RESUMO
Beta-lactamase-producing (Bla+) enterococci have been reported in three state and two countries. Pulsed-field gel electrophoresis was used to compare 14 Bla+ Enterococcus (Streptococcus) faecalis isolated from hospitalized patients in seven states and three continents. The restriction endonuclease digestion patterns of isolates from Connecticut, Massachusetts, Lebanon, and Argentina were all markedly different, indicating that these were different strains. However, isolates from Delaware, Texas, Pennsylvania (Philadelphia and Pittsburgh), Florida, and Virginia were similar, indicating that these isolates were derivatives of a single strain. This conclusion was supported by hybridization using individual fragments as probes. Spread of Bla+ enterococci within the hospital setting was also demonstrated. These findings illustrate the value of pulsed-field gel electrophoresis for epidemiologic analyses and support the importance of identifying and containing organisms with new resistance properties in an effort to decrease their transmission to and from, as well as within, hospitals.
Assuntos
DNA Bacteriano/análise , Enterococcus faecalis/classificação , Infecções Estreptocócicas/microbiologia , beta-Lactamases/biossíntese , Argentina , Boston , Connecticut , Delaware , Eletroforese em Gel de Ágar , Enterococcus faecalis/enzimologia , Enterococcus faecalis/genética , Florida , Humanos , Líbano , Hibridização de Ácido Nucleico , Pennsylvania , Philadelphia , Plasmídeos , Mapeamento por Restrição , Infecções Estreptocócicas/transmissão , Texas , VirginiaRESUMO
En este trabajo se revisa la bacteriología y patogenesis de las infecciones del pie en el diabético y se intenta assiliar a una comprensión socio-real de las opciones que presenta la antibióticoterapia. Se concluye que para obtener resultados óptmos en el tratamiento de estas ionfeciones se requiere un enfoque clinicoquirurgico combinado con el uso emféccio de antibióticos en forma temprana
Assuntos
Adulto , Humanos , Masculino , Feminino , Antibacterianos/uso terapêutico , Infecções Bacterianas/terapia , Diabetes Mellitus/complicações , Pé/patologiaRESUMO
En este trabajo se revisa la bacteriología y patogenesis de las infecciones del pie en el diabético y se intenta assiliar a una comprensión socio-real de las opciones que presenta la antibióticoterapia. Se concluye que para obtener resultados óptmos en el tratamiento de estas ionfeciones se requiere un enfoque clinicoquirurgico combinado con el uso emféccio de antibióticos en forma temprana (AU)