RESUMO
La esporotricosis es la micosis subcutánea más frecuente en todo el mundo; se considera una enfermedad ocupacional; las principales fuentes de infección son la materia vegetal y la madera; puede afectar a todos los grupos etarios, pero predomina en la población adulta. El objetivo es diagnosticar y reportar un caso de esporotricosis cutáneo-linfática. Se describe el caso utilizando el método clínico-epidemiológico y el diagnóstico micológico. Se diagnostica una esporotricosis cutáneo-linfática, lo cual corrobora que el cultivo micológico es el estándar de oro en el diagnóstico de esta micosis. En conclusión, la descripción de este caso, constituye una alerta en el diagnóstico de esta entidad poco frecuente en Cuba(AU)
Sporotrichosis is the most common subcutaneous mycosis worldwide. It is considered an occupational disease whose main sources of infection are vegetal material and wood; it may affect all the age groups but predominant in the adult population. The objective is to diagnose on and report a case of cutaneous-lymphatic sporotrichosis. The case is described on the basis of the clinical and epidemiological method and the mycological diagnosis. Cutaneous-lymphatic sporotrichosis was diagnosed, which confirms that the mycological culture is the golden rule in the diagnosis of this mycosis. In conclusions, the description of this case is an alert to the diagnosis of this rare disease in Cuba(AU)
Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Esporotricose/diagnóstico , Esporotricose/tratamento farmacológicoRESUMO
We report two cases of chromoblastomycosis due to Fonsecaea pedrosoi and F. monophora in otherwise healthy Cuban males. Direct microscopic examination of biopsies revealed muriform cells, the hallmark of chromoblastomycosis. The suspected agents were recovered in culture, identified on the basis of morphological criteria and confirmed by sequencing of the internal transcribed spacer regions of rDNA. Final treatment consisted of surgical excision. The patients were successfully cured since there was no relapse after a follow-up of more than a year. In vitro antifungal susceptibility testing of both isolates showed that itraconazole and posaconazole had potent activity. High MICs of amphotericin B (2 µg/ml), fluconazole (>64 µg/ml), anidulafungin (8 µg/ml) and caspofungin (8 µg/ml) were found.