RESUMO
Abstract Objective: Dentistry from the Universidade Federal de Alfenas who were enrolled in the seventh period and who took the Integrated Clinic I Discipline (ICID) in the emergency remote learning model (ERLM). Material and Methods: This is a qualitative and descriptive study. The information was collected through questionnaires applied by the Professors during the ICID. Subsequently, the professor evaluated the treatment developed in virtual form by each student regarding its logical sequence and the most appropriate treatment for each case. The results of the answers were transcribed and submitted to lexicographical textual, Descending Hierarchical Classification, and Similitude analysis in the Interface de R pour les Analyses Multidimensionnelles de Textes et de Questionnaires (IRAMUTEQ) program. Results: The students described the online situational treatment planning in five essential steps: adequacy of the oral environment, restorative need, prosthetic need, rehabilitation by prosthesis on the implant, and corrective orthodontic treatment. Conclusion: It was observed that the students who enrolled in ICID presented well-integrated planning during ERLM, despite the COVID-19 pandemic hindering these students' contact between theoretical teaching and the integrated practices in dentistry offered by the educational institution.
Assuntos
Humanos , Masculino , Feminino , Estudantes de Odontologia , Conhecimentos, Atitudes e Prática em Saúde , Clínicas Odontológicas , Pesquisa Qualitativa , Inquéritos e QuestionáriosRESUMO
ABSTRACT Objective: To determine the prevalence and risk factors associated with dental caries in Brazilian preschool children aged 2 to 5 years. Material and Methods: The following independent variables were evaluated: dental caries, dental trauma, and malocclusions. Data were analyzed using the Mann-Whitney test and Poisson regression (p<0.05). Results: The prevalence of dental caries in preschoolers was 55.1%. Child age, family income, maternal education, and tooth color alteration from trauma were significantly associated with dental caries (p<0.05). The final adjusted multivariate model showed a significant association between maternal education and dental caries; children of mothers with low education were 1.89 times more likely to have caries (PR: 1.89; 95%CI: 1.40-2.55) (p<0.01). Children with tooth color change from trauma were more likely to have dental caries (PR: 1.69; 95%CI: 1.22-2.34 (p=0.001). Conclusion: Child age, family income, maternal education, tooth discoloration and discoloration color are risk factors for the development of caries disease in children. Also, children of mothers with low educational levels have a higher chance of developing dental caries.
Assuntos
Masculino , Feminino , Pré-Escolar , Saúde Bucal/educação , Traumatismos Dentários/diagnóstico , Assistência Odontológica para Crianças , Cárie Dentária/prevenção & controle , Fatores Socioeconômicos , Modelos Logísticos , Distribuição de Poisson , Estudos Transversais/métodos , Análise Multivariada , Fatores de Risco , Estatísticas não ParamétricasRESUMO
OBJECTIVE: This cohort study was to investigate maternal knowledge of the oral health of woman and children during pregnancy and after childbirth, and the associated factors. METHODS: Groups of women participating in a public prenatal dental care programme in Brazil were assessed, in two different stages. In the first stage, pregnant women were assessed for their own oral health. In the second stage, after childbirth, women were assessed for the oral health of their child. The examiner assigned a maternal knowledge score to the questionnaires, considering the ideal alternatives within the context of oral health promotion as correct answers. Statistical analysis included the Kruskal-Wallis and multiple linear regression tests, considering a level of significance of P < 0.05. RESULTS: Ninety-eight women were included in the study, with a mean age 26.27 years (SD 6.51). In the regression analysis, the maternal knowledge score was associated with the presence of myths about oral health (P < 0.01), the children first dental appointment in the first year of life (P = 0.07), the presence of a non-nutritious sucking habit (P < 0.01), considering dental treatment to be important during pregnancy (P < 0.01), and having been instructed on oral health during pregnancy (P < 0.01) and after the children birth (P = 0.02). CONCLUSION: This study suggests that the women showed a regular score of knowledge about their oral health and that of their children, as they still believed in some myths about oral health and the risks of dental treatment during pregnancy. Women who received guidance on oral health in pregnancy and after birth showed higher knowledge of their oral health and that of their children, demonstrating the importance of carrying out health promotion actions during pregnancy and the first years of the child's life.
Assuntos
Saúde Bucal , Gestantes , Criança , Feminino , Gravidez , Humanos , Adulto , Estudos de Coortes , Parto , MãesRESUMO
ABSTRACT Objective: To evaluate the oral health and related factors among people with visual impairment in a municipality in southeastern Brazil. Methods: A cross-sectional and descriptive household study was carried out on a representative sample of people with visual impairments in a medium-sized city in Brazil. A clinical-dental examination was performed (evaluating tooth loss, caries, periodontal health, dental plaque use and need of prosthesis) and a semistructured questionnaire was applied, investigating the socioeconomic conditions (sex, age, marital status, skin color and income) and the use of dental services (reason, time since, and type of service used [private/public] in last dental visit). Descriptive and bivariate analysis were performed to asses the factors related to oral health. Results: The mean age of participants was 65 years (±15.05), with the majority women (70.9%). 53.1% of the interviewees were edentulous, but 58.2% had a good perception of oral health. The blind ones use less public services (p=0.038) and with a lower frequency (p=0.014) than subjects with low vision. Those with less schooling had higher tooth loss and lower periodontal problems (p <0.05). There was a reduction of dental plaque six months after the educational action (30.7%; p=0.01), especially among the low vision participants (p=0.01). Conclusion: Severe tooth loss and unsatisfactory hygiene contrast with self-perception of oral health. Visual acuity and schooling were related to access and oral health. Actions for promotion and equity are necessary to overcome the inequalities encountered.
