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1.
Artigo em Inglês | MEDLINE | ID: mdl-38596605

RESUMO

Objective: Chagas disease poses a public health problem in Latin America, and the electrocardiogram is a crucial tool in the diagnosis and monitoring of this pathology. In this context, the aim of this study was to quantify the change in the ability to detect electrocardiographic patterns among healthcare professionals after completing a virtual course. Materials and Methods: An asynchronous virtual course with seven pre-recorded classes was conducted. Participants answered the same questionnaire at the beginning and end of the training. Based on these responses, pre and post-test results for each participant were compared. Results: The study included 1656 participants from 21 countries; 87.9% were physicians, 5.2% nurses, 4.1% technicians, and 2.8% medical students. Initially, 3.1% answered at least 50% of the pre-test questions correctly, a proportion that increased to 50.4% after the course (p=0.001). Regardless of their baseline characteristics, 82.1% of course attendees improved their answers after completing the course. Conclusions: The implementation of an asynchronous online course on electrocardiography in Chagas disease enhanced the skills of both medical and non-medical personnel to recognize this condition.

2.
Rev. argent. cardiol ; 91(2): 117-124, jun. 2023. graf
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1529589

RESUMO

RESUMEN Antecedentes : El diagnóstico diferencial entre la taquicardia reentrante ortodrómica (TRO) y la taquicardia por reentrada nodal atípica (TRNa) puede ser dificultoso. Nuestra hipótesis es que las TRNa tienen más variabilidad en el tiempo de con ducción retrógrada al comienzo de la taquicardia que las TRO. Nuestros objetivos fueron evaluar la variabilidad en el tiempo de conducción retrógrada al inicio de la taquicardia en TRNa y TRO, y proponer una nueva herramienta diagnóstica para diferenciar estas dos arritmias. Métodos : Se midió el intervalo ventrículo-auricular (VA) de los primeros latidos tras la inducción de la taquicardia, hasta su estabilización. La diferencia entre el intervalo VA máximo y el mínimo se definió como delta VA (ΔVA). También contamos el número de latidos necesarios para que se estabilice el intervalo VA. Se excluyeron las taquicardias auriculares. Resultados : Se incluyeron 101 pacientes. Se diagnosticó TRO en 64 pacientes y TRNa en 37. El ΔVA fue 0 (rango intercuartílico, RIC, 0-5) milisegundos (ms) en la TRO frente a 40 (21-55) ms en la TRNa (p < 0,001). El intervalo VA se estabilizó significativamente antes en la TRO (1,5 [1-3] latidos) que en la TRNa (5 [4-7] latidos; p < 0,001). Un ΔVA < 10 ms diagnosticó TRO con 100% de sensibilidad, especificidad y valores predictivos positivo y negativo. La estabilización del intervalo VA en menos de 3 latidos predijo TRO con buena precisión diagnóstica. Los resultados fueron similares considerando sólo vías accesorias septales. Las TRN típicas tuvieron una variación intermedia. Conclusión : Un ΔVA < 10 ms es un criterio simple, que distingue con precisión la TRO de la TRNa, independientemente de la localización de la vía accesoria.


ABSTRACT Background : Differential diagnosis between orthodromic reentrant tachycardia (ORT) and atypical nodal reentrant tachy cardia (ANRT) can be challenging. Our hypothesis was that ANRT presents more variability in retrograde conduction time at tachycardia onset than ORT. Objectives : The objectives of this study were to assess retrograde conduction time variability at the start of tachycardia in ANRT and ORT, and postulate a new diagnostic tool to differentiate these two types of arrhythmias. Methods : The ventriculoatrial (VA) interval of the first beats after tachycardia induction was measured until stabilization. The difference between the maximum and minimum VA interval was defined as delta VA (ΔVA), and the number of beats needed for VA interval stabilization was also assessed. Atrial tachycardias were excluded. Results : In a total of 101 patients included in the study, ORT was diagnosed in 64 patients and ANRT in 37. ΔVA interval was 0 (interquartile range [IQR] 0-5) milliseconds (ms) in ORT vs. 40 (21-55) ms in ANRT (p <0.001). The VA interval significantly stabilized earlier in ORT (1.5 [1-3] beats) than in ANRT (5 [4-7] beats) (p<0.001). A ΔVA <10 ms diagnosed ORT with 100% sensitivity, specificity, and positive and negative predictive values. Ventriculoatrial interval stabilization in less than 3 beats predicted ORT with good diagnostic accuracy. The results were similar considering only accessory septal pathways. Typical NRTs presented an intermediate variation. Conclusion : Presence of DVA <10 ms is a simple criterion that accurately differentiates ORT from ANRT, independently of the accessory pathway localization.

