Assuntos
COVID-19 , Melanoma , Estudos de Coortes , Humanos , Melanoma/diagnóstico , Melanoma/epidemiologia , Pandemias , SARS-CoV-2RESUMO
Resumen Introducción: La duodeno pancreatectomía cefálica es una operación compleja cuyos resultados a corto plazo son multifactoriales. Objetivo: Evaluar el impacto de la curva de aprendizaje en los resultados a corto plazo de la duodenopancreatectomía cefálica en un hospital de nivel II. Materiales y Método: Se analizaron los datos obtenidos a partir de una base de datos mantenida prospectivamente desde 2005. Se definieron dos periodos de tiempo: de 2005 a 2011 y de 2012 a 2017. Se compararon la morbilidad, mortalidad y estancia postoperatoria de ambos períodos. Resultados: Durante el período de tiempo estudiado se hicieron 126 duodenopancreatectomías cefálicas, 61 durante la primera etapa y 65 durante la segunda. La tasa de transfusión intraoperatoria se redujo de 33% a 15% (p = 0,011). La tasa de transfusión postoperatoria se redujo de 39 a 23% (p = 0,021). No hubo diferencias significativas con respecto a la incidencia global de complicaciones postoperatorias (59% y 52,3%). La incidencia de abscesos intraabdominales fue significativamente menor en el segundo período (18% y 4,6%, respectivamente; p = 0,038). La tasa de reintervenciones se redujo significativamente, de 22% a 9% (p = 0,049). También se redujo significativamente la tasa de mortalidad, de 6,56% a 0% (p = 0,032). La estancia media postoperatoria disminuyó significativamente en el segundo período, pasando de 19,6 a 15,8 días (p = 0,001), con una mayor proporción de pacientes dados de alta en los 8 primeros días de postoperatorio (11,5% y 38,5%, respectivamente; p = 0,001). Conclusión: La curva de aprendizaje es un factor que permite mejorar los resultados de la duodenopancreatectomía cefálica, en un hospital de nivel II, hasta alcanzar valores similares a los de un hospital de nivel III.
Introduction: The duodenum pancreatectomy cephalic is a complex operation whose short-term results are multifactorial. Aim: To assess the impact of the learning curve on the short-term outcomes of cephalic duodenopancreatectomy at a level II hospital. Materials Method: We analyze the data obtained from a database maintained prospectively since 2005. Two time periods were defined: from 2005 to 2011 and from 2012 to 2017. The morbidity, mortality and postoperative stay of both periods were compared. Results: 126 cephalic duodenopancreatectomies were performed, 61 during the first period and 65 during the second. The intraoperative transfusion rate was reduced from 33% to 15% (p = 0.011). The postoperative transfusion rate was reduced from 39 to 23% (p = 0.021). There were no significant differences with respect to the overall incidence of postoperative complications (59% and 52.3%, respectively). However, the incidence of intra-abdominal abscesses was significantly lower in the second period (18% and 4.6%, respectively, p = 0.038). The rate of reoperations was significantly reduced, from 22% to 9% (p = 0.049). The mortality rate was also significantly reduced, from 6.56% to 0% (p = 0.032). The mean postoperative stay decreased significantly in the second period, from 19.6 to 15.8 days (p = 0.001), with a higher proportion of patients discharged in the first 8 postoperative days (11.5% and 38.5%, respectively, p = 0.001). Conclusion: The learning curve is a factor allows improving the results of cephalic pancreaticoduodenectomy, in a level II hospital, until reaching values similar to those of a level III hospital.
Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Neoplasias Pancreáticas/cirurgia , Neoplasias Pancreáticas/complicações , Pancreaticoduodenectomia/efeitos adversos , Curva de Aprendizado , Período Pós-Operatório , Pancreaticoduodenectomia/educação , Pancreaticoduodenectomia/métodos , Pancreaticoduodenectomia/mortalidadeRESUMO
Variations in the mRNA expression of hepatic and muscle genes that are related to calcium signaling were analyzed by real-time qPCR in farmed Atlantic salmon (Salmo salar L. 1758) to determine changes in expression between parr and smolt stages. These organs were selected due to their close relationship with calcium signaling and metabolism (e.g., glycolysis, oxidative phosphorylation, muscle contraction). Differential expression between smolt and parr specimens and between organs was observed. Compared to parr specimens, smolts exhibited upregulated expression of the calcitonin receptor precursor, calcitonin receptor, calcitonin isoform, parathyroid hormone, and calmodulin in the liver. This pattern was inverse in muscle, with the exception of calmodulin, which was significantly upregulated in smolts compared to parr. Additionally, plasma calcium was decreased in the smolt condition. This study is the first to characterize the expression pattern of calcium signaling-related genes in the liver and muscle of parr and smolt S. salar. However, further functional studies are required to obtain a wider understanding about the physiological changes that accompany the productive conditions during smoltification.
Assuntos
Sinalização do Cálcio/genética , Regulação da Expressão Gênica no Desenvolvimento , Salmo salar/crescimento & desenvolvimento , Salmo salar/genética , AnimaisRESUMO
OBJECTIVE: The aim of this study was to assess the association of overweight and obesity with insulin resistance, hypertension, and hyperlipidemic among 12 to 15 year olds from private and public schools in Chiapas. METHODS: This was a cross-sectional study with a random selection of 259, 12 to 15 year old teenagers from private and public middle schools. Conventional methods were used to measure body weight, height and blood pressure. After a 14-hour fasting period, a blood sample was taken for glucose, total lipids, total cholesterol, LDL-cholesterol, triglycerides and insulin levels. HDL-cholesterol and HOMA-IR were estimated. Weight-for-age, height-for-age and BMI-for-age were calculated using the CDC tables for growth. To assess the difference between overweight and obesity by gender and type of school a X2 and t-test was performed in order to evaluate the mean difference between biochemical indicators of normal and overweight adolescents. The Mann-Whitney test was conducted to assess differences in blood pressure. RESULTS: Observations included high prevalence of overweight (19%) and obesity (13%) with no difference between type of school, gender, or group of age (Table 2). High prevalence of hipercholesterolemia (26%), LDLcholesterol (7%), HDL hypolipoproteinemia (3%), triglycerides (10%), systolic blood pressure (6%), and metabolic syndrome (1.6%) were also observed. The BMI was associated to total lipid, total cholesterol, insulin, and HOMA-IR levels. The Overweight and obese had higher levels of insulin, HOMA-IR, triglycerides, and blood pressure and lower levels of HDL-cholesterol.
Assuntos
Resistência à Insulina , Sobrepeso/metabolismo , Adolescente , Criança , Feminino , Humanos , Hiperlipidemias/complicações , Hipertensão/complicações , Masculino , México , Obesidade/complicações , Obesidade/metabolismo , Sobrepeso/complicaçõesRESUMO
Neisseria meningitidis isolates are conventionally classified by serosubtyping, which characterizes the reactivities of the PorA outer membrane protein variable-region epitopes with monoclonal antibodies (MAbs). New murine hybridomas, secreting specific MAbs against PorA of N. meningitidis serogroup B, were generated using conventional hybridoma procedures. Using outer membrane protein as antigen, we obtained two positive clones, and one of them we characterized. This MAb reacted, on whole-cell enzyme-linked immunosorbent assay (ELISA) and immunoblotting, only with strain subtype P1.15 and its IgG2b isotype. This MAb demonstrated bactericidal activity against the homologous strain in the presence of human complement.