RESUMO Objetivo: Avaliar a saúde bucal e fatores relacionados entre deficientes visuais em município do sudeste brasileiro. Métodos: Foi realizado um estudo domiciliar, transversal e descritivo em uma amostra representativa de pessoas com deficiência visual em uma cidade de médio porte do Brasil. Realizou-se o exame clínico bucal (avaliando perda dentária, cárie, saúde periodontal, placa dentária, uso e necessidade de prótese) e aplicou-se um questionário semiestruturado, investigando as condições socioeconômicas (sexo, idade, estado civil, cor da pele e renda) e o uso de serviços odontológicos (motivo, tempo decorrido e tipo de serviço utilizado [privado/público] na última consulta odontológica). Foram realizadas análises descritivas e bivariadas para avaliar os fatores associados à saúde bucal. Resultados: A idade média dos participantes foi de 65 anos (±15,05), com maioria de mulheres (70,9%). 53,1% dos entrevistados eram edêntulos, porém, 58,2% apresentaram percepção de saúde bucal boa. Os cegos usam menos os serviços públicos (p=0,038) e em menor frequência (p=0,014) que os sujeitos com baixa visão. Os menos escolarizados apresentam maiores perdas dentárias e menores problemas periodontais (p<0,05). Houve redução de placa dentária seis meses após ação educativa (30,7%; p=0,01), sobretudo entre os sujeitos com baixa visão (p=0,01). Conclusão: Elevada perda dentária e higienização insatisfatória contrastaram com autopercepção dos agravos bucais. Acuidade visual e escolaridade relacionaram-se ao acesso e saúde bucal. Ações de promoção e equidade são necessários para superar desigualdades encontradas.
RESUMO
Resumo Introdução Pacientes com insuficiência renal crônica podem apresentar prejuízos em sua saúde bucal em decorrência da própria doença, do tratamento e das alterações de estilo de vida associadas. Objetivo Avaliar os fatores associados à autoavaliação de saúde bucal ruim entre adultos com insuficiência renal crônica submetidos à hemodiálise. Método Estudo transversal com 243 adultos submetidos à hemodiálise em um hospital do sul de Minas Gerais nos anos de 2013 e 2014. O desfecho foi avaliado pelo autorrelato da condição bucal dicotomizada em boa (ótima/boa) e ruim (regular/ruim/péssima). As variáveis independentes incluíram condições sociodemográficas, saúde geral, saúde bucal e uso de serviços odontológicos, a partir de informações coletadas por meio de questionário. A associação entre o desfecho e as variáveis independentes foi testada por meio de modelos logísticos múltiplos com inclusão hierarquizada de variáveis. Resultados A prevalência de autoavaliação de saúde bucal ruim foi de 35,4%. Os mais jovens (p = 0,015), os que se submetem à hemodiálise há menos tempo (p = 0,016), têm halitose (p <0,001), necessitam de tratamento odontológico (p <0,001) e tiveram a última consulta odontológica por motivo diferente de dor (p = 0,027) expressaram maiores chances de autoavaliação de saúde bucal ruim, independentemente de condições sociodemográficas e de saúde. Conclusão Condições sociodemográficas, tempo em hemodiálise, agravos à saúde bucal e uso de serviços odontológicos influenciaram a autoavaliação da saúde bucal dos adultos submetidos à hemodiálise.
Abstract Background Patients with chronic renal failure may have their oral health impaired as a result of the disease itself, its treatment, and its associated lifestyle alterations. Objective To assess the factors associated with poor self-rated oral health among adults with chronic renal failure treated by hemodialysis. Method This is a cross-sectional study with 243 adults undergoing hemodialysis in a hospital in Minas Gerais, Brazil in 2013-2014. The outcome was assessed by the self-report of oral health categorized into good (excellent/good) and bad (fair/bad / very bad). The independent variables included sociodemographic conditions, general health, oral health, and the use of dental services were collected through a structured questionnaire. The association between the outcome and the independent variables was tested using multiple logistic models with hierarchical inclusion of variables. Results The prevalence of poor self-rated oral health was 35.4%. The youngest (p = 0.015), those who have undergone hemodialysis in the shortest time (p = 0.016), have halitosis (p <0.001), need dental treatment (p <0.001), and had their last dental appointment not for pain (p = 0.027) expressed higher odds of poor self-rated oral health, independently of sociodemographic and health conditions. Conclusion Sociodemographic conditions, time on hemodialysis, oral impairments, and use of dental services affected the oral health self-assessment among adults undergoing hemodialysis.