3.
J Interv Card Electrophysiol ; 66(3): 637-645, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-36152135

RESUMO

BACKGROUND: The differential diagnosis between orthodromic atrioventricular reentry tachycardia (AVRT) and atypical AV nodal reentrant tachycardia (aAVNRT) is sometimes challenging. We hypothesize that aAVNRTs have more variability in the retrograde conduction time at tachycardia onset than AVRTs. METHODS: We aimed to assess the variability in retrograde conduction time at tachycardia onset in AVRT and aAVNRT and to propose a new diagnostic tool to differentiate these two arrhythmia mechanisms. We measured the VA interval of the first beats after tachycardia induction until it stabilized. The difference between the maximum and minimum VA intervals (∆VA) and the number of beats needed for the VA interval to stabilize was analyzed. Atrial tachycardias were excluded. RESULTS: A total of 107 patients with aAVNRT (n = 37) or AVRT (n = 64) were included. Six additional patients with decremental accessory pathway-mediated tachycardia (DAPT) were analyzed separately. All aAVNRTs had VA interval variability. The median ∆VA was 0 (0 - 5) ms in AVRTs vs 40 (21 - 55) ms in aAVNRTs (p < 0.001). The VA interval stabilized significantly earlier in AVRTs (median 1.5 [1 - 3] beats) than in aAVNRTs (5 [4 - 7] beats; p < 0.001). A ∆VA < 10 ms accurately differentiated AVRT from aAVNRT with 100% of sensitivity, specificity, and positive and negative predictive values. The stabilization of the VA interval at < 3 beats of the tachycardia onset identified AVRT with sensitivity, specificity, and positive and negative predictive values of 64.1%, 94.6%, 95.3%, and 60.3%, respectively. A ∆VA < 20 ms yielded good diagnostic accuracy for DAPT. CONCLUSIONS: A ∆VA < 10 ms is a simple and useful criterion that accurately distinguished AVRT from atypical AVNRT. Central panel: Scatter plot showing individual values of ∆VA in atypical AVNRT and AVRT. Left panel: induction of atypical AVNRT. The VA interval stabilizes at the 5th beat and the ∆VA is 62 ms (maximum VA interval: 172 ms - minimum VA interval: 110 ms). Right panel: induction of AVRT. The tachycardia has a fixed VA interval from the first beat. ∆VA is 0 ms.


Assuntos
Feixe Acessório Atrioventricular , Taquicardia por Reentrada no Nó Atrioventricular , Taquicardia Reciprocante , Taquicardia Supraventricular , Humanos , Taquicardia por Reentrada no Nó Atrioventricular/diagnóstico , Sistema de Condução Cardíaco , Taquicardia Reciprocante/diagnóstico , Fascículo Atrioventricular , Diagnóstico Diferencial , Eletrocardiografia
8.
J Interv Card Electrophysiol ; 62(3): 461-467, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-33876382

RESUMO

Patients with heart disease, or at high risk of developing a cardiac condition, usually undergo risk assessment by primary care physicians, internal medicine doctors, or cardiologists. There are several methods that can be used for this risk assessment, and their applicability differs with respect to availability, complexity, and usefulness in different geographic populations. This document focuses on some of the many relevant clinical topics recently presented in the "Expert Consensus on Risk Assessment in Cardiac Arrhythmias: Use the Right Tool for the Right Outcome," which include statements based on the best available evidence. In this review, we want to highlight and make some pertinent comments on some of the most relevant points of this Consensus.


