RESUMO
Com o objetivo de identificar os determinantes maternos do consumo de medicamentos na gestação por classes de risco, realizou-se estudo transversal na linha de base de coorte populacional, com 2.262 mães de nascidos vivos em Passo Fundo, Rio Grande do Sul, Brasil. Coleta de dados realizada no Sistema de Informações sobre Nascidos Vivos e mediante entrevistas domiciliares (instrumento adaptado do Maternity Advice Survey). Os medicamentos foram classificados segundo a agência americana Food and Drug Administration. Realizaram-se análises bivariadas e regressão logística seguindo modelo hierarquizado de determinação. Oitenta por cento das mães consumiram pelo menos um medicamento na gestação, distribuídos nas classes de risco: A (53,4 por cento), B (18,1 por cento), C (24,46 por cento), D (1,47 por cento), X (0,06 por cento) e V (vários) (2,1 por cento). Pré-natal incompleto e idade materna < 20 anos determinaram o consumo de medicamentos na classe A e intercorrências na gestação nas classes B, C e D. Na classe C, cesariana e aborto prévio também determinaram o consumo, que na classe V foi independente das variáveis analisadas. Fatores maternos, especialmente intercorrências de saúde, determinam o consumo de medicamentos na gestação sugerindo que seu uso seguro e correto pode ser orientado pelo prescritor.
In order to identify the maternal determinants of the consumption of medication during pregnancy according to risk class, we conducted a population cohort baseline cross-sectional study with 2,262 mothers of liveborn infants in Passo Fundo, Rio Grande do Sul, Brazil. Data were collected from the Information System on Live Births and through home interviews (an instrument adapted from the Maternity Advice Survey). The drugs were classified according to criteria. We conducted bivariate analyses and logistic regression according to the hierarchical model of determination. 80 percent of the mothers consumed at least one medicine during the pregnancy, distributed in risk classes as follows: A (53.4 percent), B (18.1 percent), C (24.46 percent), D (1.47 percent), X (0.06 percent), and V (various) (2.1 percent). Incomplete prenatal care and maternal age < 20 years determined the consumption of medication in class A and pregnancy complications in classes B, C, and D. In class C, cesarean section and previous abortion also determined consumption, which in class V was independent of the variables analyzed. Maternal factors, especially health complications, determine the consumption of medicines during pregnancy, suggesting that the prescribing physician should orient the safe and proper use of such medication.
Assuntos
Humanos , Feminino , Uso de Medicamentos , Nascido Vivo , Gestantes , Brasil , Estudos Transversais , Análise MultivariadaRESUMO
In order to identify the maternal determinants of the consumption of medication during pregnancy according to risk class, we conducted a population cohort baseline cross-sectional study with 2,262 mothers of liveborn infants in Passo Fundo, Rio Grande do Sul, Brazil. Data were collected from the Information System on Live Births and through home interviews (an instrument adapted from the Maternity Advice Survey). The drugs were classified according to criteria. We conducted bivariate analyses and logistic regression according to the hierarchical model of determination. 80% of the mothers consumed at least one medicine during the pregnancy, distributed in risk classes as follows: A (53.4%), B (18.1%), C (24.46%), D (1.47%), X (0.06%), and V (various) (2.1%). Incomplete prenatal care and maternal age < 20 years determined the consumption of medication in class A and pregnancy complications in classes B, C, and D. In class C, cesarean section and previous abortion also determined consumption, which in class V was independent of the variables analyzed. Maternal factors, especially health complications, determine the consumption of medicines during pregnancy, suggesting that the prescribing physician should orient the safe and proper use of such medication.