RESUMO
PURPOSE: This study evaluated the systemic and local effects of doxycycline (DOX) and low-intensity laser (LIL) treatment as adjuvants to scaling and root planing (SRP) in the treatment of experimental periodontitis in rats. METHODS: The sample consisted of 180 male rats (Rattus norvegicus albinus, Wistar), of which 30 did not receive induction of periodontal disease (negative control [NC] group) and 150 received induction of periodontal disease in the lower first molar. After 7 days, the ligature was removed, and the animals were divided into the following groups: NT (no treatment), SRP (SRP), DOX (SRP and DOX irrigation), LIL (SRP and laser irradiation), and DOX+LIL (SRP, DOX, and LIL). The animals were euthanized at 7, 15, and 30 days; thereafter, biochemical, radiographic, histological, and immunohistochemical analyses were performed. RESULTS: In the intragroup analysis, lower concentrations of α-1-glycoprotein acid (α-1-Ga) and complement 3 (C3) were observed in the DOX+LIL group than in all other groups at all time points, as well as lower levels of complement 4 (C4) at 15 and 30 days (P<0.001). Less bone loss was observed in the DOX, LIL, and DOX+LIL groups than in the NC and SRP groups at all time points (P<0.001). There was a smaller number of tartrate-resistant acid phosphatase (TRAP)-positive cells in the DOX+LIL group than in the other groups at all time points (P<0.001). Positive correlations were observed between the systemic levels of α-1-Ga, C3, and C4 and the number of TRAP-positive cells. CONCLUSIONS: The combination of DOX with LIL as SRP adjuvants was effective both systemically and locally for the treatment of experimental periodontitis in rats.
RESUMO
This study evaluated the influence of Doxycycline (DOX) and Low-Intensity Laser (LIL) (InGaAlP diode laser) as scaling and root planing (SRP) adjuvants in the treatment of periodontitis induced in rats. The rats received periodontal disease induction, and after 7 days, the ligature was removed, and the animals were divided into groups/treatments: NT-receive no treatment; SRP-submitted only to SRP; DOX-submitted to SRP and DOX irrigation; LIL-submitted to SRP and LIL irradiation; and DOX + LIL-submitted to SRP treatments, DOX irrigation and LIL irradiation. The animals were sacrificed at 7, 15 and 30 days, and then, the analyses were performed. A lower concentration of Alpha-glycoprotein acid and Complement 3 was observed in the DOX + LIL group compared to all the other groups in all the periods, and for Complement 4 at 15 and 30 days (P < 0.01). A lower bone loss (BL) was observed in the DOX + LIL group compared to all the other groups in all the periods (P < 0.01). It can be concluded that LIL was effective in the reduction of proteins, and its association with DOX was effective in the reduction of proteins and BL, in the treatment of periodontal induction in rats.
Assuntos
Lasers Semicondutores , Periodontite , Animais , Terapia Combinada , Doxiciclina/farmacologia , Doxiciclina/uso terapêutico , Lasers Semicondutores/uso terapêutico , Periodontite/tratamento farmacológico , Ratos , Ratos Wistar , Aplainamento RadicularRESUMO
To overcome the morbidity of autogenous graft removal and limitations of allogeneic and xenogeneic grafts, a great interest exists in the development of biomaterials of synthetic origin. OBJECTIVE: The aim of this study was to evaluate the biological behavior of a novel bioactive glass (60% SiO2- 36% CaO-4% P2O5) as bone substitute in critical calvaria defects of rats, in comparison to hydroxyapatite. METHODS: Sixty male Wistar rats were divided in three groups, according to the treatment: Control Group (C) - blood clot; Hydroxyapatite (HA) - particulate hydroxyapatite (≤0,5 mm); and Bioactive Glass (BG) - particulate bioactive glass (0.04-1 mm). RESULTS: From the intergroup analysis, it was observed that Group C presented a greater newly formed bone area (NBA) when compared to Groups HA and BG. In addition, Group HA showed higher NBA when compared to Group BG at 30 and 60 days (P < 0.05). Immunohistochemistry revealed that groups HA and BG presented high and moderate osteocalcin immunolabeling respectively. Group HA displayed a greater number of TRAP-positive cells compared to Groups C and BG at 30 and 60 days (p < 0.05). CONCLUSION: From these results, we can conclude that the resorption rate of hydroxyapatite is higher than the novel bioactive glass, which maintained significant higher volume until the last experimental period. Both of the tested biomaterials acted as osteoconductors during bone repair, and their physical characteristics importantly influenced this process.
RESUMO
ABSTRACT Objective: This study verified both the self-perception and oral characteristics of a group of elderly participants of the Open University for the Elderly (UNATI). Methods: The sample consisted of a cross-sectional epidemiological study with elderly subjects (50 years of age or older), who attended the UNATI-UNIFAL/MG program. Data collection was carried out using a semi-structured questionnaire consisting of open- and closed-ended questions regarding oral health, its interference with self-esteem and nutrition, among other features. In addition, an application form based on the proposals by the Oral Health Survey 2010, was used. Univariate and multivariate descriptive analyses were performed. Results: The study sample consisted of 106 subjects (mean age of 62.4 years), of whom 59.4% had attended a dental appointment in the last year for routine and/or aesthetic examinations (38.7%). The clinical conditions showed that only 19.8% of the subjects were completely edentulous, an average DMFT of 26.1, and 37.7% used some kind of complete upper dentures, complete lower dentures, or both. Regarding self-perception of oral conditions, 34.9% considered it a regular perception, however in the applied statistics the presence of pain demonstrated a worse perception which was not correlated with teeth loss, presence of dentures and/or restored teeth. Conclusion: The self-perception of oral conditions is regular and the clinical and odontological characteristics evaluated revealed partial edentulous subjects with high DMFT. By evaluating the odontological aspects, it was observed that the majority of the subjects did not have difficulties to look for a dentist, they attended dental appointments in the last year and the preventive treatment had been the most required.
