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Ginecol Obstet Mex ; 61: 76-9, 1993 Mar.
Artigo em Espanhol | MEDLINE | ID: mdl-8454221

RESUMO

The objective was to compare the fetal and maternal effects between parenteral hydralazine and sublingual nifedipine used like antihypertensive drugs in the management of severe preeclampsia. Study design was prospective, comparative, longitudinal, randomized clinical trial. It was carried out at Centro Medico Nacional IMSS Torreon, Coah. Gynecology and Obstetrics Department. The patients were women in the last trimester of pregnancy with severe preeclampsia were randomized to receive parenteral hydralazine or sublingual nifedipine as antihypertensive drugs. The only difference observed in this study was the Apgar of neonates whose mothers received hydralazine, that was significatively lesser than the Apgar of neonates whose mothers received nifedipine. Both medicaments are a good alternative as antihypertensive drugs in severe preeclampsia. Neonates whose mothers received Nifedipine had a higher Apgar.


Assuntos
Eclampsia/tratamento farmacológico , Hidralazina/administração & dosagem , Nifedipino/administração & dosagem , Pré-Eclâmpsia/tratamento farmacológico , Administração Sublingual , Anti-Hipertensivos/administração & dosagem , Índice de Apgar , Avaliação de Medicamentos , Feminino , Humanos , Recém-Nascido , Infusões Parenterais , Estudos Longitudinais , Gravidez , Terceiro Trimestre da Gravidez , Efeitos Tardios da Exposição Pré-Natal , Estudos Prospectivos
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