RESUMO
INTRODUCTION: Neonatal polysomnography studies (electroencephalogram, electrooculography, body movements, cardiorespiratory frequencies) were performed in 101 newborn full-term infants diagnosed with severe birth asphyxia. PATIENTS AND METHODS: To analyse results, the sample was divided into two groups, depending on whether hypoxic-ischaemic encephalopathy (HIE) had occurred or not. The results of the polysomnography studies were correlated with those from the full-term neurological examination and the sequelae from the neurological development during the first two years of life. RESULTS: Significant correlations were obtained among the variables that were studied. The normality observed in the electrophysiological study in the group of patients with severe asphyxia without HIE was associated with a full-term neurological examination and with a neurological development that has progressed in a satisfactory manner. In the group of patients with grade II HIE there was a predominance of severe alterations in the full-term neonatal polysomnography study, which were significantly correlated with the pathological full-term neurological examinations and serious sequelae from neurological development. CONCLUSIONS: It has been proved that neonatal polysomnography studies are a valuable aid in evaluating the neurological status of newborn infants in a critical condition and in predicting the sequelae of neurological development in the first two years of life. Further research should be aimed at determining the effects exerted by the daily administration of medication (sedatives, anaesthetics and antiepileptic agents) in critical newborn infants on electrical activity in the brain and the cyclic structuring of the different phases of sleep.
Assuntos
Asfixia Neonatal/fisiopatologia , Hipóxia-Isquemia Encefálica/fisiopatologia , Polissonografia , Eletroencefalografia , Feminino , Idade Gestacional , Humanos , Lactente , Recém-Nascido , Estudos Longitudinais , Masculino , Exame Neurológico , Gravidez , Estudos Prospectivos , Estatística como AssuntoRESUMO
During 1992-1994, 33 malaria cases were reported in two regions in Brazil where few sporadic atypical cases occur, most of them in home owners, who are weekenders, while home caretakers live there permanently. Indirect Fluorescent Antibody Test (IFAT), with Plasmodium vivax, and Enzime Linked Immunosorbent Assay (ELISA) with repeat peptides of the circumsporozoite (CS) proteins of the 3 known P. vivax variants and P. malarie/P. brasilianum, were performed on 277 sera, obtained within a 5 to 10 km range of malaria cases. Very rarely did any of these donors recall typical malaria episodes. Blood smears of all but 5 were negative. One of the 5 malaria cases included in our serology was of a home owner, I of a permanent resident, 3 from Superintendência de Controle de Endemias employees who went there to capture mosquitoes. In Region 1 the prevalence of IFAT positive sera was 73% and 28% among caretakers, 18% and 9.6% among home owners. In Region 2 (3 localities) no distinction was possible between caretakers and home owners, IFAT positivity being 38%, 28% and 7%. The relative percentage of positive anti-CS repeats ELISA, differed for each of the peptides among localities. Dwellings are in the vicinity of woods, where monkeys are frequently seen. The origin of these malaria cases, geographical differences and high seropositivity is discussed.
Assuntos
Anticorpos Antiprotozoários/sangue , Antígenos de Protozoários/sangue , Malária/sangue , Malária/epidemiologia , Plasmodium malariae/imunologia , Plasmodium vivax/imunologia , Adolescente , Adulto , Animais , Brasil/epidemiologia , Humanos , Malária/diagnóstico , PrevalênciaRESUMO
The neuropathological manifestations of AIDS in children vary widely and includes, among others: cerebral atrophy, basal ganglia calcification, corticospinal tract demyelinization, and HIV encephalomyelitis with multinucleated cells. The purpose of this work is to inform the postmortem CNS findings in 14 pediatric AIDS patients which were studied from January 1986 to February 1992, at the Hospital Infantil de México Federico Gómez. Basal ganglia vascular calcification, HIV multinucleated cells, and corticospinal tract demyelinization, were significantly less frequent (P < 0.01) in our patients than those informed in the literature. Opportunistic CNS infections found in our patients were produced by microorganisms commonly described in adults. We think that these differences may be explained because the majority of our patients acquired the infection trough blood transfusion at an age in which the CNS is fully developed. The pattern of HIV transmission in our country has been changing recently with an increase in the number of perinatal cases. We also think that in the near future we will observe a change in the neuropathological findings of our pediatric AIDS population.
Assuntos
Síndrome da Imunodeficiência Adquirida/patologia , Sistema Nervoso Central/patologia , Adolescente , Autopsia , Criança , Pré-Escolar , Humanos , Lactente , Estudos RetrospectivosRESUMO
A rotating wheel cage for rats which permits voluntary physical activity and free access to food and water is described. The cyclometer is entirely mechanical and does not require an external energy source. The apparatus can be constructed from commercially available, inexpensive components.
Assuntos
Ingestão de Líquidos , Ingestão de Alimentos , Abrigo para Animais , Atividade Motora , Animais , Masculino , Ratos , Ratos Endogâmicos , Restrição FísicaRESUMO
A rotating wheel cage for rats which permits voluntary physical axtivity and free access to food and water is decribed. The cyclometer is entirely mechanical and does not requiere an external energy source. The apparatus can be constructed from commercially available, inexpensive components
Assuntos
Ratos , Animais , Masculino , Bebidas , Ingestão de Alimentos , Abrigo para Animais , Atividade Motora , Ratos Endogâmicos , Restrição FísicaAssuntos
Humanos , Masculino , Feminino , Colecistectomia , Fluxômetros , Período Intraoperatório , ManometriaRESUMO
Los autores presentan un caso de sindrome de Sezary. Se hace una revision de los caracteres clinicos, citohematologicos, patologicos del cuadro y se plantean distintas posibilidades terapeuticas. Se mencionan los diferentes intentos de ubicacion nosologica de esta entidad.Se llega a la conclusion de encuadrarlo dentro de los linfomas cutaneos a linfocitos T (L.C.L.T) con identidad propia, separandolo de la micosis fungoide
Assuntos
Idoso , Humanos , Masculino , Dermatite Esfoliativa , Prednisona , Síndrome de SézaryRESUMO
Los autores presentan un caso de sindrome de Sezary. Se hace una revision de los caracteres clinicos, citohematologicos, patologicos del cuadro y se plantean distintas posibilidades terapeuticas. Se mencionan los diferentes intentos de ubicacion nosologica de esta entidad.Se llega a la conclusion de encuadrarlo dentro de los linfomas cutaneos a linfocitos T (L.C.L.T) con identidad propia, separandolo de la micosis fungoide
Assuntos
Idoso , Humanos , Masculino , Dermatite Esfoliativa , Prednisona , Síndrome de SézaryRESUMO
Foram dissecadas macroscopicamente e sob estereomicroscopio 21 pecas anatomicas.Estabelecemos a morfologia do aparelho extensor do polegar constituido de tres porcoes: asa radial, asa ulnar e porcao central. Foi analisada a participacao funcional destas estruturas em relacao as articulacoes metacarpo-falangica e inter-falangica