1.
Ginecol Obstet Mex
; 67: 267-71, 1999 Jun.
Artigo
em Espanhol
| MEDLINE
| ID: mdl-10416303
RESUMO
The partnership the insulin-like growth factor (IGF) in women with polycystic ovary syndrome (PCOS) is characterized by mechanisms underlying alterations in the GH/IGF-1, axis. In the pathogenesis exist a synergism markedly enhanced between IGF-1 and insulin, and IGF-1 with LH to increase androgen production, causing a reduced IGFBPs and SHBG production, the resulting hyperandrogenism, within and outside the ovary, may inhibitor follicular maturation and the biosynthesis of estrogen. At the present, the data suggests up to date paracrine, autocrine as well as endocrine actions in the ovary in normal conditions and the lost of this homeostasis can be followed by neuro-endocrine.
Assuntos
Síndrome do Ovário Policístico/metabolismo , Somatomedinas/metabolismo , Adulto , Feminino , Humanos , Pessoa de Meia-Idade , Somatomedinas/análise
2.
México; Editorial Medica Panamericana; 1995. 314 p. ilus.
Monografia
em Espanhol
| LILACS
| ID: lil-374683
3.
Ginecol Obstet Mex
; 30(181): 567-75, 1971 Nov.
Artigo
em Espanhol
| MEDLINE
| ID: mdl-5131139