Assuntos
Anticorpos Monoclonais/metabolismo , Vacinas Bacterianas/imunologia , Neisseria meningitidis/imunologia , Porinas/imunologia , Animais , Anticorpos Monoclonais/biossíntese , Anticorpos Monoclonais/química , Feminino , Hibridomas , Camundongos , Camundongos Endogâmicos BALB CRESUMO
Magnolia dealbata Zucc. is considered to have tranquilizer and anticonvulsant properties in Mexican traditional medicine. In the present study we report the effects of a crude extract of Magnolia dealbata (30, 100 and 300 mg/kg) on mouse central nervous system (CNS). Pharmacological effects were tested on ambulatory activity, anti-anxiety response, sodium pentobarbital-induced hypnosis and pentylenetetrazole (PTZ)-induced seizures in comparison to honokiol, buspirone, ethosuximide and diazepam as corresponding reference drugs. No changes in spontaneous locomotor activity were produced posterior to Magnolia dealbata administration; however, a significant and dose-dependent diminution in the anxiety response was observed in experimental models such as plus-maze, head-dipping and exploratory rearing tests. Magnolia dealbata not only prolonged the time of sodium pentobarbital-induced hypnosis and delayed the onset of PTZ-induced mioclonus and clonus, but also hindered the presence of tonic seizures and avoided mortality. The hypnotic, anxiolytic and anticonvulsant effects obtained in these experiments support the hypothesis that Magnolia dealbata possesses CNS activity and reinforces the popular use in Mexican traditional medicine.
Assuntos
Ansiolíticos/farmacologia , Anticonvulsivantes/farmacologia , Hipnóticos e Sedativos/farmacologia , Magnolia , Extratos Vegetais/farmacologia , Animais , Ansiolíticos/toxicidade , Anticonvulsivantes/toxicidade , Diazepam/farmacologia , Relação Dose-Resposta a Droga , Etanol , Hipnóticos e Sedativos/toxicidade , Dose Letal Mediana , Masculino , Aprendizagem em Labirinto/efeitos dos fármacos , Camundongos , Pentobarbital , Pentilenotetrazol , Extratos Vegetais/toxicidade , Folhas de Planta , Convulsões/induzido quimicamente , Convulsões/prevenção & controle , Sono/efeitos dos fármacos , Solventes , Fatores de TempoRESUMO
SETTING: In developing countries, tuberculosis is diagnosed by identification of acid-fast bacilli (AFB) on sputum smears. OBJECTIVE: To evaluate the quality of AFB microscopy, the Mexican Secretary of Health National Reference Laboratory implemented proficiency testing for its network of 637 laboratories. DESIGN: A total of 586 (92%) laboratories were inspected and 430 technicians evaluated by proficiency testing consisting of 10 slides with known numbers of AFB. Results were compared with those of slide rechecking and with proficiency testing performed 2 years later. RESULTS: Of the 430 technicians evaluated by proficiency testing in 1998, 196 (46%) scored less than 80% and received intensive training in 1999. From a previous mean score of 65% their results increased to 90% (P < 0.0001). In 2001, they again underwent proficiency testing, and the mean score was 83%. The main factors affecting proficiency testing results were the type of laboratory in which the microscopists worked and the number of low-positive slides (1-9/100) in the test. Laboratories whose work was rechecked had better scores (P = 0.002). Proficiency testing scores and the estimated sensitivity of the microscopist's laboratory were associated (P = 0.01). CONCLUSION: External quality assessment and training improve diagnostic performance. Rechecking and proficiency testing are both viable measures of laboratory performance.
Assuntos
Competência Clínica , Técnicas de Laboratório Clínico , Implementação de Plano de Saúde , Microscopia , Avaliação de Programas e Projetos de Saúde , Garantia da Qualidade dos Cuidados de Saúde , Tuberculose Pulmonar/microbiologia , Tuberculose Pulmonar/patologia , Humanos , México , Mycobacterium tuberculosis/isolamento & purificação , Reprodutibilidade dos Testes , Escarro/citologia , Escarro/microbiologia , Análise de SistemasRESUMO
OBJECTIVE: To present a case of solitary pelvic kidney with congenital absence of the vagina. METHODS: A patient with solitary pelvic kidney and vaginal aplasia is described. Patient evaluation included hematological, hormonal, cytogenetic, laparoscopic and imaging studies. RESULTS: Blood, hormone and cytogenetic studies were normal. Laparoscopy showed absence of the uterus and both tubes and ovaries, which was confirmed by pneumopyelography. IVP showed absence of renal shadows and a solitary pelvic kidney. CONCLUSIONS: Congenital absence of the vagina should be suspected in a patient with a pelvic solitary kidney consulting for primary amenorrhea.
