RESUMO
OBJECTIVE: To evaluate two different criteria, one or two cut-off values, of oral glucose tolerance test with 75g of glucose for the diagnosis of gestational diabetes mellitus. METHODS: A cross-sectional study involving 120 records of pregnant women who received prenatal care at the service of a Brazilian university was carried out. Bivariate analysis of obstetric and perinatal outcomes was performed using the chi-square test. RESULTS: Considering criterion I, 12.5% of patients were diagnosed with gestational diabetes mellitus. Patients were 3.57 times more likely to have a large fetus for the gestational age at birth (p=0.038). Using criterion II, gestational diabetes mellitus was diagnosed in 5.8% of patients, macrosomia was 7.73 times more likely to be found in the presence of gestational diabetes mellitus (p=0.004), and a large fetus for the gestational age at birth was 8.17 times more likely (p=0.004). CONCLUSIONS: There was a difference in the prevalence of gestational diabetes mellitus between the two criteria analyzed. The new criterion proposed increased prevalence.
Assuntos
Diabetes Gestacional/diagnóstico , Teste de Tolerância a Glucose/normas , Adulto , Brasil/epidemiologia , Estudos Transversais , Diabetes Gestacional/epidemiologia , Feminino , Idade Gestacional , Teste de Tolerância a Glucose/métodos , Humanos , Gravidez , Cuidado Pré-Natal/métodos , Prevalência , Padrões de Referência , Fatores de Risco , Fatores de Tempo , Adulto JovemRESUMO
SUMMARY OBJECTIVE To evaluate two different criteria, one or two cut-off values, of oral glucose tolerance test with 75g of glucose for the diagnosis of gestational diabetes mellitus. METHODS A cross-sectional study involving 120 records of pregnant women who received prenatal care at the service of a Brazilian university was carried out. Bivariate analysis of obstetric and perinatal outcomes was performed using the chi-square test. RESULTS Considering criterion I, 12.5% of patients were diagnosed with gestational diabetes mellitus. Patients were 3.57 times more likely to have a large fetus for the gestational age at birth (p=0.038). Using criterion II, gestational diabetes mellitus was diagnosed in 5.8% of patients, macrosomia was 7.73 times more likely to be found in the presence of gestational diabetes mellitus (p=0.004), and a large fetus for the gestational age at birth was 8.17 times more likely (p=0.004). CONCLUSIONS There was a difference in the prevalence of gestational diabetes mellitus between the two criteria analyzed. The new criterion proposed increased prevalence.
RESUMO OBJETIVO Avaliar dois critérios distintos, um ou dois valores de corte, do teste oral de tolerância à glicose com 75 g de glicose para o diagnóstico de diabetes mellitus gestacional. Métodos Estudo transversal envolvendo 120 prontuários de gestantes que realizaram pré-natal em um ambulatório de uma universidade brasileira. Análise bivariada dos resultados obstétricos e perinatais foi realizada pelo teste do qui-quadrado. Resultados Considerando o critério I, 12,5% das pacientes foram diagnosticadas com diabetes mellitus gestacional. As pacientes apresentaram uma chance 3,57 maior de ter um feto grande para a idade gestacional (p=0,038). Utilizando o critério II, o diabetes mellitus gestacional foi diagnosticado em 5,8% das pacientes. Mediante esse critério diagnóstico, a chance de macrossomia foi 7,73 vezes mais provável na presença de diabetes mellitus gestacional (p=0,004) e a chance de um feto grande para a idade gestacional foi 8,17 vezes maior de ocorrer (p=0,004). Conclusões Observou-se diferença na prevalência de diabetes melittus gestacional entre os dois critérios analisados, sendo que o novo critério proposto aumentou a prevalência.