Assuntos
Cardiopatias , Taquicardia Ventricular , Arritmias Cardíacas/diagnóstico , Consenso , Humanos , Medição de Risco
10.
J Interv Card Electrophysiol ; 62(3): 557-564, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-33420714

RESUMO

BACKGROUND: There are few reports on the benefits of catheter ablation (CA) in patients with electrical storm (ES). None of these publications included patients with Chagas disease (ChD). Our aims are to analyze (1) all the cases of ES treated with CA and (2) the subgroup of patients with ChD. METHODS: Prospective analysis of consecutive patients with ES due to monomorphic ventricular tachycardia (VT) treated with CA. RESULTS: We included 38 patients: 28 males; median age of 63.5 (IQR 55-71) years old; ejection fraction (LVEF) 0.30 (0.25-0.40). Sixteen patients (42.1%) had ChD. The patients experienced 21 (15-37) VT episodes and received 7 (3-13) ICD shocks before CA. Forty-six procedures were performed (7 required epicardial access). All patients experienced ES suppression after CA. After 35 (10-64) months of follow-up (1.21 procedures per patient), 23 patients (60.5%) remain free from any VT; 35 patients (92.1%) were free from ES, and 11 patients (28.9%) died from non-arrhythmic causes. One patient underwent heart transplantation. Patients with ChD were younger (60 vs. 67 years old; p = 0.033), significantly more women (50% vs. 9.1%; p = 0.005), and had higher LVEF (0.40 vs. 0.28; p < 0.001) than the other patients. Long-term outcome of ChD patients was similar to that of the overall population. Only age and LVEF independently predicted mortality. CONCLUSION: CA was associated with acute ventricular arrhythmia suppression in all patients with ES. Freedom rates from ES and VT were 92.1% and 60.5% respectively. Despite having a lower-risk clinical profile, patients with ChD had a comparable outcome to that of the other patients.


Assuntos
Ablação por Cateter , Doença de Chagas , Taquicardia Ventricular , Idoso , Arritmias Cardíacas , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Volume Sistólico , Taquicardia Ventricular/diagnóstico por imagem , Taquicardia Ventricular/cirurgia , Resultado do Tratamento
11.
Rev. argent. cardiol ; 88(5): 429-433, set. 2020. tab, graf
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1251016

RESUMO

RESUMEN Introducción: La prevención de la muerte súbita y el tratamiento de la insuficiencia cardíaca son temas de gran importancia. Para prevenir la muerte súbita y mejorar el pronóstico de la insuficiencia cardíaca se utilizan los cardiodesfibriladores y cardioresincronizadores. Objetivos: Evaluar la cantidad y tipo de dispositivos implantados en nuestro país, así como las características de los pacientes, las complicaciones agudas y las que se presentan en el seguimiento. Material y métodos: Se realizó un estudio observacional, prospectivo, multicéntrico en centros de salud con la capacidad de implantar cardiodesfibriladores y cardioresincronizadores. Se incluyeron pacientes a los que se les realizó implante de estos dispositivos desde enero del 2016 hasta enero de 2017, con un seguimiento de 12 meses. Resultados: Se incluyeron 249 pacientes (edad promedio de 64,8 ± 13,7 años, 73,9% de sexo masculino, 72,1% con Fey < 35%). La etiología subyacente de la miocardiopatía era isquémica en el 39,8%, dilatada 26,7% y chagásica en el 11,2% de los casos. El 58% de los implantes realizados fueron cardiodesfibriladores y el 39%, cardiodesfibriladores asociados con cardioresincronizadores. El 84% de los procedimientos fueron primoimplantes. La indicación más frecuente del implante fue por prevención primaria de muerte súbita (67,9%). La tasa de complicaciones menores fue del 4,4% y no se reportaron complicaciones mayores. Conclusiones: El siguiente registro evidenció una gran proporción de implantes en pacientes con cardiopatía isquémica, la indicación principal fue por prevención primaria de muerte súbita y la tasa de complicaciones fue similar a la reportada internacionalmente.