RESUMO Objetivo: Este estudo verificou a autopercepção, as características bucais e os aspectos odontológicos dos participantes da Universidade Aberta a Terceira Idade (UNATI). Métodos: Refere-se a um estudo epidemiológico transversal com indivíduos a partir de 50 anos de idade que frequentam o programa UNATI-UNIFAL/MG. O instrumento de coleta de dados consistiu em um questionário semiestruturado, composto por perguntas referentes à saúde bucal, interferência da mesma na autoestima e alimentação, entre outros. Além disso, foi utilizada uma ficha clínica baseada nas propostas do Levantamento em Saúde Bucal 2010. Foram realizadas análises descritivas, uni e multivariadas. Resultados: A amostra foi composta por 106 indivíduos, com idade média de 62,4 anos, dentre os quais 59,4% visitaram o cirurgião-dentista no último ano para exames de rotina e/ou estética (38,7%). As condições clínicas evidenciaram que apenas 19,8% dos indivíduos eram desdentados totais, o CPOD médio de 26,1 e 37,7% usava algum tipo de prótese total superior, inferior ou ambas. Quanto a autopercepção das condições bucais, 34,9% se refere regular, contudo, na estatística aplicada a presença de dor determinou uma pior percepção e não esteve correlacionada com a perda de dentes, presença de próteses e/ou dentes restaurados. Conclusão: A autopercepção das condições bucais é regular e as características clínico-odontológicas avaliadas revelaram indivíduos desdentados parciais com elevado CPOD. Ao avaliar os aspectos odontológicos a maioria não apresentou dificuldades ao procurar o cirurgião-dentista, visitaram esse profissional no último ano e o tratamento mais procurado por eles foi o preventivo.
RESUMO
Este estudo objetiva relatar as alterações bucais e o grau de dependência de idosos institucionalizados. Um estudo observacional, transversal, baseado no levantamento da saúde bucal do Projeto Saúde Bucal Brasil (SB, 2010; Brasil, 2011), e Federação Dentária Internacional (FDI, 2009), sobre a classificação de dependência. O índice de ataque de cárie (CPO-D) dos idosos é elevado, edentulismo total expressivo, 52,9% são independentes, sendo que 80% faz a própria higienização bucal. Embora haja um expressivo número de idosos independentes que realizam a própria higiene bucal, os resultados indicam uma saúde bucal precária dos idosos institucionalizados.
Describe oral changes and level of dependency of institutionalized elderly. This cross-sectional observational study according to the rates adopted by the Oral Health Survey (SB 2010) and World Dental Federation on the classification of dependency. DMFT was high (31.0), total edentulism expressive, 52.9% were independente, 80% made their own oral hygiene. Although there is an evident great part of independent individuals who make their own oral hygiene, the results indicate that oral health of institutionalized elderly is very poor.
Este estudio objetiva relatar las alteraciones bucales y el grado de dependencia en ancianos institucionalizados. Un estudio observacional basado en el levantamiento de salud bucal (SB, 2010) y la Federación Dentaria Internacional (CPOD) alto, edentulismo total expresivo, el 52,9% de los ancianos independientes, siendo que el 80,0% hacía su propia higienización bucal. Aunque hay un evidente número de ancianos independientes y que realizan su propia higiene bucal, los resultados indican una salud bucal precaria de los ancianos institucionalizados.
Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Saúde Bucal/estatística & dados numéricos , Estado Funcional , Higiene Bucal , Estudos Transversais , Saúde do Idoso Institucionalizado , Instituição de Longa Permanência para IdososRESUMO
OBJECTIVE: The aim of this study was to evaluate low-level laser therapy (LLLT) as an adjuvant treatment for scaling and root planing (SRP) for the treatment of induced periodontitis in simvastatin-modified rats. MATERIAL AND METHODS: A total of 180 rats were evenly divided into two groups: Veh - receiving oral administration of polyethylene glycol (vehicle); S - receiving oral administration of Simvastatin. Periodontal disease was induced in both groups at the first mandibular molar. After seven days, the ligature was removed and the animals were divided into subgroups according to the following local treatments: NT - no treatment; SRP - scaling and root planing and irrigation with saline solution; and LLLT ¬- SRP and laser irradiation (660 nm; 0.03 W; 4 J). Ten animals in each subgroup/local treatment were euthanized at 7, 15 and 30 days. Samples of gingival tissue were processed to analyze the tissue oxidative damage and radiographic analysis. Levels of oxidative stress were analyzed by the expressions of Tripeptideglutathione (TG), Malondialdehyde (MDA) and Carbonylated Proteins (CP). RESULTS: The animals in S group had higher levels of TG and lower levels of MDA and CP compared with Veh group (p<0.05). Radiographically, in the intragroup analysis Veh and S, LLLT showed lower bone loss (BL) compared with NT and SRP, in all experimental periods (p<0.01). In addition, a lower BL was observed for the animals of Veh group treated with LLLT compared with treatment SRP in the S group, in all experimental periods. CONCLUSION: Within the limits of this study, we can conclude that LLLT was effective as adjuvant treatment for SRP protecting against the occurrence of oxidative tissue damages as well as for reducing alveolar bone loss in experimentally induced periodontitis simvastatin-modified rats.