Assuntos
Anormalidades Múltiplas/diagnóstico , Rim/anormalidades , Vagina/anormalidades , Adulto , Feminino , HumanosRESUMO
Prothymosin alpha (PTA) was detected by immunocytological and biochemical methods in oocytes at different stages of oogenesis, and in early embryos of the amphibian Bufo anenarum. In all cases PTA was detected in the nucleus and was absent from the cytoplasm. This indicates that this protein could act at the level of regulating transcription. Western blots were carried out using polyclonal antibodies with extracts of embryos at different stages of development from early fertilisation up to neural tube. With this method PTA was detected in all the samples under study.
Assuntos
Bufo arenarum/metabolismo , Embrião não Mamífero/metabolismo , Oócitos/metabolismo , Precursores de Proteínas/metabolismo , Timosina/análogos & derivados , Animais , Western Blotting , Bufo arenarum/embriologia , Núcleo Celular/metabolismo , Citoplasma/metabolismo , Feminino , Imuno-Histoquímica , Timosina/metabolismoRESUMO
OBJECTIVE: To describe a case of crossed testicular ectopia that was diagnosed in a 52-year-old patient who had consulted for infertility associated with a genital anomaly. METHODS: Patient evaluation included hematological, hormonal, cytogenetic and imaging studies. An exploratory operation was also performed. RESULTS: The hematological, hormonal and cytogenetic studies gave normal results. There were no urinary tract abnormalities in the intravenous urography; retrograde urethrography disclosed a narrow duct behind the urethra that ascended towards the left inguinal duct and divided into two epididymides after reaching the scrotum. Surgical exploration showed two testes in the left scrotal pouch that were biopsied. Histological examination revealed an almost complete hyalinization of the tubular wall with no germ cells within the tubules. CONCLUSIONS: Crossed testicular ectopia is one of the most uncommon testicular anomalies and is often associated with other disorders such as inguinal hernia, hypospadias, pseudohermaphroditism and scrotal abnormalities. Like all dysgenetic testes, progression to malignancy is relatively frequent. The foregoing should be remembered when dealing with these patients.
Assuntos
Testículo/anormalidades , Transtornos do Desenvolvimento Sexual/diagnóstico , Ginecomastia/diagnóstico , Humanos , Infertilidade Masculina/diagnóstico , Masculino , Pessoa de Meia-Idade , Oligospermia/diagnósticoRESUMO
OBJECTIVES: A case of bilateral ectopic pelvic kidney is presented whose clinical symptoms were hypogastric pain and cloudy urine. The few cases reported in the world medical literature are briefly reviewed. METHODS: Patient evaluation included intravenous urography, selective right renal arteriography and transoperative left antegrade pyelography. A left nephrectomy was performed. RESULTS: All symptoms disappeared after nephrectomy. CONCLUSIONS: Bilateral ectopic pelvic kidneys are uncommon as shown by the few cases reported in the literature. To our knowledge, the present case is the first case reported in the Spanish literature.
