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1.
Foot Ankle Surg ; 26(7): 750-754, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31640921

RESUMO

BACKGROUND: We aimed to clinically evaluate the effect of platelet-rich plasma (PRP) therapy in patients with acute lateral ankle sprain treated with rigid immobilization. METHODS: Patients with first-time grade II lateral ankle sprain clinically diagnosed were evaluated (n=21). A rigid immobilization was placed in all patients for ten days; previously, an application of PRP over the anterior talofibular ligament was performed in patients from the experimental group. The Visual Analogue Scale, the American Orthopedic Foot and Ankle Score, and the Foot and Ankle Disability Index were applied at 3, 5, 8 and 24 weeks of follow-up period. RESULTS: The experimental group presented the highest reduction in pain and better functional scores than the control group at 8 weeks. At the end of follow-up period the results of both groups were similar. CONCLUSIONS: A similar evolution was observed in patients treated with rigid immobilization with or without PRP after 24 weeks. TRIAL REGISTRATION: Clinical Trials.gov with ID NCT02609308.


Assuntos
Traumatismos do Tornozelo/terapia , Articulação do Tornozelo/diagnóstico por imagem , Ligamentos Laterais do Tornozelo/lesões , Plasma Rico em Plaquetas , Adulto , Traumatismos do Tornozelo/diagnóstico , Feminino , Humanos , Masculino , Resultado do Tratamento
2.
Foot Ankle Int ; 34(1): 8-14, 2013 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-23386757

RESUMO

BACKGROUND: The objective of this study was to compare intramuscularly applied botulinum toxin A (BTX-A) in the gastroc-soleus complex with intralesional steroids for the treatment of plantar fasciitis. METHODS: The patients were randomly divided into 2 groups according to the treatment received. The patients were evaluated over 6 months. The evaluation scores included the Visual Analog Scale (VAS), Maryland Foot and Ankle, Foot and Ankle Disability Index (FADI), and American Orthopaedic Foot and Ankle Society (AOFAS) score. Moreover, patients were instructed to perform plantar fascia stretching exercises over the course of the study. The final number of patients was 36, of whom 19 received BTX-A (10 men and 9 women) and 17 (6 men and 11 women) received steroids. RESULTS: When compared to patients who received steroids, the patients who received BTX-A exhibited more rapid and sustained improvement over the duration of the study. CONCLUSION: A combination of BTX-A and plantar fascia stretching exercises yielded better results for the treatment of plantar fasciitis than intralesional steroids. LEVEL OF EVIDENCE: Level I, therapeutic studies.


Assuntos
Toxinas Botulínicas Tipo A/uso terapêutico , Isonicotinato de Dexametasona/uso terapêutico , Fasciíte Plantar/terapia , Glucocorticoides/uso terapêutico , Fármacos Neuromusculares/uso terapêutico , Adulto , Análise de Variância , Avaliação da Deficiência , Método Duplo-Cego , Feminino , Humanos , Injeções Intralesionais , Injeções Intramusculares , Masculino , Pessoa de Meia-Idade , Exercícios de Alongamento Muscular , Estudos Prospectivos
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