RESUMO
Over a four-year period, 26 consecutive patients with Guillain-Barré syndrome (GBS) were seen. Their ages ranged from 18 months to 68 years. Fifteen were male and 11 female. The crude annual incidence was estimated to be 1.5 per 100 000population. East Indians made up the majority of the patients. An antecedent infection was reported in 65% of patients. Significant pain was present in half of the cohort. F-wave abnormalities were the commonest electrophysiological disturbance. Twenty-nine per cent of patients required ventilation. Intravenous immunoglobulin (IVIG) treatment was beneficial in 88% of patients. Eighty-four per cent made a complete or near complete recovery. One patient died.
Por un periodo de cuatro años, se atendieron 26 pacientes consecutivos con el síndrome de Guillain- Barré (GBS). Sus edades fluctuaban de 18 meses a 68 años. Quince eran varones y 11 hembras. Se calculó que la incidencia anual bruta era 1.5 por 100 000 población. La mayor parte de los pacientes eran indo-orientales. El 65% de pacientes reportó antecedentes de infección. La mitad de la cohorte presentaba dolor significativo. El trastorno electrofisiológico más común fue las anormalidades de la onda F. Veintinueve por ciento de los pacientes necesitaron ventilación. El tratamiento de inmunoglobulina intravenosa (IVIG) fue beneficioso en 88% de los pacientes. Ochenta y cuatro por ciento tuvo una recuperación completa o casi completa. Un paciente murió.
Assuntos
Adolescente , Adulto , Idoso , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Síndrome de Guillain-Barré/fisiopatologia , Condução Nervosa , Eletromiografia , Síndrome de Guillain-Barré/tratamento farmacológico , Imunoglobulinas Intravenosas/uso terapêutico , Fatores Imunológicos/uso terapêutico , Estudos Retrospectivos , Trinidad e TobagoRESUMO
Over a four-year period, 26 consecutive patients with Guillain-Barrd syndrome (GBS) were seen. Their ages ranged from 18 months to 68 years. Fifteen were male and 11 female. The crude annual incidence was estimated to be 1.5 per 100,000 population. East Indians made up the majority of the patients. An antecedent infection was reported in 65% of patients. Significant pain was present in halfofthe cohort. F-wave abnormalities were the commonest electrophysiological disturbance. Twenty-nine per cent of patients required ventilation. Intravenous immunoglobulin (IVIG) treatment was beneficial in 88% of patients. Eighty-four per cent made a complete or near complete recovery. One patient died.
Assuntos
Síndrome de Guillain-Barré/fisiopatologia , Condução Nervosa , Adolescente , Adulto , Idoso , Criança , Pré-Escolar , Eletromiografia , Feminino , Síndrome de Guillain-Barré/tratamento farmacológico , Humanos , Imunoglobulinas Intravenosas/uso terapêutico , Fatores Imunológicos/uso terapêutico , Lactente , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Trinidad e Tobago , Adulto JovemRESUMO
A 44 year old female presented with fever, muscle aches, rash and a low platelet count. IgM antibody to dengue virus was positive. Two weeks later she developed a flaccid areflexic quadriparesis. Nerve conduction studies showed a predominantly demyelitinating sensory motor polyneuropathy consistent with Guillain-Barré syndrome. Despite the relatively common occurrence of dengue fever, an associated polyradiculoneuropathy is distinctly uncommon.
Assuntos
Dengue/complicações , Polirradiculoneuropatia/etiologia , Adulto , Anticorpos Antivirais/análise , Doenças Desmielinizantes/fisiopatologia , Dengue/sangue , Dengue/imunologia , Feminino , Humanos , Imunoglobulina M/análise , Condução Nervosa/fisiologia , Contagem de Plaquetas , Polirradiculoneuropatia/fisiopatologia , Reflexo Anormal/fisiologiaRESUMO
A 44 year old female presented with fever, muscle aches, rash and a low platelet count. IgM antibody to dengue virus was positive. Two weeks later she developed a flaccid areflexic quadriparesis. Nerve conduction studies showed a predominantly demyelitinating sensory motor polyneuropathy consistent with Guillain-Barré syndrome. Despite the relatively common occurrence of dengue fever, an associated polyradiculoneuropathy is distinctly uncommon.