Assuntos
Raspagem Dentária/métodos , Inibidores de Hidroximetilglutaril-CoA Redutases/farmacologia , Lasers Semicondutores/uso terapêutico , Terapia com Luz de Baixa Intensidade/métodos , Periodontite/terapia , Sinvastatina/farmacologia , Animais , Gengiva/química , Gengiva/efeitos dos fármacos , Glutationa/análise , Masculino , Malondialdeído/análise , Mandíbula/diagnóstico por imagem , Periodontite/diagnóstico por imagem , Carbonilação Proteica , Radioterapia Adjuvante , Distribuição Aleatória , Ratos Wistar , Valores de Referência , Reprodutibilidade dos Testes , Fatores de Tempo , Resultado do TratamentoRESUMO
Abstract Low intensity laser can be used as a promising alternative in the treatment of periodontal disease. Objective The aim of this study was to evaluate low-level laser therapy (LLLT) as an adjuvant treatment for scaling and root planing (SRP) for the treatment of induced periodontitis in simvastatin-modified rats. Material and Methods A total of 180 rats were evenly divided into two groups: Veh - receiving oral administration of polyethylene glycol (vehicle); S - receiving oral administration of Simvastatin. Periodontal disease was induced in both groups at the first mandibular molar. After seven days, the ligature was removed and the animals were divided into subgroups according to the following local treatments: NT - no treatment; SRP - scaling and root planing and irrigation with saline solution; and LLLT ¬- SRP and laser irradiation (660 nm; 0.03 W; 4 J). Ten animals in each subgroup/local treatment were euthanized at 7, 15 and 30 days. Samples of gingival tissue were processed to analyze the tissue oxidative damage and radiographic analysis. Levels of oxidative stress were analyzed by the expressions of Tripeptideglutathione (TG), Malondialdehyde (MDA) and Carbonylated Proteins (CP). Results The animals in S group had higher levels of TG and lower levels of MDA and CP compared with Veh group (p<0.05). Radiographically, in the intragroup analysis Veh and S, LLLT showed lower bone loss (BL) compared with NT and SRP, in all experimental periods (p<0.01). In addition, a lower BL was observed for the animals of Veh group treated with LLLT compared with treatment SRP in the S group, in all experimental periods. Conclusion Within the limits of this study, we can conclude that LLLT was effective as adjuvant treatment for SRP protecting against the occurrence of oxidative tissue damages as well as for reducing alveolar bone loss in experimentally induced periodontitis simvastatin-modified rats.
Assuntos
Animais , Masculino , Periodontite/terapia , Raspagem Dentária/métodos , Inibidores de Hidroximetilglutaril-CoA Redutases/farmacologia , Sinvastatina/farmacologia , Terapia com Luz de Baixa Intensidade/métodos , Lasers Semicondutores/uso terapêutico , Periodontite/diagnóstico por imagem , Valores de Referência , Fatores de Tempo , Distribuição Aleatória , Reprodutibilidade dos Testes , Resultado do Tratamento , Ratos Wistar , Radioterapia Adjuvante , Carbonilação Proteica , Gengiva/efeitos dos fármacos , Gengiva/química , Glutationa/análise , Malondialdeído/análise , Mandíbula/diagnóstico por imagemRESUMO
OBJECTIVE: The objective of this study was to evaluate the local effects of statins as adjuvants for treatment by scaling and root planing (SRP) of periodontal disease induced in rats. MATERIAL AND METHODS: Ninety rats were used in the present experiment. Periodontal disease was induced in all animals using a cotton thread placed in the left first mandibular molar. After 7 days of induction, the bandage was removed and the animals were divided into three groups: 1) NT group (n=30), no treatment; 2) SRP group (n=30): SRP and irrigation with control gel; 3) S group (n=30) - SRP and irrigation with Simvastatin. Ten animals from each group were euthanized at 7, 15 and 30 days after treatment. Gingival biopsy specimens were processed to analyze the expression of matrix metalloproteinase 8 (MMP-8). The mandibles were removed and submitted to radiographic and laboratory processing for histometric analysis. RESULTS: The S group showed a significantly lower expression of MMP-8 compared to NT and SRP groups in all experimental periods. In the radiographic and histometric analyses between the groups, S group showed a significantly lower bone loss (BL) compared to NT and SRP groups in all experimental periods. CONCLUSIONS: Within the limits of this study, it can be concluded that locally applied statin was effective as an adjuvant treatment for SRP in rats with induced periodontal disease.