ABSTRACT Background: Prevention of sudden death and treatment of heart failure are very important topics. Implantable cardioverter-defibrillator and cardiac resynchronization devices are used to prevent sudden death and improve heart failure symptoms and prognosis. Objectives: The aim of this study was to evaluate the number, type of implanted devices, clinical characteristics of the patients and acute and follow-up complications. Methods: An observational, prospective, multicenter study was carried out in healthcare centers with the capacity to implant cardioverter-defibrillator and cardiac resynchronization devices. The study included all patients who underwent implantation of these devices from January 2016 to January 2017, with a 12-month follow-up. Results: A total of 249 patients (73.9% men) with mean age of 64.8±13.7 years, and 72.1% with ejection fraction <35%, were included in the study. The underlying cardiomyopathy etiology was ischemic in 39.8% of cases, dilated in 26.7% and chagasic in 11.2%. Fifty-eight percent of implants were implantable cardioverter-defibrillators and 39% were cardioverter-defibrillators associated with cardiac resynchronization devices. In 84% of cases, procedures were first implants. The most frequent indica-tion of implantation was for primary prevention of sudden death (67.9%). Minor complication rate was 4.4% and no major complications were reported. Conclusions: The present registry evidenced a large proportion of cardioverter-defibrillator and cardiac resynchronization implants in patients with ischemic heart disease. The main indication was for primary prevention of sudden death and the complication rate was similar to that reported internationally.

15.
Rev. argent. cardiol ; 82(4): 285-291, ago. 2014. ilus, graf, tab
Artigo em Espanhol | LILACS | ID: lil-734512

RESUMO

Introducción La ablación por radiofrecuencia de la fibrilación auricular es más eficaz que las drogas antiarrítmicas en el control de los síntomas, particularmente cuando la arritmia es paroxística. Consiste en un procedimiento laborioso y complejo no exento de complicaciones. Objetivo Evaluar los resultados de la ablación por radiofrecuencia en una población seleccionada consecutiva con fibrilación auricular recurrente y refractaria a drogas antiarrítmicas. Material y métodos Se evaluaron 111 pacientes, 90 hombres, con fibrilación auricular paroxística (n = 75) o persistente (n = 36), refractaria a 2 (1,5-3) drogas antiarrítmicas que fueron seleccionados para la ablación por radiofrecuencia. Todos los procedimientos se realizaron siguiendo una metodología uniforme. La edad fue de 56 ± 11 años, con un diámetro de la aurícula izquierda de 41,5 (39-45) mm y fracción de eyección del ventrículo izquierdo del 60% (56,5-66,5%). Se realizaron 126 procedimientos de ablación por radiofrecuencia, incluyendo 15 segundos procedimientos. Se aislaron 476/489 (97,3%) venas pulmonares. Veinticinco pacientes (22,5%) presentaron actividad ectópica espontánea de las venas pulmonares. Se presentaron complicaciones no mortales en 7/126 procedimientos (5,5%), que se resolvieron satisfactoriamente. Tres pacientes presentaron complicaciones vasculares y se observó una complicación anestésica, un taponamiento cardíaco subagudo, una pericarditis sin derrame y una estenosis de vena pulmonar. Luego de un seguimiento de 22 (13-35) meses, 83 pacientes (74,8%) se mantuvieron en ritmo sinusal sin drogas antiarrítmicas. Los 28 pacientes restantes (25,2%) presentaron recurrencias. Cuatro de ellos respondieron satisfactoriamente a estas drogas (previamente ineficaces), ocho tuvieron fibrilación auricular a pesar de recibir drogas antiarrítmicas y 1 paciente se encuentra en plan de reablación. A los 15 pacientes restantes se les realizó un segundo procedimiento de ablación. Diez de ellos se mantienen sin recurrencias luego de 12 (9-31) meses. Conclusión En esta serie consecutiva de pacientes con fibrilación auricular refractaria a drogas antiarrítmicas, la ablación por radiofrecuencia mostró una tasa de éxito adecuada y un nivel bajo de complicaciones.


