe neurological deficit and vascular territory of the anterior circulation.

9.
Rev. colomb. gastroenterol ; 29(1): 69-73, ene.-mar. 2014. ilus
Artigo em Espanhol | LILACS | ID: lil-712511

RESUMO

Se reporta dos casos de pancreatitis secundaria a la infección por citomegalovirus confirmado por reacción en cadena de la polimerasa en tiempo real (PCR-RT) en pacientes portadores del virus de la inmunodeficiencia humana (VIH). Se descartaron otras causas mediante exámenes auxiliares. Ambos pacientes fueron tratados con ganciclovir y se obtuvo una mejoría tanto clínica como en los exámenes auxiliares. Esta patología no debe pasar desapercibida en pacientes VIH positivos a pesar de no presentar la característica clínica de pancreatitis aguda.


Assuntos
Humanos , Masculino , Adulto , Feminino , Adulto Jovem , Citomegalovirus , Síndromes de Imunodeficiência , Pancreatite
10.
Rev. peru. med. exp. salud publica ; 30(4): 595-600, oct.-dic. 2013. ilus, graf, tab
Artigo em Espanhol | LILACS, LIPECS | ID: lil-698118

RESUMO

Objetivos. Determinar el daño genotóxico en trabajadores de una minería artesanal expuestos a mercurio. Materiales y métodos. Estudio observacional de corte transversal, en el cual se evaluaron trabajadores expuestos a mercurio (n=83), de quienes se colectaron células por hisopado bucal para su posterior tinción, revisión microscópica y recuento de micronúcleos y otras alteraciones nucleares. También se colectó orina de 24 h para la determinación de mercurio inorgánico. Resultados. El 68,7% de las personas estudiadas fueron de sexo masculino, la media de edad fue de 43 ± 12,4 años (rango: 16-76). El tiempo promedio de exposición ocupacional a mercurio fue de 12,1 ± 6,7 años, y el contacto con mercurio fue de 4,1 ± 3,6 kg por persona por día. El 93% de los evaluados no utilizaban equipos de protección personal durante la manipulación del mercurio. Los resultados del monitoreo biológico evidenciaron que el 17% de los evaluados presentaron concentraciones de mercurio en orina mayor a los 2,5 µg/L; siendo este valor el límite de detección de la técnica de medición utilizada. Los resultados de la evaluación genotóxica evidenciaron que el 15% de las personas con exposición laboral a mercurio presentaron micronúcleos en células de epitelio bucal; hallándose otros indicadores de alteración nuclear como los puentes nucleoplásmicos, gemaciones y binucleaciones, que también son considerados como eventos genotóxicos asociados a la exposición por agentes de riesgo físico o químico. Conclusiones. El hallazgo de micronúcleos en células del epitelio bucal reflejan daño genotóxico asociado a la exposición laboral por mercurio utilizado en las actividades de minería artesanal.


Objectives. To determine the genotoxic damage among artisanal and small-scale mining workers exposed to mercury. Materials and methods. Observational cross-sectional study which evaluated mercury-exposed workers (n=83), whose cells were collected by mouth swab for further staining, microscopic observance, micronuclei count, and other nuclear alterations. 24-hour urine was also collected for the determination of inorganic mercury. Results. 68.7% of participants were male, the mean age being 43 ± 12,4 years (range: 16-76). The average time of occupational exposure to mercury was 12,1 ± 6,7 years, and the contact with mercury was 4,1 ± 3,6 kg per person per day. 93% of participants failed to wear personal protection gear while handling mercury. Results of biological monitoring showed that 17% of participants had concentrations of mercury in urine higher than 2,5 µg/L, this value being the detection limit of the measurement technique used. Results of the genotoxic evaluation evidenced that 15% of people with labor exposure to mercury presented micronuclei in mouth epithelial cells, and other indicators of nuclear alteration such as nucleoplasmic bridges, gemmation and binucleation were found, which are also considered genotoxic events associated to the exposure of physical or chemical risk agents. Conclusions. The finding of micronuclei in mouth epithelial cells reflects genotoxic damage associated to the labor exposure of mercury used in artisanal and small-scale mining activities.


