RESUMO
We report a clinic-endoscopical study about 365 patients, both of sex, between 26-95 years old, with colonoscopic diagnosis of colorectal cancer. Results showed that 61,92% were men and 38,08% women; in 92,60% the disease ocurred over 40 years old. 13,42% had malignant personal history -colorectal cancer, uterus and breast cancer, and others-; 13,97% had bening personal history-colorectal adenoma, cholecystectomy, and others-; Abdomina pain, change in intestinal habits, and bleeding were the moist frequent symptoms, with differences depending of the tumors localization in the colon or rectum. 62,57% of patients had anemia under 10g% of hernoglobin; in 85,23% the fecal occult blood test was positive. On 199 patients, the simple barium enema diagnosed the tumor in 66,33% only; but in the same group, colonoscopy diagnosed the cancer in 96,49% at first examination. In all patients, colonoscopywas excellent for diagnosis of the principal lesion, and for the identification of synchronous neoplasia. On 365 patients, colonoscopy diagnosed the cancer in 98,08% at first examination. The localization of tumors was: 57,63% in left colon (49,47% in rectum and sigmoid colon); 34,21% in the right colon; and 8,16% in transverse. Pathology showed that adenocarcinoma was the most frequent tumor 95,23%; 1,06% mucoid carcinoma; 1,06% epidermoid carcinoma; and 2,65% lymphorna. In 32,05% of cases there were synchronous lesions; 3,01% had other cancer, and 54 patients had 112 polyps (62,50% adenomatous polyp, 6,25% adenoma with non invasive or invasive adenocarcinoma, and 31,25% hiperplastic polyp. Authors emphasize the value of the detection and early diagnosis to decrese the colorectal cancer mortality.
Assuntos
Colonoscopia , Neoplasias Colorretais/epidemiologia , Dor Abdominal/etiologia , Adenocarcinoma/diagnóstico , Adenocarcinoma/epidemiologia , Adenocarcinoma/patologia , Adenocarcinoma Mucinoso/diagnóstico , Adenocarcinoma Mucinoso/epidemiologia , Adenocarcinoma Mucinoso/patologia , Adenoma/diagnóstico , Adenoma/epidemiologia , Adenoma/patologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Bário , Carcinoma de Células Escamosas/diagnóstico , Carcinoma de Células Escamosas/epidemiologia , Carcinoma de Células Escamosas/patologia , Doenças do Colo/diagnóstico , Doenças do Colo/epidemiologia , Doenças do Colo/patologia , Pólipos do Colo/diagnóstico , Pólipos do Colo/epidemiologia , Pólipos do Colo/patologia , Colonoscopia/estatística & dados numéricos , Neoplasias Colorretais/diagnóstico , Neoplasias Colorretais/patologia , Doença de Crohn/diagnóstico , Doença de Crohn/epidemiologia , Doença de Crohn/patologia , Divertículo do Colo/diagnóstico , Divertículo do Colo/epidemiologia , Divertículo do Colo/patologia , Humanos , Linfoma não Hodgkin/diagnóstico , Linfoma não Hodgkin/epidemiologia , Linfoma não Hodgkin/patologia , Pessoa de Meia-Idade , Neoplasias Primárias Múltiplas/diagnóstico , Neoplasias Primárias Múltiplas/epidemiologia , Neoplasias Primárias Múltiplas/patologia , Sangue Oculto , Peru/epidemiologia , Estudos RetrospectivosRESUMO
318 adenomatous polyps were removed by colonoscopic polypectomy, from two hundred patients, between 25 to 88 years old; 60.50% men, and 39.50% women. 86.50% of patients were older than 50 years old. In 64.50% of patients the adenomatous polyp was single, and 35.50% had "multiple adenoma"; the lesions distribution was 72.64% in the rectum-sigmoid colon. The grade of dysplasia was severe in adenomas over 20mm, and in those of villous type. The malignant percentage was: 1.61% in the adenomatous polyp under 10mm in diameter, 8.49% in those of 10mm to 19mm, and 30.68% in the adenomas of 20mm or more. The adenocarcinomatous focus increased from 1.69% in the adenomas under 10mm to 58.33% in those of 40mm or more in diameter. The relationship between type of adenomatous polyp and his adenocarcinoma incidence was 7.66% in tubular type, 22.22% in tubular-villous, and 26.32% in villous type. The carcinoma incidence in all of the adenomas of this series was 11.95%.