Assuntos
Rim/anormalidades , Adulto , Humanos , MasculinoRESUMO
With the objective of evaluating and accrediting the quality of medical education in the country, the Mexican Association of Medical Schools initiated the National Programme for the Strengthening of the Quality of Medical Education (PNFCE). This programme led to the establishment of the National System of Accreditation. Medical school deans in Mexico determined the criteria for the evaluation of quality and its subsequent standards through a consensus process. The following 10 criteria resulted: general basis and educational objectives; government and institutional orientation; educational programme and academic structure; educational process assessment; students; teaching staff; institutional coherence; resources; clinical sites; and administration. Eighty-eight standards were developed in the instrument designed for the self-evaluation phase. The information resulting from the self-evaluation will be verified by a group of experts during a survey visit, which will be finalized with a report to serve as the basis for the decision to be made by the Accreditation Commission. The self-evaluation phase started in 1994. In 1996 four schools submitted their request for accreditation. As of July 1996, one survey visit has been completed and three more are programmed for the second half of the year.
Assuntos
Acreditação , Educação Médica/normas , Faculdades de Medicina/normas , México , Controle de QualidadeRESUMO
OBJECTIVES: The aim of this study was to review a large series of ameloblastomas, accessioned during a period of 35 years in a single Oral Pathology Diagnostic Center, for the incidence of desmoplastic ameloblastoma (DA) and in order to analyze the clinical features of this unusual variant. MATERIALS AND METHODS: All cases diagnosed as ameloblastoma were reviewed and 14 were rediagnosed as DA. These cases were analyzed in terms of gender, patient age, location, clinical diagnosis, radiographic features and recurrence following treatment. Data from DA and non-desmoplastic ameloblastoma (NDA) were compared. RESULTS: The incidence of DA in this series was 8.8%. The mean age of NDA and DA were 39.1 and 38.8 years respectively, and a higher female prevalence was observed in the latter. The mandible was the most affected bone in both groups of tumors, but with a different regional distribution. Most NDA arose in the angle and ramus of the mandible, but the premolar/molar region was the preferential location for DA. The most common radiographic feature in DA was the osteolytic type, either monolocular or multilocular. Most of these cases were clinically diagnosed as ameloblastoma. According to follow-up data available, 21.4% of DA and 10.1% of NDA recurred. CONCLUSIONS: The results of this study do not support the hypothesis that DA should be a separate clinicopathological entity. It seems most likely that DA is another histologic variant of ameloblastoma.
Assuntos
Ameloblastoma/classificação , Ameloblastoma/patologia , Neoplasias Maxilomandibulares/classificação , Neoplasias Maxilomandibulares/patologia , Adolescente , Adulto , Distribuição por Idade , Idoso , Idoso de 80 Anos ou mais , Ameloblastoma/epidemiologia , Criança , Pré-Escolar , Feminino , Humanos , Incidência , Neoplasias Maxilomandibulares/epidemiologia , Masculino , Pessoa de Meia-Idade , Recidiva Local de Neoplasia , Estudos Retrospectivos , Distribuição por Sexo , Células Estromais/patologiaAssuntos
Displasia Fibrosa Óssea/genética , Doenças Mandibulares/genética , Neoplasias Mandibulares/genética , Tumores Odontogênicos/genética , Adolescente , Diagnóstico Diferencial , Displasia Fibrosa Óssea/patologia , Displasia Fibrosa Óssea/cirurgia , Humanos , Masculino , Doenças Mandibulares/patologia , Doenças Mandibulares/cirurgia , Neoplasias Mandibulares/patologia , Neoplasias Mandibulares/cirurgia , Pessoa de Meia-Idade , Tumores Odontogênicos/patologia , Tumores Odontogênicos/cirurgia , LinhagemRESUMO