Assuntos
Conservadores da Densidade Óssea/farmacologia , Periodontite/tratamento farmacológico , Aplainamento Radicular/métodos , Sinvastatina/farmacologia , Animais , Biópsia , Quimioterapia Adjuvante , Gengiva/efeitos dos fármacos , Gengiva/patologia , Masculino , Mandíbula/diagnóstico por imagem , Mandíbula/patologia , Metaloproteinase 8 da Matriz/análise , Periodontite/patologia , Ratos Wistar , Reprodutibilidade dos Testes , Fatores de TempoRESUMO
Abstract Objective The objective of this study was to evaluate the local effects of statins as adjuvants for treatment by scaling and root planing (SRP) of periodontal disease induced in rats. Material and Methods Ninety rats were used in the present experiment. Periodontal disease was induced in all animals using a cotton thread placed in the left first mandibular molar. After 7 days of induction, the bandage was removed and the animals were divided into three groups: 1) NT group (n=30), no treatment; 2) SRP group (n=30): SRP and irrigation with control gel; 3) S group (n=30) - SRP and irrigation with Simvastatin. Ten animals from each group were euthanized at 7, 15 and 30 days after treatment. Gingival biopsy specimens were processed to analyze the expression of matrix metalloproteinase 8 (MMP-8). The mandibles were removed and submitted to radiographic and laboratory processing for histometric analysis. Results The S group showed a significantly lower expression of MMP-8 compared to NT and SRP groups in all experimental periods. In the radiographic and histometric analyses between the groups, S group showed a significantly lower bone loss (BL) compared to NT and SRP groups in all experimental periods. Conclusions Within the limits of this study, it can be concluded that locally applied statin was effective as an adjuvant treatment for SRP in rats with induced periodontal disease.
Assuntos
Animais , Masculino , Periodontite/tratamento farmacológico , Aplainamento Radicular/métodos , Sinvastatina/farmacologia , Conservadores da Densidade Óssea/farmacologia , Periodontite/patologia , Fatores de Tempo , Biópsia , Reprodutibilidade dos Testes , Quimioterapia Adjuvante , Ratos Wistar , Metaloproteinase 8 da Matriz/análise , Gengiva/efeitos dos fármacos , Gengiva/patologia , Mandíbula/patologia , Mandíbula/diagnóstico por imagemRESUMO
O estudo avaliou a Sinvastatina no tratamento da doença periodontal (DP) em ratos. Trinta e seis animais foram divididos em Grupo Controle (C) que receberam oralmente soro fisiológico e Sinvastatina (S) que receberam oralmente Sinvastatina. Após 24 horas, a DP foi induzida utilizando-se um fio de algodão na região dento-gengival dos primeiros molares inferiores esquerdos. Após 7 dias, a ligadura foi removida e os animais receberam raspagem e alisamento radicular (RAR) e irrigação com soro fisiológico. Os animais foram eutanasiados aos 7, 15 e 30 dias. Radiograficamente, o tratamento com RAR mostrou uma menor perda óssea (PO) no Grupo S comparado ao C em todos os períodos. Concluiu-se que a Sinvastatina associada à RAR foi efetiva na redução da PO em ratos.
The study evaluated simvastatin in the treatment of periodontal disease (PD) in rats. 36 animals were divided into control group (C) receiving oral saline and Simvastatin (S) who received oral simvastatin. After 24 hours the PD was induced using a cotton yarn in the dento-gingival area of the first left molar. After 7 days the ligature was removed and animals received scaling and root planing (SRP) and irrigation with saline. The animals were sacrificed at 7, 15 and 30 days. Radiographically treatment with SRP showed less bone loss (BL) in the S group compared to C in all periods. It was concluded that SRP associated with simvastatin was effective in reducing the BL in rats.a
RESUMO
Objective: To report the self-perception of substance-abusing individuals who were in a recovery process regarding sociodemographic conditions and general and oral health. Methods: Descriptive cross-sectional study conducted in a recovery center for drug addiction in Alfenas, Minas Gerais, Brazil, in 2015, with 39 men aged over 18 years old. Data were collected using a semi-structured questionnaire that addressed: socioeconomic status, selfperception of general and oral health, access to dental care, relationship with the dentist, and other issues. In order to assess the self-perception of oral health, the variable was dichotomized into "satisfactory" and "unsatisfactory", which refer to what the individual acknowledges as a good or poor condition of oral health, using Fisher's exact test with 5% significance level. Results: Most frequent diseases were depression, 35.90% (n=14), insomnia, 35.9%, (n=14) and recurring headache (23.1%; n=9); however, 61.50% (n=24) of the participants reported not getting sick easily, which contrasts with their self-perception. Regarding oral health, only 30.50% (n=12) of the participants reported brushing their teeth three times a day; 53.80% (n=21) had dentinal hypersensitivity; 41.00% (n=16) had dry mouth and bad breath; 30.80% (n=12) claimed to have bruxism and reported having one or more loose teeth; 28.20% (n=11) reported clenching the teeth in an exaggerated way, and 33.30% (n=13) reported feeling tooth pain. Conclusion: The self-perception of individuals under 30 years old, single, white or mulattos regarding their general health was contradictory, as they rated it as good but have reported depression, insomnia and weight loss; additionally, oral health was considered poor with unsatisfactory conditions, which highlights the harmful effects of substance abuse.