Assuntos
Adenoma/cirurgia , Neoplasias Colorretais/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Colonoscopia , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
598 colorectal polyps were removed by therapeutic colonoscopy from 377 patients, of both sexes, between 1 and 88 years old, most of them with lower digestive symptoms. The polyps were unique in 67.37% and multiple in 32.63% of patients, and mostly located in rectum and sigmoid colon; 42.14% were pedunculated, 33.95% sessile++/sub-pedunculated, and 23.91% sessile in shape. In 51% the size was over 10 mm in diameter. Histologically, 68.68% were of epithelial neoplastic type: 60.91% adenoma; 6.42% adenoma with adenocarcinoma, and 1.35% polypoid carcinoma. 30.64 were epithelial non-neoplastic type: 20.32% hyperplastic polyp, and 0.51% hyperplastic polyp with tubular adenoma. Two patients (0.53%) had lower digestive hemorrhage immediately after the polypectomy. The complications were controlled with conservative measures without blood transfusion.
Assuntos
Pólipos do Colo/cirurgia , Colonoscopia , Pólipos/cirurgia , Neoplasias Retais/cirurgia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Pólipos do Colo/complicações , Pólipos do Colo/diagnóstico , Colonoscópios , Colonoscopia/estatística & dados numéricos , Feminino , Seguimentos , Hemorragia Gastrointestinal/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Pólipos/complicações , Pólipos/diagnóstico , Complicações Pós-Operatórias/epidemiologia , Neoplasias Retais/complicações , Neoplasias Retais/diagnósticoRESUMO
A multicenter, open study was designed to evaluate the efficacy and tolerability of a novel and potent H2 receptor antagonist, Famotidine, in the treatment of duodenal ulcer. Thirty-four patients with endoscopically proven active duodenal ulcer were treated with Famotidine, 40 mg, one tablet, at bedtime, for six weeks. Follow-up endoscopic exams were done every two weeks until ulcer healing was obtained. One patient was excluded from further analysis as he failed to follow the protocol. Healing rates achieved were 48.5%, 91% and 97% by the second, fourth and sixth week of treatment respectively. After 72 hours 52% of the patients were asymptomatic and 79% at the end of the first week of treatment. Famotidine was well tolerated, no clinical neither laboratory adverse events were observed during the study. Famotidine, a novel H2 receptor antagonist appears to be effective and well tolerated in the treatment of most patients with duodenal ulcer.
Assuntos
Úlcera Duodenal/tratamento farmacológico , Famotidina/uso terapêutico , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , PeruRESUMO
Between June 1959 and June 1975 at the Central Hospital No. 2 of the Social Security of Peru, 186 patients were found with elevated stomach lesions. From these the authors selected 92 with 94 lesions studied histologically that corresponded to polyps, 11 pseudo-polyps, 3 polyposis, 1 pseudopolyposis, 10 submucous tumors, and 8 malignant lesions. The rest corresponded to gastritis, atypias or normal mucosa.
Assuntos
Gastropatias , Neoplasias Gástricas , Feminino , Tecnologia de Fibra Óptica , Gastroscopia , Humanos , Masculino , Gastropatias/diagnóstico , Neoplasias Gástricas/diagnósticoRESUMO
Fiber colonoscopy permitted us to elucidate radiological suspicions of lesions of the colon established after repeated studies. It served to complement the radiological findings and to detect previously undiagnosed lesions and even to avoid possibly unnecessary surgical explorations when it negated the radiological diagnosis of malignant lesion. In this series, in which there were insufficient studies, no complications were registered.
Assuntos
Doenças do Colo/diagnóstico por imagem , Adulto , Idoso , Feminino , Tecnologia de Fibra Óptica , Humanos , Masculino , Pessoa de Meia-Idade , Radiografia , SigmoidoscopiaRESUMO
In our hospital the incidence of upper digestive hemorhage [UDH] is greater after the 4th decade of age and predominantes in the male sex. The patients' clinical data was important in the diagnosis of the lesion. In 63% of our cases a close relation was found between the previous intake of substances considered ulcerogenous and the hemorrhagic episode, as well as the presence of stress situations. In our experiences the causes of UDH in order of their frequency are: 1. Acute lesions of the gastric mucosa. 2. Duodenal ulcer. 3. Gastric ulcer. 4. Stomal ulcer. 5. Bleeding esophagitis. 6. Others. The digestive hemorrhages of undetermined caused corresponded to 2,33% of the cases. The early diagnosis of UDH by means of emergency endoscope was of great value in the therapeutic handling of patients.