RESUMO
Pemphigus foliaceus is one of the most important immune-mediated bullous dermatoses in dogs and cats. The pathogenesis of the disease is well documented in humans and dogs and it is suggested its behavior in felines is similar, characterized by the production of antibodies directed against structures responsible for the maintenance of intercellular adhesion. Although there are reports of several treatment options described in literature for this dermatopathy, most have not been used in studies involving an increased number of animals. Here, we report a case of pemphigus foliaceus in a cat which responded favorably to the treatment used.
O pênfigo foliáceo é uma das formas mais importantes de dermatoses imunomediadas bolhosas em cães e gatos. A patogênese da doença está bem documentada em humanos e cães e sugere-se que em felinos o comportamento seja similar, caracterizado pela produção de anticorpos direcionados contras estruturas responsáveis pela manutenção da adesão intercelular. Embora haja relatos de diversas opções de tratamento descritos na literatura para esta dermatopatia, a maioria não foi utilizada em estudos envolvendo um grande número de animais. Descreve-se um caso de pênfigo foliáceo em um gato que respondeu satisfatoriamente ao tratamento utilizado.
RESUMO
Background: Chondrosarcoma is a malignant neoplasm of mesenchymal origin that generally develops slowly and has a low incidence of metastasis. It was related in dogs, but rarely in small or giant breeds. The most common site of skeletal chondrossarcoma in dogs is the nasal cavity. The lungs are the most common site of metastatic disease, but other organs may be affected. Chondrosarcoma may be classifi ed into primary or secondary according to location in bone, and histologically into mesenchymal and myxoid subtypes. Thus, this study reports the evolution of an uncommon case of chondrossarcoma in a dogs tibia. Case: A 1.4-year-old dog, 58 kg intact-male Brazilian Mastiff was admitted to the veterinary hospital due to lameness and swelling of the stifl e region present for 20 days. Radiographic examination showed lytic bone lesions in the proximal third of the right tibia with periosteal reaction, suggestive of bone tumor. Cytological examination revealed infl ammatory process indicative of acute periostitis. The clinical signs improved after treatment with nonsteroidal anti-infl ammatory (meloxicam, 0.1 mg/kg orally every 24 h) and analgesic (tramadol hydrochloride, 2 mg/kg orally every 8 h) drugs. However, eight months after the initial presentation, the dog had a recurrence of the lameness, and increase in volume and crepitus on palpation of the right knee. Radiographic exami
Background: Chondrosarcoma is a malignant neoplasm of mesenchymal origin that generally develops slowly and has a low incidence of metastasis. It was related in dogs, but rarely in small or giant breeds. The most common site of skeletal chondrossarcoma in dogs is the nasal cavity. The lungs are the most common site of metastatic disease, but other organs may be affected. Chondrosarcoma may be classifi ed into primary or secondary according to location in bone, and histologically into mesenchymal and myxoid subtypes. Thus, this study reports the evolution of an uncommon case of chondrossarcoma in a dogs tibia. Case: A 1.4-year-old dog, 58 kg intact-male Brazilian Mastiff was admitted to the veterinary hospital due to lameness and swelling of the stifl e region present for 20 days. Radiographic examination showed lytic bone lesions in the proximal third of the right tibia with periosteal reaction, suggestive of bone tumor. Cytological examination revealed infl ammatory process indicative of acute periostitis. The clinical signs improved after treatment with nonsteroidal anti-infl ammatory (meloxicam, 0.1 mg/kg orally every 24 h) and analgesic (tramadol hydrochloride, 2 mg/kg orally every 8 h) drugs. However, eight months after the initial presentation, the dog had a recurrence of the lameness, and increase in volume and crepitus on palpation of the right knee. Radiographic exami
RESUMO
Background: Chondrosarcoma is a malignant neoplasm of mesenchymal origin that generally develops slowly and has a low incidence of metastasis. It was related in dogs, but rarely in small or giant breeds. The most common site of skeletal chondrossarcoma in dogs is the nasal cavity. The lungs are the most common site of metastatic disease, but other organs may be affected. Chondrosarcoma may be classifi ed into primary or secondary according to location in bone, and histologically into mesenchymal and myxoid subtypes. Thus, this study reports the evolution of an uncommon case of chondrossarcoma in a dogs tibia. Case: A 1.4-year-old dog, 58 kg intact-male Brazilian Mastiff was admitted to the veterinary hospital due to lameness and swelling of the stifl e region present for 20 days. Radiographic examination showed lytic bone lesions in the proximal third of the right tibia with periosteal reaction, suggestive of bone tumor. Cytological examination revealed infl ammatory process indicative of acute periostitis. The clinical signs improved after treatment with nonsteroidal anti-infl ammatory (meloxicam, 0.1 mg/kg orally every 24 h) and analgesic (tramadol hydrochloride, 2 mg/kg orally every 8 h) drugs. However, eight months after the initial presentation, the dog had a recurrence of the lameness, and increase in volume and crepitus on palpation of the right knee. Radiographic exami
Background: Chondrosarcoma is a malignant neoplasm of mesenchymal origin that generally develops slowly and has a low incidence of metastasis. It was related in dogs, but rarely in small or giant breeds. The most common site of skeletal chondrossarcoma in dogs is the nasal cavity. The lungs are the most common site of metastatic disease, but other organs may be affected. Chondrosarcoma may be classifi ed into primary or secondary according to location in bone, and histologically into mesenchymal and myxoid subtypes. Thus, this study reports the evolution of an uncommon case of chondrossarcoma in a dogs tibia. Case: A 1.4-year-old dog, 58 kg intact-male Brazilian Mastiff was admitted to the veterinary hospital due to lameness and swelling of the stifl e region present for 20 days. Radiographic examination showed lytic bone lesions in the proximal third of the right tibia with periosteal reaction, suggestive of bone tumor. Cytological examination revealed infl ammatory process indicative of acute periostitis. The clinical signs improved after treatment with nonsteroidal anti-infl ammatory (meloxicam, 0.1 mg/kg orally every 24 h) and analgesic (tramadol hydrochloride, 2 mg/kg orally every 8 h) drugs. However, eight months after the initial presentation, the dog had a recurrence of the lameness, and increase in volume and crepitus on palpation of the right knee. Radiographic exami