El objetivo de este trabajo fue determinar la prevalencia de bocio en escolares de la ciudad de Mar del Plata. Se seleccionó una muestra entre alumnos de 6 a 14 años de edad de escuelas urbanas y periurbanas de la ciudad de Mar del Plata; la muestra se realizó por conglomerados y posteriormente por métodos aleatorios. Se encuestaron 889 alumnos, 54,1 por ciento de sexo masculino y 45,9 por ciento del femenino, y se recolectó orina en un 8,7 por ciento de los varones. Se detectó un 17,2 por ciento del nivel Ia, 1,7 por ciento Ib y 0,1 por ciento II Total = 19 por ciento (según clasificación OPS). No se observaron diferencias significativas respecto al sexo y edad, ni a la provisión de agua corriente y/o de pozo ni a residencia urbana o rural. Si se observó diferencia significativa entre escuelas Estatales y Privadas : 21,2 por ciento y 11,6 por ciento respectivamente. Dado las diferencias observadas entre los distintos equipos de trabajo (todos los profesionales intervinientes con experiencia en palpación de tiroides), se resolvió efectuar ecografía a un 20 por ciento de los positivos más un 10 por ciento de normales : los resultados de las ecografías avalan ampliamente los hallazgos palpatorios. De las 53 muestras de orina procesadas, se observó un promedio de 21,1 mcg/dl de iodo con un desvío standar de 6,7 mcg/dl (es decir, iodurias altamente satisfactorias). Se ha decidido profundizar la investigación, determinando anticuerpos TPO y medición TSH, para destacar tiroiditis crónica e hipotiroidismo subclínico
Assuntos
Humanos , Criança , Adolescente , Bócio Endêmico/epidemiologia , Serviços de Saúde Escolar , Argentina/epidemiologia , Estudos Transversais , PrevalênciaRESUMO
El objetivo de este trabajo fue determinar la prevalencia de bocio en escolares de la ciudad de Mar del Plata. Se seleccionó una muestra entre alumnos de 6 a 14 años de edad de escuelas urbanas y periurbanas de la ciudad de Mar del Plata; la muestra se realizó por conglomerados y posteriormente por métodos aleatorios. Se encuestaron 889 alumnos, 54,1 por ciento de sexo masculino y 45,9 por ciento del femenino, y se recolectó orina en un 8,7 por ciento de los varones. Se detectó un 17,2 por ciento del nivel Ia, 1,7 por ciento Ib y 0,1 por ciento II Total = 19 por ciento (según clasificación OPS). No se observaron diferencias significativas respecto al sexo y edad, ni a la provisión de agua corriente y/o de pozo ni a residencia urbana o rural. Si se observó diferencia significativa entre escuelas Estatales y Privadas : 21,2 por ciento y 11,6 por ciento respectivamente. Dado las diferencias observadas entre los distintos equipos de trabajo (todos los profesionales intervinientes con experiencia en palpación de tiroides), se resolvió efectuar ecografía a un 20 por ciento de los positivos más un 10 por ciento de normales : los resultados de las ecografías avalan ampliamente los hallazgos palpatorios. De las 53 muestras de orina procesadas, se observó un promedio de 21,1 mcg/dl de iodo con un desvío standar de 6,7 mcg/dl (es decir, iodurias altamente satisfactorias). Se ha decidido profundizar la investigación, determinando anticuerpos TPO y medición TSH, para destacar tiroiditis crónica e hipotiroidismo subclínico
Assuntos
Humanos , Criança , Adolescente , Bócio Endêmico/epidemiologia , Estudos Transversais , Argentina/epidemiologia , PrevalênciaRESUMO
PURPOSE: The object of this study was to present a series of myxoma in children and to evaluate possible differences between young and adults patients. MATERIALS AND METHODS: All tumors of patients under 16 years of age (10 cases), were separated from the 80 myxomas found in the Oral Pathology Laboratory, Faculty of Odontology, Buenos Aires University, and were analyzed in terms of clinical data, radiographic image, histopathology, treatment, and evolution. RESULTS: Myxoma in childhood represented 12.5% of the 80 cases in our series. The mean age was 11.6 years. Six patients were boys and four were girls. Both jaws were affected equally, predominantly in the premolar-molar region. Eighty percent of the tumors were larger than 2 cm. Only one case was clinically diagnosed as myxoma. Radiologically the most frequent image was unilocular with cortical expansion and tooth displacement. Histologically seven cases were diagnosed as myxoma and three as fibromyxoma. Treatment involved surgical resection in most cases. Two patients showed recurrence within the first year after surgery. CONCLUSIONS: The frequency of myxoma in childhood may be higher than that of other aggressive odontogenic tumors, although some literature refers to this tumor as very uncommon in children. Clinically this tumor may not always be taken into account in the differential diagnosis of intraosseous radiolucencies in young patients. The histologic appearance is similar in young and adult patients, but myxoma in children may be larger. It was not possible to correlate the histologic type of myxoma and the age of the patients.
