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Nat Prod Res ; 29(10): 939-46, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25280163

RESUMO

The essential oils (EOs) from the Brazilian species Croton zehntneri, Pterodon emarginatus and Schinopsis brasiliensis were examined for their chemical constituents, and antioxidant and antimicrobial activities. The composition of EOs was determined by using gas chromatography coupled with mass spectrometry analysis, while the antioxidant activity was evaluated through the 1,1-diphenyl-2-picrylhydrazyl (DPPH) and oxygen radical absorbance capacity (ORAC) assays. Furthermore, the antimicrobial activity was investigated against Escherichia coli and Pseudomonas aeruginosa (both Gram-negative), Staphylococcus aureus (Gram-positive) and Candida parapsilosis (fungus). The main components of C. zehntneri, P. emarginatus and S. brasiliensis were identified as estragole, trans-anethole, ß-caryophyllene and myrcene. Among the EOs, P. emarginatus showed the highest antioxidant activity, with an IC50 of 7.36 mg/mL and a Trolox equivalent antioxidant capacity of 3748 µmol/g determined by DPPH and ORAC assays, respectively. All EOs showed low activities against the bacterial strains tested, whereas the C. zehntneri oil and its main constituent estragole exhibited an appreciable antifungal activity against C. parapsilosis.


Assuntos
Antibacterianos/farmacologia , Antifúngicos/farmacologia , Croton/química , Fabaceae/química , Sequestradores de Radicais Livres/farmacologia , Óleos Voláteis/química , Monoterpenos Acíclicos , Alcenos/farmacologia , Derivados de Alilbenzenos , Anacardiaceae/química , Anisóis/farmacologia , Candida/efeitos dos fármacos , Escherichia coli/efeitos dos fármacos , Espectrometria de Massas , Testes de Sensibilidade Microbiana , Monoterpenos/farmacologia , Sesquiterpenos Policíclicos , Pseudomonas aeruginosa/efeitos dos fármacos , Sesquiterpenos/farmacologia , Staphylococcus aureus/efeitos dos fármacos
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