Introduction Radiofrequency catheter ablation of atrial fibrillation is more effective than antiarrhythmic drugs for symptoms control, particularly in paroxysmal atrial fibrillation. The procedure is laborious and complex and not exempt from complications. Objective The aim of this study was to evaluate the outcomes of radiofrequency catheter ablation in a consecutive and selected population with recurrent atrial fibrillation refractory to antiarrhythmic drugs. Methods One-hundred and eleven patients (90 men) with paroxysmal (n = 75) or persistent (n = 36) atrial fibrillation, refractory to 2 (1.5-3) antiarrhythmic drugs were selected for radiofrequency catheter ablation. All the procedures were performed following a uniform methodology. Mean age was 56 ± 11 years, left atrial diameter was 41.5 (39-45) mm and left ventricular ejection fraction was 60% (56.5-66.5%). A total of 126 radiofrequency catheter ablation procedures were performed, including 15 second procedures, and 476/489 (97.3%) pulmonary veins were isolated. Twenty-five patients (22.5%) presented spontaneous ectopic activity in the pulmonary veins. Nonfatal complications occurred in 7/126 procedures (5.5%) and were satisfactorily resolved. Three patients presented vascular complications; other complications included one related to anesthesia, one subacute cardiac tamponade, one pericarditis without effusion and one pulmonary vein stenosis. After 22-month follow-up (13-35 months), 83 patients (74.8%) remained in sinus rhythm without antiarrhythmic drugs. The remaining 28 patients (25.2%) presented recurrences. Four of these patients had a favorable response to these previously inefficient drugs, 8 had atrial fibrillation in spite of receiving antiarrhythmic drugs and 1 patient will undergo a new ablation. The remaining 15 patients underwent a second ablation procedure; 10 of them are free of recurrences after 12 (9-31) months. Conclusion In this consecutive series of patients with atrial fibrillation refractory to drugs, radiofrequency catheter ablation showed an adequate rate of success and low level of complications.

16.
Rev. argent. cardiol ; 82(4): 285-291, ago. 2014. ilus, graf, tab
Artigo em Espanhol | BINACIS | ID: bin-131330

RESUMO

Introducción La ablación por radiofrecuencia de la fibrilación auricular es más eficaz que las drogas antiarrítmicas en el control de los síntomas, particularmente cuando la arritmia es paroxística. Consiste en un procedimiento laborioso y complejo no exento de complicaciones. Objetivo Evaluar los resultados de la ablación por radiofrecuencia en una población seleccionada consecutiva con fibrilación auricular recurrente y refractaria a drogas antiarrítmicas. Material y métodos Se evaluaron 111 pacientes, 90 hombres, con fibrilación auricular paroxística (n = 75) o persistente (n = 36), refractaria a 2 (1,5-3) drogas antiarrítmicas que fueron seleccionados para la ablación por radiofrecuencia. Todos los procedimientos se realizaron siguiendo una metodología uniforme. La edad fue de 56 ± 11 años, con un diámetro de la aurícula izquierda de 41,5 (39-45) mm y fracción de eyección del ventrículo izquierdo del 60% (56,5-66,5%). Se realizaron 126 procedimientos de ablación por radiofrecuencia, incluyendo 15 segundos procedimientos. Se aislaron 476/489 (97,3%) venas pulmonares. Veinticinco pacientes (22,5%) presentaron actividad ectópica espontánea de las venas pulmonares. Se presentaron complicaciones no mortales en 7/126 procedimientos (5,5%), que se resolvieron satisfactoriamente. Tres pacientes presentaron complicaciones vasculares y se observó una complicación anestésica, un taponamiento cardíaco subagudo, una pericarditis sin derrame y una estenosis de vena pulmonar. Luego de un seguimiento de 22 (13-35) meses, 83 pacientes (74,8%) se mantuvieron en ritmo sinusal sin drogas antiarrítmicas. Los 28 pacientes restantes (25,2%) presentaron recurrencias. Cuatro de ellos respondieron satisfactoriamente a estas drogas (previamente ineficaces), ocho tuvieron fibrilación auricular a pesar de recibir drogas antiarrítmicas y 1 paciente se encuentra en plan de reablación. A los 15 pacientes restantes se les realizó un segundo procedimiento de ablación. Diez de ellos se mantienen sin recurrencias luego de 12 (9-31) meses. Conclusión En esta serie consecutiva de pacientes con fibrilación auricular refractaria a drogas antiarrítmicas, la ablación por radiofrecuencia mostró una tasa de éxito adecuada y un nivel bajo de complicaciones.(AU)


