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INTRODUCTION: Incontinentia pigmenti or Bloch-Sulzberger syndrome is a rare X-linked dominant disease that mainly affects the skin, eyes, hair, central nervous system and teeth. The disease is predominant among women. Although dermatologic manifestations are among the most important aspects for the diagnosis of the syndrome, they are less damaging to the patient and do not require treatment. However, oral involvement characterized by hypodontia of deciduous and permanent teeth is important for the diagnosis and treatment of the patient. CASE PRESENTATION: We report the case of a 3-year-old girl with ophthalmologic and neurologic disturbances, cutaneous manifestations and hypodontia. Since the patient did not present more damaging manifestations such as neurologic and/or ophthalmologic problems, her most severe complications were related to dental anomalies. The importance of integrated dental treatment, which combines pediatric dentistry, orthodontics and conventional prosthesis, is emphasized. CONCLUSION: Hypodontia is a frequent finding in incontinentia pigmenti, and dentists should be aware of this condition in order to help with the diagnosis.
RESUMO
OBJECTIVE: To compare exfoliative cytology from the oral mucosa of smokers and nonsmokers, with emphasis on proliferative activity. METHODS: Exfoliative cytology specimens were obtained from clinical normal mucosa from the lateral border of the tongue in 30 nonsmokers and 30 smokers ranging in age from 40 to 70 years of age, who were seen at the Heart Institute's Patient Center and the Smoking Cessation Program of the University Hospital, University of São Paulo Medical School (InCor-HCFMUSP). The cytologic specimens were evaluated by Papanicolaou staining and AgNOR quantification in order to evaluate the presence of cytological alterations suggestive of inflammation, dysplasia, keratinization, and proliferative activity of epithelial cells. RESULTS: Only Papanicolaou Class I and Class II smears were observed. Inflammatory alterations were found in 90% of smokers and in 87% of nonsmokers. The number of AgNORs/nucleus differed significantly between smokers and nonsmokers (3.372 +/- 0.375 versus 2.732 +/- 0.236). CONCLUSIONS: Within the limitations of this research, the results indicate higher proliferative activity in smoking patients compared to nonsmoking patients, even in the absence of clinical lesions.
Assuntos
Antígenos Nucleares/metabolismo , Mucosa Bucal/patologia , Região Organizadora do Nucléolo/patologia , Fumar/efeitos adversos , Coloração e Rotulagem/métodos , Doenças da Língua/patologia , Adulto , Idoso , Antígenos Nucleares/química , Proliferação de Células/efeitos dos fármacos , Citodiagnóstico/métodos , Humanos , Masculino , Pessoa de Meia-Idade , Mucosa Bucal/metabolismo , Região Organizadora do Nucléolo/metabolismo , Reprodutibilidade dos Testes , Coloração pela Prata , Doenças da Língua/etiologiaRESUMO
BACKGROUND: Sporotrichosis is a granulomatous fungal infection caused by Sporothrix schenckii, which frequently causes cutaneous or lymphocutaneous lesions and rarely has oral manifestations. CASE: A 38-year-old, white, HIV-positive man complained of a 5.0-cm, symptomatic, ulcerated lesion with thin, superficial granulation in the soft palate extending to the uvula. Exfoliative cytology of this oral lesion showed chronic granulomatous inflammatory alterations and extracellular fungal structures consisting of periodic acid-Schiff-positive budding cells and spherical or elongated (cigar bodies) free spore forms. CONCLUSION: The clinical and cytologic findings allowed the diagnosis of sporotrichosis, demonstrating the importance of cytodiagnosis in fungal diseases.
Assuntos
Soropositividade para HIV/complicações , Soropositividade para HIV/microbiologia , Doenças da Boca/complicações , Doenças da Boca/microbiologia , Esporotricose/complicações , Adulto , Células Epiteliais/patologia , Humanos , Masculino , Mucosa Bucal/patologiaRESUMO
Atualmente, muito tem se discutido sobre a natureza pré-maligna do líquen plano oral. Embora novas linhas de pesquisa tenham sido desenvolvidas nos últimos anos, estamos longe de alcançar um consenso. Se por um lado, estudos recentes afastam a possibilidade de transformação do líquen plano oral em carcinoma epidermóide, por outro, não são poucos os casos relatados na literatura que enfatizam esse potencial.O presente trabalho tem por objetivo traçar um perfil comparativo entre os casos de líquen plano e o carcinoma epidermóide em mucosa bucal dos arquivos de Patologia Cirúrgica da Disciplina de Patologia Bucal da Faculdade de Odontologia de São José dos Campos - UNESP, na tentativa de se estabelecer uma possível correlação entre ambos