RESUMO
Abstract Up until now, there have been few studies of the helminth fauna of Brazilian populations of Pogonias cromis. In North America, P. cromis is known to be a definitive host of Cotylogaster basiri, although there have been no reports of any species of Cotylogaster infecting fish in Brazil. During necropsies of marine fish obtained from professional fisherman in the state of Rio Grande do Sul, Brazil, specimens of C. basiri were found in the intestine and rectum of P. cromis. In comparison with previous studies, differences were found in relation to the number of lobes in the buccal disc and the development of the biocellate larvae in the eggs of C. basiri. This is the first report of C. basiri in P. cromis from Brazil, contributing to the understanding of the helminth fauna of this fish from the coastal zone of Brazil.
Resumo Até a presente data, existem poucos estudos sobre a helmintofauna de Pogonias cromis para o Brasil. Na América do Norte, P. cromis foi registrada como hospedeira de Cotylogaster basiri e, até o presente momento, não existem registros de qualquer espécie de Cotylogaster em peixes no Brasil. Em necropsias de peixes marinhos adquiridos por pescadores profissionais, foram encontrados espécimes de C. basiri no intestino e reto de P. cromis no Estado do Rio Grande do Sul, Brasil. Quando comparada com a literatura, foram encontradas diferenças em relação ao número de lobos do funil oral e ao desenvolvimento da larva biocelar dentro dos ovos de C. basiri. Este é o primeiro registro de C. basiri em P. cromis para o Brasil, contribuindo para o conhecimento da helmintofauna desse peixe na costa brasileira.
Assuntos
Animais , Infecções por Trematódeos/parasitologia , Perciformes/parasitologia , BrasilRESUMO
Up until now, there have been few studies of the helminth fauna of Brazilian populations of Pogonias cromis. In North America, P. cromis is known to be a definitive host of Cotylogaster basiri, although there have been no reports of any species of Cotylogaster infecting fish in Brazil. During necropsies of marine fish obtained from professional fisherman in the state of Rio Grande do Sul, Brazil, specimens of C. basiri were found in the intestine and rectum of P. cromis. In comparison with previous studies, differences were found in relation to the number of lobes in the buccal disc and the development of the biocellate larvae in the eggs of C. basiri. This is the first report of C. basiri in P. cromis from Brazil, contributing to the understanding of the helminth fauna of this fish from the coastal zone of Brazil.(AU)
Até a presente data, existem poucos estudos sobre a helmintofauna de Pogonias cromis para o Brasil. Na América do Norte, P. cromis foi registrada como hospedeira de Cotylogaster basiri e, até o presente momento, não existem registros de qualquer espécie de Cotylogaster em peixes no Brasil. Em necropsias de peixes marinhos adquiridos por pescadores profissionais, foram encontrados espécimes de C. basiri no intestino e reto de P. cromis no Estado do Rio Grande do Sul, Brasil. Quando comparada com a literatura, foram encontradas diferenças em relação ao número de lobos do funil oral e ao desenvolvimento da larva biocelar dentro dos ovos de C. basiri. Este é o primeiro registro de C. basiri em P. cromis para o Brasil, contribuindo para o conhecimento da helmintofauna desse peixe na costa brasileira.(AU)
Assuntos
Animais , Trematódeos/anatomia & histologia , Trematódeos/classificação , Perciformes/parasitologia , Interações Hospedeiro-Parasita , BrasilRESUMO
Up until now, there have been few studies of the helminth fauna of Brazilian populations of Pogonias cromis. In North America, P. cromis is known to be a definitive host of Cotylogaster basiri, although there have been no reports of any species of Cotylogaster infecting fish in Brazil. During necropsies of marine fish obtained from professional fisherman in the state of Rio Grande do Sul, Brazil, specimens of C. basiri were found in the intestine and rectum of P. cromis. In comparison with previous studies, differences were found in relation to the number of lobes in the buccal disc and the development of the biocellate larvae in the eggs of C. basiri. This is the first report of C. basiri in P. cromis from Brazil, contributing to the understanding of the helminth fauna of this fish from the coastal zone of Brazil.
Assuntos
Perciformes/parasitologia , Infecções por Trematódeos/parasitologia , Animais , BrasilRESUMO
This work reports the preparation of dexamethasone in nanoparticle-coated microparticles and the study of the influence of such microencapsulation on drug absorption across Caco-2 cell monolayers. Nanoparticle-coated microparticles were prepared by spray-drying using nanocapsules (NC) or nanospheres (NS) in aqueous suspensions as coating material. Drug contents ranged from 64 to 134mgg(-1), yields between 49% and 67% and moisture content below 2.0%. SEM and AFM analysis demonstrated that the nanoparticle-coated microparticles (20-53microm) show nanostructures on their surface with a similar diameter compared to the aqueous suspensions. The type of nanocoating material had a significant influence on the drug release profile and on the drug permeation across Caco-2 cells: NC-coated microparticles led to a prolonged release and slower transport across Caco-2 cell monolayers, while the NS-coated microparticles showed a faster release and Caco-2 transport compared to uncoated microparticles. The correlation between the amount of drug permeated and the drug released (%) suggests that the drug absorption from such a delivery system is controlled mainly by the release rate rather than by epithelial permeability. Caco-2 transport studies appear to be a useful characterization tool for the development of microparticulate oral controlled release systems.