RESUMO
Visceral leishmaniasis (VL) is an endemic parasitic disease frequently found in Northeast Brazil and may cause acute kidney injury (AKI) and glomerulonephritis. After appropriate treatment, renal function recovery may occur. We describe the rare case of a patient with VL, who developed severe AKI requiring dialysis and was subsequently diagnosed with Chagas disease coinfection. After specific treatment for VL, there was partial recovery of the renal function, followed by the onset of Chagas disease cardiomyopathy.
Assuntos
Injúria Renal Aguda/parasitologia , Cardiomiopatia Chagásica/complicações , Glomerulonefrite/parasitologia , Leishmaniose Visceral/complicações , Injúria Renal Aguda/diagnóstico , Injúria Renal Aguda/patologia , Cardiomiopatia Chagásica/diagnóstico , Cardiomiopatia Chagásica/patologia , Coinfecção , Glomerulonefrite/diagnóstico , Glomerulonefrite/patologia , Humanos , Leishmaniose Visceral/diagnóstico , Leishmaniose Visceral/patologia , Masculino , Pessoa de Meia-IdadeRESUMO
INTRODUCTION: This study aimed to describe the clinical spectrum of dengue in children and adolescents from a hyperendemic region who were admitted for hospitalization. METHODS: A retrospective study was conducted on patients diagnosed with dengue infection upon admission to a reference center in Fortaleza, Brazil. RESULTS: Of the 84 patients included, 42 underwent confirmatory testing. The main symptoms were fever, abdominal pain and vomiting. The median level of serum aspartate aminotransferase was 143.5±128mg/dL. CONCLUSIONS: A peculiar clinical profile was evident among children and adolescents with dengue infection in a reference center in northeast Brazil, including gastrointestinal symptoms and liver involvement.