RESUMO
Background: Ovarian papillary cystadenocarcinoma is a rare neoplasm associated with peritoneal implantation and malignant effusion. Most dogs are asymptomatic until the nodules become large and the abdominal volume is increased. From the clinical suspicion, the diagnosis can be obtained through imaging and histopathology, however, cytological analysis has become an alternative method for the early detection of this neoplasm. In order to demonstrate the importance of cytology in the diagnosis of ovarian neoplasms and its metastasis, it is reported a case of metastatic ovarian papillary cystadenocarcinoma in a dog. Case: Female, intact, teckel, 5-year-old, with increased abdominal volume. Physical examination revealed ascites and intracavitary mass, abdominocentesis and fine needle puncture of the mass were performed for cytological evaluation. In the cavity fluid it was observed: dark red color, cloudy appearance, hematocrit of 35%; (7.6 g / dL), pH (8.0), 22,000 nucleated cells / μL, marked cellularity of pleomorphic epithelial cells arranged in three-dimensional cohesive groups, sometimes in acinar or tubular pattern, nucleus with loose chromatin coarse, scarse to moderate cytoplasm, perinuclear halo, multiple and evident nucleoli compatible with carcinomatous neoplastic effusion. In the cytological evaluation of the tumor, epithelial cells were observed, with the same [...]
Assuntos
Feminino , Animais , Cães , Cistadenocarcinoma Papilar/veterinária , Metástase Neoplásica , Neoplasias Ovarianas/veterinária , Ovário/citologia , Neoplasias/veterinária , Técnicas Citológicas/veterináriaRESUMO
Background: Ovarian papillary cystadenocarcinoma is a rare neoplasm associated with peritoneal implantation and malignant effusion. Most dogs are asymptomatic until the nodules become large and the abdominal volume is increased. From the clinical suspicion, the diagnosis can be obtained through imaging and histopathology, however, cytological analysis has become an alternative method for the early detection of this neoplasm. In order to demonstrate the importance of cytology in the diagnosis of ovarian neoplasms and its metastasis, it is reported a case of metastatic ovarian papillary cystadenocarcinoma in a dog. Case: Female, intact, teckel, 5-year-old, with increased abdominal volume. Physical examination revealed ascites and intracavitary mass, abdominocentesis and fine needle puncture of the mass were performed for cytological evaluation. In the cavity fluid it was observed: dark red color, cloudy appearance, hematocrit of 35%; (7.6 g / dL), pH (8.0), 22,000 nucleated cells / μL, marked cellularity of pleomorphic epithelial cells arranged in three-dimensional cohesive groups, sometimes in acinar or tubular pattern, nucleus with loose chromatin coarse, scarse to moderate cytoplasm, perinuclear halo, multiple and evident nucleoli compatible with carcinomatous neoplastic effusion. In the cytological evaluation of the tumor, epithelial cells were observed, with the same [...](AU)
Assuntos
Animais , Feminino , Cães , Cistadenocarcinoma Papilar/veterinária , Neoplasias Ovarianas/veterinária , Ovário/citologia , Metástase Neoplásica , Neoplasias/veterinária , Técnicas Citológicas/veterináriaRESUMO
O tumor venéreo transmissível (TVT) é uma neoplasia indiferenciada de células redondas queacomete principalmente cães errantes, cuja atividade sexual não é acompanhada. O diagnóstico é realizadobaseando-se nos sinais clínicos e achados citológicos típicos das células esfoliadas. Entretanto, mudanças nascaracterísticas citomorfológicas têm sido observadas, permitindo-se a subdivisão nas classes linfocitóide,plasmocitóide e misto. Autores relataram diferenças na prevalência dos subtipos de TVT de acordo com asregiões brasileiras, porém esse tipo de informação é desconhecida na região Centro-Oeste. O conhecimentodessas informações torna-se imprescindível para o auxílio no diagnóstico e estabelecimento do tratamento eprognóstico apropriados nos animais de cada município e região. O trabalho teve como objetivo caracterizarcitologicamente os casos de TVT canino, diagnosticados em animais atendidos em um hospital escola domunicípio de Campo Grande, Mato Grosso do Sul, Brasil. A partir do diagnóstico de TVT em 70 animais, 88nódulos neoplásicos foram caracterizados por meio da citopatologia. A subclasse plasmocitóide representou81,8% dos casos. A extensa lista de critérios de malignidade, tanto nucleares quanto citoplasmáticos,caracterizaram como malignas todas as amostras estudadas. A presença de mastócitos (32,7%) destacou-se noinfiltrado inflamatório dos nódulos. O padrão observado assemelhou-se aos de outras regiões brasileiras,contudo, as circunstâncias para a frequente presença de mastócitos merecem maiores investigações(AU)
