RESUMO
The relative efficacy of fluorescent green (Sylvania F20T12/G) and "special" blue (Westinghouse F20T12/BB) lamps in the phototherapy of jaundiced neonates was investigated. Two groups of low birth weight infants with a mean gestational age of 35 weeks and mean birth weight of 1930 gm, who developed hyperbilirubinemia within the first 5 days of life, were given green or blue lamp phototherapy under the same irradiation conditions. No statistically significant difference in plasma bilirubin concentrations was found between the two groups after 24 or 48 hours of treatment. Because recent measurements indicate that green lamps are much less efficient than special blue lamps for the production of Z, E isomers of bilirubin in vitro and in vivo, the clinical equivalence of these two types of lamps seems to support the hypothesis that production of structural photoisomers of bilirubin is the main mechanism of phototherapy in humans. Therefore, fluorescent green lamps provide an alternative to special blue lamps for treatment of neonatal hyperbilirubinemia.
Assuntos
Doenças do Prematuro/terapia , Icterícia Neonatal/terapia , Fototerapia/métodos , Bilirrubina/sangue , Cor , Estudos de Avaliação como Assunto , Fluorescência , Humanos , Recém-Nascido de Baixo Peso , Recém-NascidoRESUMO
The author's relieve the increase of number of the cases of malaria verified during the previous years in Italy, in subjects coming from malaria regions. The social and medical implications of this phenomenon are remarked. Epidemiology, pathology, immunology, clinical features and therapy of "imported malaria" are briefly elucidated. The new refined methods for the diagnosis (serological tests: Immunofluorescence - FAT and IFA - Enzyme linked immuno-sorbent assay - Elisa - Radio-immuno assay, Merozoite inhibition in culture) are described. The elaboration of a human malaria vaccine is analysed theoretically and practically. The imported malaria is a disease that every physician must recognize and treat.