Introduction Radiofrequency catheter ablation of atrial fibrillation is more effective than antiarrhythmic drugs for symptoms control, particularly in paroxysmal atrial fibrillation. The procedure is laborious and complex and not exempt from complications. Objective The aim of this study was to evaluate the outcomes of radiofrequency catheter ablation in a consecutive and selected population with recurrent atrial fibrillation refractory to antiarrhythmic drugs. Methods One-hundred and eleven patients (90 men) with paroxysmal (n = 75) or persistent (n = 36) atrial fibrillation, refractory to 2 (1.5-3) antiarrhythmic drugs were selected for radiofrequency catheter ablation. All the procedures were performed following a uniform methodology. Mean age was 56 ± 11 years, left atrial diameter was 41.5 (39-45) mm and left ventricular ejection fraction was 60% (56.5-66.5%). A total of 126 radiofrequency catheter ablation procedures were performed, including 15 second procedures, and 476/489 (97.3%) pulmonary veins were isolated. Twenty-five patients (22.5%) presented spontaneous ectopic activity in the pulmonary veins. Nonfatal complications occurred in 7/126 procedures (5.5%) and were satisfactorily resolved. Three patients presented vascular complications; other complications included one related to anesthesia, one subacute cardiac tamponade, one pericarditis without effusion and one pulmonary vein stenosis. After 22-month follow-up (13-35 months), 83 patients (74.8%) remained in sinus rhythm without antiarrhythmic drugs. The remaining 28 patients (25.2%) presented recurrences. Four of these patients had a favorable response to these previously inefficient drugs, 8 had atrial fibrillation in spite of receiving antiarrhythmic drugs and 1 patient will undergo a new ablation. The remaining 15 patients underwent a second ablation procedure; 10 of them are free of recurrences after 12 (9-31) months. Conclusion In this consecutive series of patients with atrial fibrillation refractory to drugs, radiofrequency catheter ablation showed an adequate rate of success and low level of complications.(AU)

17.
Rev. argent. cardiol ; 81(6): 493-497, dic. 2013. graf, tab
Artigo em Espanhol | LILACS | ID: lil-734459

RESUMO

Introducción El puntaje CHADS2 y el recientemente adoptado por la comunidad médica CHA2DS2-VASc se han elaborado con datos de registros internacionales y son ampliamente usados en la práctica clínica. Sin embargo, no se han evaluado en registros nacionales. Objetivos Evaluar el poder de predicción de los puntajes de riesgo de accidente cerebrovascular CHADS2 y CHA2DS2-VASc en el Registro de Fibrilación Auricular realizado por el Área de Investigación de la Sociedad Argentina de Cardiología y secundariamente comparar ambos sistemas de puntaje. Material y métodos El Registro de Fibrilación Auricular realizado en 2001 fue un estudio multicéntrico y prospectivo de todos los pacientes consecutivos asistidos por fibrilación auricular crónica (permanente y persistente) en 70 centros médicos de la Argentina. Se obtuvieron los datos demográficos, las características socioeconómicas, los antecedentes y las características clínicas. Se realizó un seguimiento a 2 años en el que se evaluó la tasa de accidente cerebrovascular. Para el presente análisis se seleccionaron los pacientes sin tratamiento anticoagulante. En esta población se evaluaron los dos sistemas de puntaje de riesgo, se confeccionó una curva de ROC para cada puntaje (que se informa como estadístico C) y se realizó una comparación entre ambos sistemas de puntaje. Resultados El 49,3% (303 pacientes) de los pacientes seguidos no recibían tratamiento anticoagulante y constituyeron nuestra población en estudio. La tasa de accidente cerebrovascular en la población seleccionada fue del 9,5%. Los dos sistemas de puntaje de riesgo predijeron el accidente cerebrovascular significativamente. La tasa de accidente cerebrovascular fue aumentando a medida que aumentaba el puntaje del CHADS2 y el del CHA2DS2-VASc; este aumento fue similar en ambas escalas de riesgo. El estadístico C para accidente cerebrovascular del CHADS2 fue de 0,67 (0,55-0,78) y el del CHA2DS2-VASc fue de 0,69 (0,59-0,78), sin diferencias significativas entre ambos. Con el análisis de los puntajes divididos en tres perfiles de riesgo -bajo, moderado y alto- se observó que el poder de predicción disminuyó notablemente; el valor del estadístico C del CHADS2 fue de 0,63 (IC 95% 0,57-0,68) y el del CHA2DS2-VASc fue de 0,57 (IC 95% 0,51- 22 0,62),una ligera tendencia a predecir mejor el CHADS2 pero sin significación estadística. Conclusiones En una población con fibrilación auricular de la República Argentina se observó que los dos sistemas de puntaje de predicción de accidente cerebrovascular en pacientes con fibrilación auricular permanente y persistente tienen un poder de predicción similar entre ellos y similar al referido en la bibliografía.