The transmissible venereal tumor (TVT) is an undifferentiated round cell tumor that mainlyaffects stray dogs, whose sexual activity is not monitored. The diagnosis is made based on clinical signs andtypical cytological findings of exfoliated cells. However, changes in cytomorphologic characteristics have beenobserved, allowing the subdivision in lynphocytoid, plasmacytoid and mixed classes. Authors reporteddifferences in the prevalence of TVT subtypes according to the Brazilian regions, however such information isunknown in the region center-west. The knowledge of this information becomes indispensable to aid in thediagnosis and establishment of appropriate treatment and prognosis in animals of each municipality and region.The goal of this paper was to characterize cytologically canine TVT cases, diagnosed in animals of CampoGrande, Mato Grosso do Sul, Brazil. From the diagnosis of TVT in 70 animals, 88 neoplastic nodules werecharacterized by cytopathology. The plasmacytoid subclass represented 81.8% of cases. The extensive list ofmalignancy criteria, both nuclear as cytoplasmic, characterized as malignant all samples. The presence of mastcells (32.7%) stood out in the inflammatory infiltrate of the nodules. The pattern observed was similar to otherbrazilian regions, however, circumstances for frequent presence of mast cells deserves further investigations(AU)
Assuntos
Animais , Cães , Tumores Venéreos Veterinários/patologia , Tumores Venéreos Veterinários/diagnóstico , Gradação de Tumores/veterinária , Neoplasias Urogenitais/veterinária , Técnicas Citológicas/veterinária , Mastócitos/citologiaRESUMO
O tumor venéreo transmissível (TVT) é uma neoplasia indiferenciada de células redondas queacomete principalmente cães errantes, cuja atividade sexual não é acompanhada. O diagnóstico é realizadobaseando-se nos sinais clínicos e achados citológicos típicos das células esfoliadas. Entretanto, mudanças nascaracterísticas citomorfológicas têm sido observadas, permitindo-se a subdivisão nas classes linfocitóide,plasmocitóide e misto. Autores relataram diferenças na prevalência dos subtipos de TVT de acordo com asregiões brasileiras, porém esse tipo de informação é desconhecida na região Centro-Oeste. O conhecimentodessas informações torna-se imprescindível para o auxílio no diagnóstico e estabelecimento do tratamento eprognóstico apropriados nos animais de cada município e região. O trabalho teve como objetivo caracterizarcitologicamente os casos de TVT canino, diagnosticados em animais atendidos em um hospital escola domunicípio de Campo Grande, Mato Grosso do Sul, Brasil. A partir do diagnóstico de TVT em 70 animais, 88nódulos neoplásicos foram caracterizados por meio da citopatologia. A subclasse plasmocitóide representou81,8% dos casos. A extensa lista de critérios de malignidade, tanto nucleares quanto citoplasmáticos,caracterizaram como malignas todas as amostras estudadas. A presença de mastócitos (32,7%) destacou-se noinfiltrado inflamatório dos nódulos. O padrão observado assemelhou-se aos de outras regiões brasileiras,contudo, as circunstâncias para a frequente presença de mastócitos merecem maiores investigações
The transmissible venereal tumor (TVT) is an undifferentiated round cell tumor that mainlyaffects stray dogs, whose sexual activity is not monitored. The diagnosis is made based on clinical signs andtypical cytological findings of exfoliated cells. However, changes in cytomorphologic characteristics have beenobserved, allowing the subdivision in lynphocytoid, plasmacytoid and mixed classes. Authors reporteddifferences in the prevalence of TVT subtypes according to the Brazilian regions, however such information isunknown in the region center-west. The knowledge of this information becomes indispensable to aid in thediagnosis and establishment of appropriate treatment and prognosis in animals of each municipality and region.The goal of this paper was to characterize cytologically canine TVT cases, diagnosed in animals of CampoGrande, Mato Grosso do Sul, Brazil. From the diagnosis of TVT in 70 animals, 88 neoplastic nodules werecharacterized by cytopathology. The plasmacytoid subclass represented 81.8% of cases. The extensive list ofmalignancy criteria, both nuclear as cytoplasmic, characterized as malignant all samples. The presence of mastcells (32.7%) stood out in the inflammatory infiltrate of the nodules. The pattern observed was similar to otherbrazilian regions, however, circumstances for frequent presence of mast cells deserves further investigations