RESUMO
Crude extracts of Haplopappus sonorensis (A. Gray) S.F. Blake (Asteraceae), showed activity against Mycobacterium tuberculosis H(37)Rv. By assay-guided fractionation, 5-hydroxy-3,7,4'-trimethoxyflavone (1). 5,7-dihydroxy-3,4'-dimethoxyflavone (2). and 5,4'-dihydroxy-3,7-dimethoxyflavone (3). were identified as the antimycobacterial principles. Compound 2 was the most active compound.
Assuntos
Antituberculosos/farmacologia , Flavonoides/farmacologia , Haplopappus , Mycobacterium tuberculosis/efeitos dos fármacos , Fitoterapia , Extratos Vegetais/farmacologia , Humanos , Testes de Sensibilidade Microbiana , Células Tumorais Cultivadas/efeitos dos fármacosRESUMO
The ethanolic extracts of 72 plants belonging to 35 different families, and used in traditional medicine in Baja California Sur (México), were tested for antimicrobial activity in vitro using the filter paper disk assay method. Activity against Staphylococcus aureus, Bacillus subtilis, Streptococcus faecalis (Gram-positive microorganisms), Escherichia coli (Gram-negative microorganisms) and Candida albicans (yeast) is discussed.
Assuntos
Antibacterianos , Plantas Medicinais , Antibacterianos/isolamento & purificação , Medicina Tradicional , México , Testes de Sensibilidade Microbiana , Extratos Vegetais/farmacologiaRESUMO
Continuing our studies of traditional medicine, as used in rural areas of Baja California Sur, now we wish to report on the medicinal uses of 49 more plants. Some of the more complex recipes of these medicinal plants, are discussed in the present paper. The information presented here was collected in the Municipio of Los Cabos and part of the Municipio of La Paz, B.C.S., Mexico.