Assuntos
Adolescente , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Mercúrio/toxicidade , Mineração , Exposição Ocupacional/efeitos adversos , Estudos Transversais , Testes de Mutagenicidade
11.
Rev Peru Med Exp Salud Publica ; 30(4): 595-600, 2013.
Artigo em Espanhol | MEDLINE | ID: mdl-24448935

RESUMO

OBJECTIVES: To determine the genotoxic damage among artisanal and small-scale mining workers exposed to mercury. MATERIALS AND METHODS: Observational cross-sectional study which evaluated mercury-exposed workers (n=83), whose cells were collected by mouth swab for further staining, microscopic observance, micronuclei count, and other nuclear alterations. 24-hour urine was also collected for the determination of inorganic mercury. RESULTS: 68.7% of participants were male, the mean age being 43 ± 12,4 years (range: 16-76). The average time of occupational exposure to mercury was 12,1 ± 6,7 years, and the contact with mercury was 4,1 ± 3,6 kg per person per day. 93% of participants failed to wear personal protection gear while handling mercury. Results of biological monitoring showed that 17% of participants had concentrations of mercury in urine higher than 2,5 µg/L, this value being the detection limit of the measurement technique used. Results of the genotoxic evaluation evidenced that 15% of people with labor exposure to mercury presented micronuclei in mouth epithelial cells, and other indicators of nuclear alteration such as nucleoplasmic bridges, gemmation and binucleation were found, which are also considered genotoxic events associated to the exposure of physical or chemical risk agents. CONCLUSIONS: The finding of micronuclei in mouth epithelial cells reflects genotoxic damage associated to the labor exposure of mercury used in artisanal and small-scale mining activities.


Assuntos
Mercúrio/toxicidade , Mineração , Exposição Ocupacional/efeitos adversos , Adolescente , Adulto , Idoso , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Testes de Mutagenicidade , Adulto Jovem
12.
CMAJ ; 180(3): 298-304, 2009 Feb 03.
Artigo em Inglês | MEDLINE | ID: mdl-19188628

RESUMO

BACKGROUND: Clandestine induced abortions are a public health problem in many developing countries where access to abortion services is legally restricted. We estimated the prevalence and incidence of, and risk factors for, clandestine induced abortions in a Latin American country. METHODS: We conducted a large population-based survey of women aged 18-29 years in 20 cities in Peru. We asked questions about their history of spontaneous and induced abortions, using techniques to encourage disclosure. RESULTS: Of 8242 eligible women, 7992 (97.0%) agreed to participate. The prevalence of reported induced abortions was 11.6% (95% confidence interval [CI] 10.9%-12.4%) among the 7962 women who participated in the survey. It was 13.6% (95% CI 12.8%-14.5%) among the 6559 women who reported having been sexually active. The annual incidence of induced abortion was 3.1% (95% CI 2.9%-3.3%) among the women who had ever been sexually active. In the multivariable analysis, risk factors for induced abortion were higher age at the time of the survey (odds ratio [OR] 1.11, 95% CI 1.07-1.15), lower age at first sexual intercourse (OR 0.87, 95% CI 0.84-0.91), geographic region (highlands: OR 1.56, 95% CI 1.23-1.97; jungle: OR 1.81, 95% CI 1.41-2.31 [v. coastal region]), having children (OR 0.82, 95% CI 0.68-0.98), having more than 1 sexual partner in lifetime (2 partners: OR 1.61, 95% CI 1.23-2.09; > or = 3 partners: OR 2.79, 95% CI 2.12-3.67), and having 1 or more sexual partners in the year before the survey (1 partner: OR 1.36, 95% CI 1.01-1.72; > or = 2 partners: OR 1.54, 95% CI 1.14-2.02). Overall, 49.0% (95% CI 47.6%-50.3%) of the women who reported being currently sexually active were not using contraception. INTERPRETATION: The incidence of clandestine, potentially unsafe induced abortion in Peru is as high as or higher than the rates in many countries where induced abortion is legal and safe. The provision of contraception and safer-sex education to those who require it needs to be greatly improved and could potentially reduce the rate of induced abortion.


Assuntos
Aborto Criminoso/estatística & dados numéricos , Aborto Induzido/estatística & dados numéricos , Aborto Criminoso/legislação & jurisprudência , Aborto Induzido/legislação & jurisprudência , Aborto Espontâneo , Adolescente , Adulto , Fatores Etários , Coito , Comportamento Contraceptivo , Feminino , Humanos , Incidência , Análise Multivariada , Peru/epidemiologia , Gravidez , Prevalência , Fatores de Risco , Parceiros Sexuais , Inquéritos e Questionários , Adulto Jovem
13.
La Paz; s.n; 2009. 10 p.
Tese em Espanhol | LIBOCS, LIBOSP | ID: biblio-1336650

RESUMO

Plantea la necesidad de establecer si existe o no responsabilidad por la función pública de la auditoría sumariante, cuando sus fallos son revocados por un órgano jerárquico que condena a la institución el pago de haberes retroactivo, a favor de un servidor público


