RESUMO
An outbreak of histoplasmosis was spotted in Pedro Leopoldo, a city in Minas Gerais State, Brazil, in 1997, where four individuals had been in contact with a bat-inhabited cave. Acute pulmonary histoplasmosis diagnosis was made by the use of clinical, serologic, radiographic and epidemiological criteria. An antifungal treatment with ketoconazole (400mg daily for 30 days) was administered resulting in symptons' remission in a few days.
Assuntos
Surtos de Doenças , Histoplasmose/epidemiologia , Adolescente , Adulto , Brasil/epidemiologia , Humanos , MasculinoRESUMO
There still exist controversies about the effect of parenteral nutrition on cancer growth. For elucidation of this question the development of Walker 256 carcinosarcoma in rats submitted to parenteral nutrition (PN) was studied. Thirty-five Wistar rats were randomly distributed in three groups: OT group (11), tumor-bearing animals always under oral feeding for 14 days; PC group (14), tumor free animals under PN for 7 days; PT group (10), tumor-bearing rats under PT for 7 days. PT solution contained 15% glucose, 3% aminoacids and essential micronutrients. Body and tumor weight (in OT and PT groups) were evaluated daily. Carcass weight was obtained by the difference between the body and tumor weight. The rats of the PC group had an initial body weight loss that became stabilized afterwards at a lower plateau level. The rats of the PT group also presented an initial body weight loss recovered progressively afterwards. This difference is probably due to tumor mass expansion in PT animals, since PT rats carcass weight remained similar to that of body weight in PC group. The tumor growth has shown no difference between the oral and parenteral feeding groups, particularly when tumor weight/carcass weight ratio was considered. It is concluded that parenteral nutrition does not favor tumor growth in detriment to carcass weight development.
Assuntos
Carcinoma 256 de Walker/patologia , Reação Enxerto-Hospedeiro , Transplante de Neoplasias , Nutrição Parenteral , Animais , Peso Corporal , Estudos de Avaliação como Assunto , Masculino , Distribuição Aleatória , Ratos , Ratos EndogâmicosRESUMO
Os derrames pericárdicos, principalmente septados, podem apresentar sérias dificuldades para sua detecçäo e quantificaçäo pela ecocardiografia convencional. A ecocardiografia bidimensional, em auxílio a modalidade M, permite a detecçäo mais correta dos derrames generalizados, pela regiäo apical e subxifóide. Foram estudados 22 pacientes portadores de derrame pericárdico, dos quais quatro eram septados e oito eram pós-operatórios. Estabeleceram-se as diferenças ecocardiográficas entre os diversos tipos e, em 10 casos, relacionou-se com o aspecto radiológico e com o volume de líquido extraído pela punçäo pericárdica ou pela pericariotomia, mostrando uma razoável correlaçäo (r = 0,76). Conclui-se que a ecocarddiografia bidimensional permite a detecçäo de derrames pericárdicos, especialmente os septados situados fora do alcance do sistema convencional, assim como a sua quantificaçäo, com boa confiabilidade