Introduction The CHADS2 score and the CHA2DS2-VASc score recently ad-opted by the medical community have been developed with international registry data and are widely used in clinical practice. However, they have not been evaluated in national registries. Objectives The aims of this study were first to evaluate the predictive power of the CHADS2 and CHA2DS2-VASc stroke risk scores in the Atrial Fibrillation Registry conducted by the Argentine Society of Cardiology Research Area and second to compare both scoring systems. Methods The Atrial Fibrillation Registry of 2001 was a multicenter, prospective study of all consecutive patients with chronic atrial fibrillation (permanent, persistent) treated in 70 medical centers in Argentina. Demographic data, socioeco-nomic characteristics, background and clinical features were obtained. A 2-year follow-up was performed to assess stroke rate. For the present analysis patients without anticoagulant treatment were selected. In this population, the two risk score systems were assessed; a ROC curve was built for each score (reported as c-statistic) and a comparison between both scoring systems was performed. Results The study population consisted of 303 patients (49.3%) not receiving anticoagulant therapy. The stroke rate in the se-lected population was 9.5%. Both scoring systems predicted significant stroke risk. The stroke rate increased as the CHADS2 and the CHA2DS2-VASc scores were higher, and were similar in both risk scales. The CHADS2 and CHA2DS2-VASc scores had c-statistic values of 0.67 (0.55-0.78) and 0.69 (0.59-0.78), respectively, without significant differences between them. The score analyses divided into three risk profiles -low, mod-erate and high- revealed that the predictive power decreased markedly. The c-statistic value of the CHADS2 was 0.63 (95% CI 0.57-0.68) and that of the CHA2DS2-VASc score was 0.57 (95% CI 0.51-0.62), with a slightly better predictive trend for the CHADS2 score but without statistical significance. Conclusions The two scoring systems used to predict stroke in an Argen-tine population of patients with persistent and permanent atrial fibrillation have a similar predictive power in accor-dance with results reported in the literature.

18.
Rev. argent. cardiol ; 81(6): 493-497, dic. 2013. graf, tab
Artigo em Espanhol | BINACIS | ID: bin-129771

RESUMO

Introducción El puntaje CHADS2 y el recientemente adoptado por la comunidad médica CHA2DS2-VASc se han elaborado con datos de registros internacionales y son ampliamente usados en la práctica clínica. Sin embargo, no se han evaluado en registros nacionales. Objetivos Evaluar el poder de predicción de los puntajes de riesgo de accidente cerebrovascular CHADS2 y CHA2DS2-VASc en el Registro de Fibrilación Auricular realizado por el Area de Investigación de la Sociedad Argentina de Cardiología y secundariamente comparar ambos sistemas de puntaje. Material y métodos El Registro de Fibrilación Auricular realizado en 2001 fue un estudio multicéntrico y prospectivo de todos los pacientes consecutivos asistidos por fibrilación auricular crónica (permanente y persistente) en 70 centros médicos de la Argentina. Se obtuvieron los datos demográficos, las características socioeconómicas, los antecedentes y las características clínicas. Se realizó un seguimiento a 2 años en el que se evaluó la tasa de accidente cerebrovascular. Para el presente análisis se seleccionaron los pacientes sin tratamiento anticoagulante. En esta población se evaluaron los dos sistemas de puntaje de riesgo, se confeccionó una curva de ROC para cada puntaje (que se informa como estadístico C) y se realizó una comparación entre ambos sistemas de puntaje. Resultados El 49,3% (303 pacientes) de los pacientes seguidos no recibían tratamiento anticoagulante y constituyeron nuestra población en estudio. La tasa de accidente cerebrovascular en la población seleccionada fue del 9,5%. Los dos sistemas de puntaje de riesgo predijeron el accidente cerebrovascular significativamente. La tasa de accidente cerebrovascular fue aumentando a medida que aumentaba el puntaje del CHADS2 y el del CHA2DS2-VASc; este aumento fue similar en ambas escalas de riesgo. El estadístico C para accidente cerebrovascular del CHADS2 fue de 0,67 (0,55-0,78) y el del CHA2DS2-VASc fue de 0,69 (0,59-0,78), sin diferencias significativas entre ambos. Con el análisis de los puntajes divididos en tres perfiles de riesgo -bajo, moderado y alto- se observó que el poder de predicción disminuyó notablemente; el valor del estadístico C del CHADS2 fue de 0,63 (IC 95% 0,57-0,68) y el del CHA2DS2-VASc fue de 0,57 (IC 95% 0,51- 22 0,62),una ligera tendencia a predecir mejor el CHADS2 pero sin significación estadística. Conclusiones En una población con fibrilación auricular de la República Argentina se observó que los dos sistemas de puntaje de predicción de accidente cerebrovascular en pacientes con fibrilación auricular permanente y persistente tienen un poder de predicción similar entre ellos y similar al referido en la bibliografía.(AU)