Objetivos: Relatar a autopercepção de indivíduos drogaditos que se encontravam em estágio recuperatório, quanto às condições sociodemográficas, de saúde geral e bucal. Métodos: Estudo descritivo e transversal realizado em 2015 em um centro de triagem de recuperação de dependentes químicos, em Alfenas, MG, Brasil, com 39 internos do sexo masculino e acima de 18 anos. Por meio de um questionário semi-estruturado, investigaram-se temas referentes à condição socioeconômica, percepção dos internos em relação à própria saúde geral e bucal, acesso ao tratamento odontológico, relacionamento com o cirurgião-dentista, entre outros. A variável autopercepção em saúde bucal foi dicotomizada em "satisfatória" e "insatisfatória" para aplicação do teste Exato de Fisher, com nível de significância de 5%. Resultados: As doenças mais frequentes foram depressão, 35,90% (n=14), insônia, 35,9%, (n=14) e dor de cabeça recorrente (23,1%; n=9), apesar de 61,50% (n=24) dos internos afirmarem não ficar doentes, indicando autopercepção conflitante. Ao serem questionados sobre a frequência de escovação diária, apenas 30,50% (n=12) mencionaram três vezes ao dia, 53,80% (n=21) com sensibilidade dentinária; 41,00% (n=16) com sensação de boca seca e mal hálito; 30,80% (n=12) bruxismo, 28,20% (n=11) apertamento dental e 33,30% (n=13) dor em algum dente. Conclusão: A autopercepção dos internos analisados com menos de 30 anos, solteiros, brancos ou mulatos, quanto ao seu estado geral de saúde era contraditória, já que classificaram como boa, mas relataram depressão, insônia e perda de peso; e saúde bucal foi considerada ruim com condições insatisfatórias, que destacam os efeitos nocivos do uso de drogas.
Objetivo: Relatar la auto percepción de individuos drogadictos que estaban en proceso de recuperación, respecto las condiciones socio-demográficas y la salud general y bucal. Métodos: Estudio transversal y descriptivo realizado en un centro de recuperación para drogadicción en Alfenas, Minas Gerais, Brasil, en 2015, com 39 hombres con más de 18 años. Los datos fueron recogidos a través de un cuestionario semiestructurado que investigaba la posición socioeconómica, la auto percepción de la salud general y bucal, El acceso al cuidado dental, la relación con el dentista y otros temas. Para evaluar la auto percepción de la salud bucal la variable fue dividida en "satisfactoria" y "no satisfactoria" la cual refiere a los conocimientos del individuo sobre la buena o mala condición de salud bucal utilizando la prueba de Exacto de Fisher con El 5% de nivel de significancia. Resultados: Las enfermedades más frecuentes fueron la depresión con el 35,90% (n=14), el insomnio con el 35,9%, (n=14) y dolor de cabeza recurrente (23,1%; n=9); sin embargo, el 61,50% (n=24) de los participantes relataron no enfermarse con facilidad lo que contrasta con su auto percepción. Respecto a la salud bucal, solamente el 30,50% (n=12) de los participantes relataron cepillar los dientes tres veces al día; El 53,80% (n=21) tuvieron hipersensibilidad dental; el 41,00% (n=16) tuvieron la sensación de boca seca y mal aliento; El 30,80% (n=12) reclamaron de bruxismo y relataron tener uno o más dientes perdidos; el 28,20% (n=11) relataron apretar los dientes de manera exagerada y el 33,30% (n=13) relataron tener dolor de diente. Conclusión: La auto percepción de los individuos - por abajo de los 30 años, solteros, blancos o mulatos - respecto su salud general fue contradictoria ya que clasificaron como buena aunque reportaron la depresión, el insomnio y La pérdida de peso; además, la salud bucal fue considerada pobre con condiciones no satisfactorias, las cuales resalta los efectos nocivos de la substancia abusiva.
Assuntos
Qualidade de Vida , Saúde Bucal , Usuários de DrogasRESUMO
BACKGROUND: This study assesses the effects of topical sodium alendronate (SA) as an adjuvant to the mechanical treatment of ligature-induced periodontitis in rats. METHODS: Ninety animals were subjected to the induction of periodontitis via the installation of a ligature around the mandibular left first molar. After 7 days, the ligature was removed, and the animals were distributed into the following groups: 1) NT group (n = 30), no treatment; 2) SRP group (n = 30), scaling and root planing (SRP) and local irrigation with physiologic saline solution; and 3) SRP/SA group (n = 30), SRP and local irrigation with SA (10(-5) M). Ten animals from each group were euthanized at 7, 15, and 30 days after treatment. Histologic and histometric analyses were performed in the furcation region. The percentage of bone in the furcation (PBF) was measured. Immunohistochemical analyses for detecting the receptor activator of nuclear factor-κB ligand (RANKL), osteoprotegerin (OPG), tartrate-resistant acid phosphatase (TRAP), and activated caspase-3 were performed at the furcation region. RESULTS: Compared with the other groups, the SRP/SA group showed less local inflammation and better tissue reparation during the entire experiment. There was more PBF in the SRP/SA group than in the other groups at days 7 and 15. Stronger OPG immunolabeling and weaker RANKL immunolabeling were observed in the SRP/SA group at 15 and 30 days. There were fewer TRAP-positive cells in the SRP/SA group than in the NT group at all of the time points. There was no difference in the number of activated caspase-3-positive osteocytes among groups and time points. CONCLUSION: It can be concluded that topical use of SA as an adjuvant to SRP is effective in the treatment of experimental periodontitis.
