RESUMO
Symptomatic therapy in Sydenham's chorea has not been satisfactory. Perphenazine was tested as an alternative to diminish abnormal movements. A Syndenham's chorea comparative double-blind study (17 patients) using it, with reserpine and placebo as controls, was designed. Perphenazine was tried also in another open-study (13 patients with Syndenham's chorea). Out of the 2 groups, those which received perphenazine improved earlier and in a greater proportion than controls, with statistical significance (p is less than 0.01).
Assuntos
Coreia/tratamento farmacológico , Perfenazina/uso terapêutico , Adolescente , Criança , Pré-Escolar , Ensaios Clínicos como Assunto , Método Duplo-Cego , Avaliação de Medicamentos , Feminino , Humanos , Masculino , Placebos , Reserpina/uso terapêutico , Febre Reumática/complicaçõesRESUMO
Results of 12 late synovectomies in juvenile rheumatoid arthritis (JRA) (6 knees, 5 wrists, 1 hip), have been evaluated. Synovectomies we performed in 5 patients with 7 to 11 years of evolution and with advanced joint lesions at the X-rays. Pain and inflammation disappeared in all synovectomized joints, but one year later the range of motion was slightly decreased in most of them. In the operated hip, the extent of motions decreased at first, but 6 years later it worked better than the opposite. It is concluded that synovectomy in JRA is useful, even with advanced joint lesions. For best results, present day criteria is to perform synovectomy early in the course of the disease.
Assuntos
Artrite Juvenil/cirurgia , Sinovectomia , Adolescente , Artrite Juvenil/diagnóstico por imagem , Criança , Feminino , Quadril/diagnóstico por imagem , Quadril/cirurgia , Humanos , Joelho/cirurgia , Masculino , Radiografia , Membrana Sinovial/diagnóstico por imagem , Punho/cirurgiaRESUMO
The clinical records of 13 school-age children and of 22 adolescents with chronic peptic ulcer were reviewed. There was a predominance of the male sex and duodenal localization showed greater frequency than the gastric. The duration of symptoms previous to the diagnosis was greater in adolescents and repeated X-ray studies were required in school-agers to confirm the presence of an ulcer niche. The common symptoms were abdominal pain and vomiting. However, in 43% of the patients, abdominal pain was not typical of ulcer; therefore, all school-age children and adolescents with recurrent abdominal pain should be submitted to careful investigation. Anxiety and depression were found in 92.3% of the cases. Special ulcer diets and antiacids were given to all patients, but 8 cases showed no improvement. Psychiatric treatment and administration of psychodrugs may be useful. Diazepam was given to 50% of the patients who recovered and to one who did not recover.
Assuntos
Úlcera Péptica/epidemiologia , Adolescente , Fatores Etários , Antiácidos/uso terapêutico , Criança , Doença Crônica , Dietoterapia , Úlcera Duodenal/tratamento farmacológico , Úlcera Duodenal/epidemiologia , Feminino , Humanos , Masculino , México , Serviços de Saúde Escolar , Úlcera Gástrica/tratamento farmacológico , Úlcera Gástrica/epidemiologiaRESUMO
Six children with abscess of the psoas muscle are presented. Previous trauma pain, claudication and antalgic position of a lower limb, fever, abdominal tenderness and leukocytosis were prominet features. Four patients improved and two died. Treatment included surgical drainage and antibiotics. Differential diagnosis and possible pathogenesis are discussed.
Assuntos
Abscesso/microbiologia , Região Lombossacral , Doenças Musculares/microbiologia , Abscesso/tratamento farmacológico , Abscesso/cirurgia , Adolescente , Antibacterianos/uso terapêutico , Bactérias/isolamento & purificação , Criança , Pré-Escolar , Diagnóstico Diferencial , Drenagem , Feminino , Humanos , Masculino , Doenças Musculares/tratamento farmacológico , Doenças Musculares/cirurgiaRESUMO
Some characteristics of juvenile rheumatoid arthritis that appeared in recent literature have led us to think that it can be divided into the following four groups: I. Seronegative poliarthritis, with more or less systemic symptoms. With the same characteristics it may appear in adulthood. II. Seropositive poliarthritis, identical to the adult rheumatoid arthritis. III. B-27 negative oligoarthritis, complicated frequently with chronic uveitis and autolimited course. IV. B-27 positive oligoarthritis evolving to ankylosing spondylitis. These groups may represent different diseases.