Assuntos
Neoplasias Maxilomandibulares/patologia , Tumores Odontogênicos/patologia , Adolescente , Criança , Pré-Escolar , Feminino , Fibroma/diagnóstico por imagem , Fibroma/patologia , Fibroma/cirurgia , Humanos , Neoplasias Maxilomandibulares/diagnóstico por imagem , Neoplasias Maxilomandibulares/cirurgia , Masculino , Tumores Odontogênicos/diagnóstico por imagem , Tumores Odontogênicos/cirurgia , RadiografiaRESUMO
A bibliometric study about the subject content of the articles published in the Mexican scientific journal Archives of Medical Research is reported. The journal, published by the Mexican Institute of Social Security (IMSS), is comprised of 100 regular issues and 12 special supplements giving a total amount of 1,424 reports on medical research performed in Mexico during the last 25 years. According to the type of studies published during this period, we found that there is a similar percent of biomedical and clinical reports in the journal (47 and 42%, respectively) and a low proportion of epidemiological and medical educational reports (8 and 3%, respectively). Six thematic areas of research have been permanently published in this journal: investigations on infectious and neurological diseases being the areas mainly represented (34% of the total, corresponding to 17% in each area), followed by studies in reproductive biology (10%) and endocrine (7%), oncological (5%) and cardiovascular (3%) diseases. The tendency of the subjects covered by the journal during this period shows an increment in reports on infectious and parasitic disorders together with an increase in publications related to medicinal plant pharmacology; reproductive biology and endocrine studies show also an increasing tendency. On the other hand, a moderate decrease in studies related to neurological, oncological and cardiovascular diseases is observed. The origin of contributions during the last five years has balanced the proportion of papers published from IMSS scientists, other Mexican biomedical researchers and foreign contributions, thus reflecting favorably the recent changes in the journal's policies. This journal represents a clear example of a scientific publication edited in a developing country, originating as a national publication that evolved progressively into an international biomedical journal.
Assuntos
Bibliometria , Publicações Periódicas como Assunto/história , Animais , História do Século XX , MéxicoRESUMO
Es un estudio tangencial prospectivo realizado en mayo del 1991, y aplicando un cuestionario y características de la masturbación en una población masculina de un liceo de la ciudad capital, Santo Domingo, República Dominicana. El 96.3//de todos la practican; siendo el rango de edad de mayor práctica entre 14 a 19 años (85.8//). El 58//respondieron sentir culpa o vergüenza, 48.3//la practica raras veces o muy ocasionalmente y 62.6//para liberar estress psicológico
Assuntos
Humanos , Masculino , Criança , Adolescente , Adulto , Masturbação/epidemiologiaRESUMO
Literature reports appeared in the last years suggested that some type of dentigerous cyst (DC) in children would initiate by teh action of other factors than developmental and at different stages of dental sac growth. Periodontitis and pulp therapy with formocresol (FC) have been suggested as aeteological factors, both promoting DC in children by irritation of the underlaying dental sacs of premolar. The purpose of this study is to analyse the pathological changes in DC of patients aged 0 to 15 years, and to compare the findings according to the anatomical site of DC and the existence of previous FC therapy. Morphological changes observed in the epithelium and the connective wall did not show clear differences between both groups of DC. The histometric measurements of epithelial changes did not show significant statistical differences of various parameters in the DC walls. These facts would not support the hypotesis of DC initiation from FC effects.