RESUMO
Introducción: El incremento del número de personas poseedoras de un estoma, trae consigo la necesidad de contar con personal capacitado para proporcionarle los elementos necesarios para su reintegración a la vida social, familiar y laboral. Objetivo: Analizar el efecto que tiene la intervención educativa de enfermería para la rehabilitación de personas con una ostomia. Metodología: Se trata de un estudio de tipo cuasi-experimental, la muestra se constituyó de 110 personas ostomizadas de cuatro hospitales a las que se les aplicó un instrumento que fue validado por expertos en el área. Para el análisis de datos se utilizó estadística descriptiva e inferencial por medio de la X2. Resultados: En los resultados se observa diferencia estadísticamente significativa entre la intervención educativa y la rehabilitación laboral (p=0.000), también se observo diferencia estadísticamente significativa entre la intervención educativa y la rehabilitación social y familiar (p=0.000). Discusión: Coincidiendo con Montovani en donde afirma que la falta de información, educación y comunicación son la causa para que el paciente no pueda participar activamente en su autocuidado. De acuerdo con Boccardo se establece que la mayoría de los pacientes ostomizados no retornan totalmente al trabajo pero si parcialmentea sus actividades siendo ésta la parte más difícil de superar. Conclusiones: Se sustenta que la intervención educativa en personas ostomizadas planificada,estandarizada y evaluada, es fundamental para lograr su rehabilitación educativa, laboral, social y familiar.
Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Estomia , ReabilitaçãoRESUMO
The present study analyzed several characters of the red seaweed Gymnogongrus torulosus, such as cellular structure of the thallus, cuticle, pit plug and cell wall ultrastructure, and morphology of some organelles like plastids, Golgi bodies and mitochondria. Also, anomalous chloroplasts with thylakoid disorganization were found in medullary cells. The significance of this thylakoid disposition is still unclear. This is one of the first studies focused on the fine structure of a red alga recorded in Argentina.
Assuntos
Alga Marinha/ultraestrutura , Rodófitas/ultraestrutura , Organelas/ultraestrutura , Alga Marinha/fisiologia , Rodófitas/fisiologia , Complexo de Golgi/fisiologia , Complexo de Golgi/ultraestrutura , Cloroplastos/fisiologia , Cloroplastos/ultraestrutura , Microscopia Eletrônica , Mitocôndrias/fisiologia , Mitocôndrias/ultraestrutura , Organelas/fisiologia , Parede Celular/fisiologia , Parede Celular/ultraestrutura , Plastídeos/fisiologia , Plastídeos/ultraestrutura , Tilacoides/fisiologia , Tilacoides/ultraestruturaRESUMO
The present study analyzed several characters of the red seaweed Gymnogongrus torulosus, such as cellular structure of the thallus, cuticle, pit plug and cell wall ultrastructure, and morphology of some organelles like plastids, Golgi bodies and mitochondria. Also, anomalous chloroplasts with thylakoid disorganization were found in medullary cells. The significance of this thylakoid disposition is still unclear. This is one of the first studies focused on the fine structure of a red alga recorded in Argentina. (AU)
Assuntos
RESEARCH SUPPORT, NON-U.S. GOVT , Rodófitas/ultraestrutura , Organelas/ultraestrutura , Alga Marinha/ultraestrutura , Rodófitas/fisiologia , Parede Celular/fisiologia , Parede Celular/ultraestrutura , Cloroplastos/fisiologia , Cloroplastos/ultraestrutura , Complexo de Golgi/fisiologia , Complexo de Golgi/ultraestrutura , Microscopia Eletrônica , Mitocôndrias/fisiologia , Mitocôndrias/ultraestrutura , Organelas/fisiologia , Plastídeos/fisiologia , Plastídeos/ultraestrutura , Alga Marinha/fisiologia , Tilacoides/fisiologia , Tilacoides/ultraestruturaRESUMO
A novel series of DL-galactan hybrids extracted from the red seaweed Gymnogongrus torulosus, was evaluated for its in vitro antiviral properties against herpes simplex virus type 2 (HSV-2) and dengue virus 2 (DEN-2). These compounds were very active against both viruses with inhibitory concentration 50% (IC50) values in the range 0.6-16 microg/ml for HSV-2 and 0.19-1.7 microg/ml for DEN-2, respectively, as determined in a virus plaque reduction assay in Vero cells. The DL-galactans lacked of cytotoxic effects, on stationary as well as on actively dividing cells, and anticoagulant properties. Some of the compounds showed a variable level of direct inactivating effect on both virions, with virucidal concentration 50% values exceeding the IC50s obtained by plaque reduction assay. Full inhibitory activity was achieved when the galactans were present during virus adsorption period, suggesting that the mode of action of these compounds is an interference in the binding of the surface envelope glycoprotein with the cell receptor.
Assuntos
Antivirais/farmacologia , Vírus da Dengue/efeitos dos fármacos , Galactanos/farmacologia , Herpesvirus Humano 2/efeitos dos fármacos , Alga Marinha/química , Adsorção/efeitos dos fármacos , Animais , Antivirais/isolamento & purificação , Antivirais/toxicidade , Chlorocebus aethiops , Galactanos/isolamento & purificação , Galactanos/toxicidade , Concentração Inibidora 50 , Simplexvirus/efeitos dos fármacos , Tempo de Trombina , Células Vero , Proteínas do Envelope Viral/antagonistas & inibidoresRESUMO
Seaweeds from the genus Gymnogongrus are known to be carrageenophytes; nevertheless, fractionation techniques used previously for the separation of gel-forming and 'soluble' carrageenans, applied to the galactans of Gymnogongrus torulosus together with enantiomeric analysis of the sugar components and (when possible) of the structural units, suggested that the system of galactans biosynthesized by the seaweed was formed by DL-galactan hybrids having major amounts of carrageenan-type or agaran-type chains, with minor quantities of agarans with unusual structural details.
Assuntos
Ágar/química , Galactanos/química , Rodófitas/química , Alga Marinha/química , Ágar/isolamento & purificação , Configuração de Carboidratos , Carragenina/química , Carragenina/isolamento & purificação , Cromatografia em Gel , Dissacarídeos/química , Galactanos/isolamento & purificação , Metilação , Monossacarídeos/análise , Ressonância Magnética Nuclear Biomolecular , EstereoisomerismoRESUMO
The room-temperature-extracted fraction from the red seaweed Kappaphycus alvarezii consists mainly of low-molecular-weight carrageenans, with structural dispersion around a basic kappa-pattern. This dispersion results from: (a) low percentages of 3,6-anhydrogalactose and the presence of precursor units; (b) important quantities of 6-O-methyl beta-D-galactose (4-sulfate) residues; (c) significant amounts of iota-repeating structure, and (d) small amounts of non-sulfated and disulfated beta-D-galactose residues. Significant quantities of alpha-L-galactose units suggest the presence of agaroids, as it has been reported in several other carrageenophytes.