RESUMO
The proposal of new analytical techniques has guided innovative methodological developments in public health interventions. The goal of this work is show advances in the development of a large scale system for space-time visualization, monitoring, modeling and analysis of epidemic data using a Grid platform. The resulting virtual laboratory, dubbed IntegraEPI, is expected to provide better epidemic forecasting and to define better strategies to fight the spread of a disease, in which new population-level interventions could be evaluated and iteratively refined using computational simulations, with tangible benefits for real-world epidemic prevention and control efforts.
Assuntos
Surtos de Doenças , Informática Médica/organização & administração , Vigilância da População , Brasil , Surtos de Doenças/prevenção & controle , Previsões , HumanosRESUMO
BACKGROUND: Cyclic strabismus, which generally has a 24 hours on-off cycle, is an unusual but interesting form of ocular motor disorder. Cyclic deviations are characterized by periods of significant deviation followed by periods of strict orthotropia. In the orthotropic periods, binocular sensoriality and motricity are normal. During the symptomatic phase, in which the deviation is usually significant and permanent, certain sensory anomalies can be found. Although most referred cases are cyclic esotropia, other cyclic oculomotor disorders have been described. In this report, we present a case with a 24 hours on-off cycle superior oblique paresis that resolved with surgery performed during the alternate day rhythm period. CASE REPORT: A 43 year old woman developed an alternate day hypertropia with bothersome diplopia. During the 24 hour "on" cycles she showed a unilateral left superior oblique paresis. The deviation had onset spontaneously 10 years ago with no previous history of strabismus, surgery or trauma. Following left inferior oblique recession and right inferior rectus recession surgery, the eyes have been straight and the cyclic pattern abolished. CONCLUSION: Cyclic vertical deviation due to a superior oblique paresis can be operated on by means of current surgical procedures in the course of the on-off cycle stage; i.e., before the cyclic pattern has been abolished and the deviation becoming permanent.