Assuntos
Humanos , Feminino , Gravidez , Adulto , Adulto Jovem , Diabetes Gestacional/diagnóstico , Teste de Tolerância a Glucose/normas , Cuidado Pré-Natal/métodos , Padrões de Referência , Fatores de Tempo , Brasil/epidemiologia , Prevalência , Estudos Transversais , Fatores de Risco , Idade Gestacional , Diabetes Gestacional/epidemiologia , Teste de Tolerância a Glucose/métodosRESUMO
INTRODUCTION: Cancer of the lip, mouth and pharynx is a serious health problem. High incidence rates are found worldwide. In Brazil, the Southern and Southeastern regions have the highest incidences in the country. OBJECTIVE: To describe 5 and 10-year survival rates in patients with cancer of the lip, mouth and pharynx at a referral center in Florianopolis, Santa Catarina, Brazil. METHODS: Retrospective cohort study using data from patients diagnosed between January 1st and December 31st, 2001, with follow-up until December 31st, 2011. Descriptive analysis was performed and survival was estimated by Kaplan-Meier method. Cox semi-parametric model was used to estimate death risk. RESULTS: Survival rates at 5 and 10 years were 33.3 and 26.9%, respectively. Advanced clinical stage in the diagnosis increased death risk by 2.88 and 2.51, respectively. Sex, ethnicity, level of education, previous diagnosis and treatment, as well as age, did not show significant association. CONCLUSION: Survival rate at 5 years was 33.3% and, at 10 years, was 26.9%. Advanced stage was an independent risk factor for death due to cancer of the lip, mouth and pharynx in both periods analyzed.
Assuntos
Neoplasias Labiais/mortalidade , Neoplasias Bucais/mortalidade , Neoplasias Faríngeas/mortalidade , Estudos de Coortes , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Taxa de Sobrevida , Fatores de TempoRESUMO
Introduction: Cancer of the lip, mouth and pharynx is a serious health problem. High incidence rates are found worldwide. In Brazil, the Southern and Southeastern regions have the highest incidences in the country. Objective: To describe 5 and 10-year survival rates in patients with cancer of the lip, mouth and pharynx at a referral center in Florianopolis, Santa Catarina, Brazil. Methods: Retrospective cohort study using data from patients diagnosed between January 1st and December 31st, 2001, with follow-up until December 31st, 2011. Descriptive analysis was performed and survival was estimated by Kaplan-Meier method. Cox semi-parametric model was used to estimate death risk. Results: Survival rates at 5 and 10 years were 33.3 and 26.9%, respectively. Advanced clinical stage in the diagnosis increased death risk by 2.88 and 2.51, respectively. Sex, ethnicity, level of education, previous diagnosis and treatment, as well as age, did not show significant association. Conclusion: Survival rate at 5 years was 33.3% and, at 10 years, was 26.9%. Advanced stage was an independent risk factor for death due to cancer of the lip, mouth and pharynx in both periods analyzed. .
Introdução: O câncer de lábio, boca e faringe é um sério problema de saúde. Altas taxas de incidência são encontradas no mundo. No Brasil, as regiões Sul e Sudeste são as que apresentam maiores taxas de incidência. Objetivo: Descrever a taxa de sobrevida em cinco e dez anos em portadores de câncer de lábio, boca e faringe atendidos em um centro de referência de Florianópolis, SC. Métodos: Estudo de coorte histórica, realizado com dados de pacientes que tiveram diagnóstico entre 1º de janeiro e 31 de dezembro de 2001 e acompanhados até 31 de dezembro de 2011. Foi realizada análise descritiva e estimada a sobrevida pelo método de Kaplan-Meier. O modelo semiparamétrico de Cox foi utilizado para estimar o risco de óbito. Resultados: As taxas de sobrevida ao final de 5 e 10 anos foram de 33,3 e 26,9%, respectivamente. O estadio clínico avançado ao momento do diagnóstico aumentou em 2,88 e 2,51 o risco de óbito, respectivamente. Sexo, etnia, nível de escolaridade, diagnóstico e tratamento prévios, bem como idade, não se mostraram significativamente associados. Conclusão: As taxas de sobrevida aos 5 anos foi de 33,3% e, aos 10 anos, foi de 26,9%. O estadio avançado mostrou-se como fator de risco independente para o óbito por câncer de lábio, boca e faringe nos dois períodos analisados. .