Introduction The CHADS2 score and the CHA2DS2-VASc score recently ad-opted by the medical community have been developed with international registry data and are widely used in clinical practice. However, they have not been evaluated in national registries. Objectives The aims of this study were first to evaluate the predictive power of the CHADS2 and CHA2DS2-VASc stroke risk scores in the Atrial Fibrillation Registry conducted by the Argentine Society of Cardiology Research Area and second to compare both scoring systems. Methods The Atrial Fibrillation Registry of 2001 was a multicenter, prospective study of all consecutive patients with chronic atrial fibrillation (permanent, persistent) treated in 70 medical centers in Argentina. Demographic data, socioeco-nomic characteristics, background and clinical features were obtained. A 2-year follow-up was performed to assess stroke rate. For the present analysis patients without anticoagulant treatment were selected. In this population, the two risk score systems were assessed; a ROC curve was built for each score (reported as c-statistic) and a comparison between both scoring systems was performed. Results The study population consisted of 303 patients (49.3%) not receiving anticoagulant therapy. The stroke rate in the se-lected population was 9.5%. Both scoring systems predicted significant stroke risk. The stroke rate increased as the CHADS2 and the CHA2DS2-VASc scores were higher, and were similar in both risk scales. The CHADS2 and CHA2DS2-VASc scores had c-statistic values of 0.67 (0.55-0.78) and 0.69 (0.59-0.78), respectively, without significant differences between them. The score analyses divided into three risk profiles -low, mod-erate and high- revealed that the predictive power decreased markedly. The c-statistic value of the CHADS2 was 0.63 (95% CI 0.57-0.68) and that of the CHA2DS2-VASc score was 0.57 (95% CI 0.51-0.62), with a slightly better predictive trend for the CHADS2 score but without statistical significance. Conclusions The two scoring systems used to predict stroke in an Argen-tine population of patients with persistent and permanent atrial fibrillation have a similar predictive power in accor-dance with results reported in the literature.(AU)

20.
Indian Pacing Electrophysiol J ; 12(3): 133-5, 2012 May.
Artigo em Inglês | MEDLINE | ID: mdl-22665963

RESUMO

A 36 year-old man with Wolff Parkinson White syndrome due to a left-sided accessory pathway (AP) was referred for catheter ablation. Whether abolition of antegrade and retrograde AP conduction during ablation therapy occurs simultaneously, is unclear. At the ablation procedure, radiofrequency delivery resulted in loss of preexcitation followed by a short run of orthodromic tachycardia with eccentric atrial activation, demonstrating persistence of retrograde conduction over the AP after abolition of its antegrade conduction. During continued radiofrequency delivery at the same position, the fifth non-preexcitated beat failed to conduct retrogradely and the tachycardia ended. In this case, antegrade AP conduction was abolished earlier than retrograde conduction.

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