Assuntos
Alendronato/uso terapêutico , Conservadores da Densidade Óssea/uso terapêutico , Raspagem Dentária/métodos , Periodontite/tratamento farmacológico , Aplainamento Radicular/métodos , Alendronato/administração & dosagem , Processo Alveolar/efeitos dos fármacos , Processo Alveolar/patologia , Animais , Apoptose/efeitos dos fármacos , Conservadores da Densidade Óssea/administração & dosagem , Caspase 3/análise , Terapia Combinada , Osteoclastos/efeitos dos fármacos , Osteócitos/efeitos dos fármacos , Osteoprotegerina/análise , Periodontite/patologia , Periodontite/terapia , Ligante RANK/análise , Ratos , Ratos Wistar , Fosfatase Ácida Resistente a Tartarato/análise , Irrigação Terapêutica/métodos , Fatores de TempoRESUMO
Introduction: The dentin hypersensitivity associated with gingival recession is an occurrence of high prevalence in the clinical routine of dentists. Coverage of exposed root surfaces represents a challenge for periodontal treatment. Objective: The purpose of the present study is to describe an approach for adjacent gingival recession treatment using a combination of two surgical techniques: the subepithelial connective tissue graft (SCTG) with a laterally positioned double flap. Case report: This surgical treatment was conducted in a 45-yearold female patient who complained of sensitivity when brushing the lower right teeth. Clinical and radiographic examinations showed gingival recessions (Miller Class III) with traumatic origin promoted for tooth brushing and the presence of thin periodontium in the region. In addition, interproximal bone loss was noted on vestibular face of the right mandibular second premolar and mesial root of the right mandibular first molar. At 12 postoperative months, it was observed that the association of the two surgical techniques promoted an almost complete coverage of the gingival recessions, an increased keratinized gingival band and the elimination of initial dentin hypersensitivity. Conclusion: The appropriate choice of techniques and patient compliance to the periodontal support therapy led to treatment success and periodontal health maintenance in the region during the whole follow-up period.
RESUMO
The purpose of this study was to analyze histologically the effect of low-level laser therapy (LLLT) in combination with bisphosphonate on bone healing in surgically created critical size defects (CSD) in rat calvaria. One hundred Wistar female rats sham operated (sham) and ovariectomized (Ovx) were maintained untreated for 1 month to allow for the development of osteopenia in the Ovx animals. A CSD was made in the calvarium of each rat, and the animals were divided into five groups according to following treatments: (1) sham rats (control), (2) Ovx rats, (3) Ovx rats treated with LLLT, (4) Ovx rats treated with bisphosphonate, and (5) Ovx rats treated with bisphosphonate and LLLT. Groups 4 and 5 were irrigated with 1 ml of bisphosphonate, and groups 3 and 5 were submitted to LLLT (GaAlAs), 660 nm, 24 J, and 0.4285 W/cm(2) on the CSD. Ten animals of each treatment were killed at 30 and 60 days. Histomorphometric assessments, using image analysis software, and histological analyses were performed. No defect was completely regenerated with the bone. Histometrically, it can be observed that groups 3 (37.49 ± 1.94%, 43.11 ± 2.39%) and 5 (35.05 ± 1.57%, 41.07 ± 1.89%) showed a significant bone neoformation when compared to groups 1 (16.81 ± 1.57%, 27.54 ± 1.49%), 2 (11.68 ± 0.98%, 22.51 ± 1.05%), and 4 (14.62 ± 1.70%, 25.67 ± 1.41%) in all experimental periods (P < 0.05). It was possible to conclude that the LLLT associated or not with bisphosphonate treatment was effective for stimulating bone formation in CSD in the calvaria of rats submitted to ovariectomy.
Assuntos
Regeneração Óssea/efeitos dos fármacos , Regeneração Óssea/efeitos da radiação , Difosfonatos/farmacologia , Terapia com Luz de Baixa Intensidade/métodos , Crânio/efeitos da radiação , Animais , Conservadores da Densidade Óssea/farmacologia , Doenças Ósseas Metabólicas/cirurgia , Interpretação Estatística de Dados , Feminino , Processamento de Imagem Assistida por Computador , Ovariectomia , Ratos , Ratos Wistar , Crânio/efeitos dos fármacos , Crânio/patologia , Crânio/cirurgiaRESUMO
Low-level laser (LLL) has been used on peri-implant tissues for accelerating bone formation. However, the effect of one session of LLL in the strength of bone-implant interface during early healing process remains unclear. The present study aims to evaluate the removal torque of titanium implants irradiated with LLL during surgical preparation of implant bed, in comparison to non-irradiation. Sixty-four Wistar rats were used. Half of the animals were included in LLL group, while the other half remained as control. All animals had the tibia prepared with a 2 mm drill, and a titanium implant (2.2 × 4 mm) was inserted. Animals from LLL group were irradiated with laser (gallium aluminum arsenide), with a wavelength of 808 nm, a measured power output of 50 mW, to emit radiation in collimated beams (0.4 cm(2)), for 1 min and 23 s, and an energy density of 11 J/cm(2). Two applications (22 J/cm(2)) were performed immediately after bed preparation for implant installation. Flaps were sutured, and animals from both groups were sacrificed 7, 15, 30, and 45 days after implant installation, when load necessary for removing implant from bone was evaluated by using a torquimeter. In both groups, torque values tended to increase overtime; and at 30 and 45 days periods, values were statistically higher for LLL group in comparison to control (ANOVA test, p < 0.0001). Thus, it could be suggested that a single session of irradiation with LLL was beneficial to improve bone-implant interface strength, contributing to the osseointegration process.