Assuntos
Bolívia
14.
Rev. imagem ; 30(2): 43-50, abr.-jun. 2008. ilus
Artigo em Português | LILACS | ID: lil-542284

RESUMO

Coccigodínia é uma síndrome dolorosa de difícil abordagem diagnóstica e terapêutica, ainda mal compreendida por clínicos, ortopedistas e radiologistas. No intuito de entender e diferenciar as anormalidades clínico-radiológicas encontradas nas coccigodínias, revisamos a anatomia normal do sacro-cóccix e das demais estruturas pélvicas, suas variações e alterações anatômicas, além doselementos biomecânicos e fisiopatológicos implicados na etiologia da dor. O estudo radiológico funcional do cóccix consiste na obtenção de incidências de perfil nas posições ortostática e sentada, que permite a determinação da mobilidade coccígea. Este método pode demonstrar lesãocausal em 70% dos casos de coccigodínia. A classificação radiológica segundo as alterações da dinâmica do cóccix pode orientar tratamentos e comparar respostas terapêuticas por subgrupos.


Coccygodynia is a painful syndrome still misunderstood by physicians. To understand the radiological abnormalities that may accompanythis syndrome we have revised sacro-coccygeal normal anatomy and its variants and biomechanical elements that may produce pain. Functional radiologic studies of the coccyx consistin lateral projection in upright and sitted positions. Such projections provide clues for the evaluation of coccygeal mobility and may disclose the causal lesion producing coccygodynia in about 70%of the patients. Radiologic classification of the dynamic dysfunctions of coccygeal mobility may orient treatments and compare outcomes in subgroups.


Assuntos
Humanos , Cóccix/anatomia & histologia , Cóccix/fisiopatologia , Cóccix , Diagnóstico por Imagem , Dor , Região Sacrococcígea/anatomia & histologia , Região Sacrococcígea/patologia , Região Sacrococcígea , Síndrome
15.
BMC Med Inform Decis Mak ; 8: 11, 2008 Mar 19.
Artigo em Inglês | MEDLINE | ID: mdl-18366687

RESUMO

BACKGROUND: Low-cost handheld computers (PDA) potentially represent an efficient tool for collecting sensitive data in surveys. The goal of this study is to evaluate the quality of sexual behavior data collected with handheld computers in comparison with paper-based questionnaires. METHODS: A PDA-based program for data collection was developed using Open-Source tools. In two cross-sectional studies, we compared data concerning sexual behavior collected with paper forms to data collected with PDA-based forms in Ancon (Lima). RESULTS: The first study enrolled 200 participants (18-29 years). General agreement between data collected with paper format and handheld computers was 86%. Categorical variables agreement was between 70.5% and 98.5% (Kappa: 0.43-0.86) while numeric variables agreement was between 57.1% and 79.8% (Spearman: 0.76-0.95). Agreement and correlation were higher in those who had completed at least high school than those with less education. The second study enrolled 198 participants. Rates of responses to sensitive questions were similar between both kinds of questionnaires. However, the number of inconsistencies (p = 0.0001) and missing values (p = 0.001) were significantly higher in paper questionnaires. CONCLUSION: This study showed the value of the use of handheld computers for collecting sensitive data, since a high level of agreement between paper and PDA responses was reached. In addition, a lower number of inconsistencies and missing values were found with the PDA-based system. This study has demonstrated that it is feasible to develop a low-cost application for handheld computers, and that PDAs are feasible alternatives for collecting field data in a developing country.


Assuntos
Computadores de Mão , Coleta de Dados/métodos , Adolescente , Adulto , Estudos Transversais , Apresentação de Dados , Feminino , Controle de Formulários e Registros , Humanos , Masculino , Prontuários Médicos , Sistemas Computadorizados de Registros Médicos , Peru , Software , Inquéritos e Questionários , Interface Usuário-Computador
16.
Dermatol. peru ; 12(2): 137-141, 2002. ilus
Artigo em Espanhol | LILACS, LIPECS | ID: lil-475433

RESUMO

La fototerapia con psoralenos y UVA (PUVA) se utiliza en patologías como psoriasis, vitiligo y alopecia areata con resultados satisfactorios, del mismo modo existen otras dermatosis que pueden mejorar con esquemas sistémicos y locales de PUVA entre ellas están: micosis fungoide, eczema atópico, eczema dishidrótico, pustulosis palmo-plantar, histiocitosis X, liquen plano, entre otros. En esta revisión se dan algunos alcances sobre el estado actual del tratamiento PUVA en las dermatosis revisadas.


Assuntos
Fototerapia , Terapia PUVA , Dermatopatias
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