RESUMO
JUSTIFICATIVA: Pacientes com artrite reumatoide (AR) têm manifestações extra-articulares em até 50 por cento dos casos OBJETIVO: Estudar a prevalência das alterações pulmonares à tomografia computadorizada de alta resolução em pacientes com AR e sua associação com variáveis demográficas, clinicas, sorológicas e terapêuticas. MÉTODO: Estudaram-se 71 pacientes com AR para idade de início da doença, tempo de doença, sexo, tabagismo, presença de nódulos reumatoides, síndrome de Sjögren secundária, fator reumatoide, presença de anti-CCP e fator antinuclear, queixas respiratórias, uso de medicamentos e achados pulmonares à tomografia de alta resolução. RESULTADOS: Existiam alterações tomográficas em 55 por cento dos pacientes, sendo as mais comuns as presenças de vidro fosco, bandas parenquimatosas, bronquiectasias de tração e faveolamento. Nenhuma das variáveis clínicas estudadas se associou aos achados tomográficos, exceto a duração de doença que foi maior em pacientes com nódulos pulmonares e lesões reticulares (vidro fosco). CONCLUSÕES: Existe uma alta prevalência de alterações tomográficas na população de AR, as quais não se associam com variáveis clínicas, sorológicas, terapêuticas e demográficas salvo tempo de duração da doença.
BACKGROUND: Extra-articular manifestations are found in up to 50 percent of the patients with rheumatoid arthritis (RA). OBJECTIVE: To assess the prevalence of pulmonary changes on high-resolution computed tomography (HRCT) in patients with RA and their association with demographic, clinical, serological and therapeutic variables. METHOD: Seventy-one patients with RA were assessed regarding their age at RA onset, duration of disease, gender, tobacco use, presence of rheumatoid nodules, secondary Sjögren's syndrome, rheumatoid factor, presence of anti-CCP and antinuclear factor, respiratory complaints, use of medications, and pulmonary changes on HRCT. RESULTS: HRCT changes were identifi ed in 55 percent of the patients, the most common being the presence of ground glass opacities, parenchymal bands, traction bronchiectasis, and honeycombing. None of the clinical variables studied associated with the HRCT fi ndings, except for duration of the disease, which was longer in patients with pulmonary nodules and reticular lesions (ground-glass opacity). CONCLUSIONS: There is a high prevalence of HRCT changes in patients with RA, which do not associate with clinical, serological, therapeutic and demographic variables, except for duration of disease.
Assuntos
Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Artrite Reumatoide/complicações , Pneumopatias/etiologia , Pneumopatias , Tomografia Computadorizada por Raios X , Pneumopatias/sangue , Pneumopatias/tratamento farmacológico , Pneumopatias/epidemiologia , Estudos RetrospectivosRESUMO
BACKGROUND: Extra-articular manifestations are found in up to 50% of the patients with rheumatoid arthritis (RA). OBJECTIVE: To assess the prevalence of pulmonary changes on high-resolution computed tomography (HRCT) in patients with RA and their association with demographic, clinical, serological and therapeutic variables. METHOD: Seventy-one patients with RA were assessed regarding their age at RA onset, duration of disease, gender, tobacco use, presence of rheumatoid nodules, secondary Sjögren's syndrome, rheumatoid factor, presence of anti-CCP and antinuclear factor, respiratory complaints, use of medications, and pulmonary changes on HRCT. RESULTS: HRCT changes were identified in 55% of the patients, the most common being the presence of ground glass opacities, parenchymal bands, traction bronchiectasis, and honeycombing. None of the clinical variables studied associated with the HRCT findings, except for duration of the disease, which was longer in patients with pulmonary nodules and reticular lesions (ground-glass opacity). CONCLUSIONS: There is a high prevalence of HRCT changes in patients with RA, which do not associate with clinical, serological, therapeutic and demographic variables, except for duration of disease.