1.
J Org Chem
; 85(18): 11663-11678, 2020 09 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32852210
RESUMO
A transition metal- and oxidant-free visible light-photoinduced protocol for direct functionalization of 2-methylquinolines has been developed. This protocol enabled the C-H functionalization of substituted 2-methylquinolines with diacetyl or ethyl pyruvate, under environmentally friendly conditions. A mechanistic investigation based on density functional theory (DFT) calculations provided details about the origins of reactivity and selectivity.